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在“Elsevier电子期刊”中，命中：32条，耗时：小于0.01 秒

1.Combined effect of G3139 and TSPO ligands on Ca²⁺-induced permeability transition in rat brain mitochondria

关键词：VDAC ; TSPO ; Mitochondria ; Permeability transition pore ; PK11195 ; G3139

刊名：Archives of Biochemistry and Biophysics

出版年：2015

2.Delivery of G3139 using releasable PEG-linkers: Impact on pharmacokinetic profile and anti-tumor efficacy

作者：Hong Zhao ; Ping Peng ; Clifford Longley ; Yue Zhang ; Virna Borowski ; Mary Mehlig ; Prasanna Reddy ; Jing Xia ; Gerrit Borchard ; Jack Lipman ; et al.

关键词：PEG (polyethylene glycol) ; G3139 ; Pharmacokinetics ; 518A2 melanoma ; Immunostimulation

刊名：Journal of Controlled Release

出版年：2007

3.VDAC blockage by phosphorothioate oligonucleotides and its implication in apoptosis

作者：Wenzhi Tan ; ^{wenzhi.tan@jefferson.edu}

关键词：ANT ; adenine nucleotide translocator ; ER ; endoplasmic reticulum ; MIM ; mitochondrial inner membrane ; MOM ; mitochondrial outer membrane ; PO ; phosphodiester ; PS ; phosphorothioate ; PTP ; permeability transition pore ; ROS ; reactive oxygen species

刊名：Biochimica et Biophysica Acta (BBA)/Biomembranes

出版年：2012

4.Delivery of antisense oligodeoxyribonucleotide lipopolyplex nanoparticles assembled by microfluidic hydrodynamic focusing

作者：Chee Guan Koh ; Xulang Zhang ; Shujun Liu ; Sharon Golan ; Bo Yu ; Xiaojuan Yang ; Jingjiao Guan ; Yan Jin ; Yeshayahu Talmon ; Natarajan Muthusamy ; Kenneth K Chan ; John C. Byrd ; Robert J. Lee ; Guido Marcucci

关键词：Microfluidics ; Liposome ; Antisense ODN ; G3139 ; Lipopolyplex ; Bcl-2 down-regulation ; Nanoparticle

刊名：Journal of Controlled Release

出版年：2010

5.Why G3139 works poorly in cancer trials but might work well against HIV

作者：George E. Parris

关键词：visualization ; peaches ; acoustic velocity ; acoustic attenuation

刊名：Medical Hypotheses

出版年：2007

6.Closure of VDAC causes oxidative stress and accelerates the Ca²⁺-induced mitochondrial permeability transition in rat liver mitochondria

作者：Andrey Tikunov ; C. Bryce Johnson ; Peter Pediaditakis ; Nikolai Markevich ; Jeffrey M. Macdonald ; John J. Lemasters ; Ekhson Holmuhamedov

关键词：Voltage dependent anion channel ; Mitochondria ; Superoxide ; Oxidative stress ; Mitochondrial permeability transition

刊名：Archives of Biochemistry and Biophysics

出版年：2010

7.Efficient delivery of a Bcl-2-specific antisense oligodeoxyribonucleotide (G3139) via transferrin receptor-targeted liposomes

作者：Shih-Jiuan Chiu ; Shujun Liu ; Danilo Perrotti ; Guido Marcucci and Robert J. Lee

关键词：Antisense oligonucleotide ; Transferrin ; Bcl-2 ; Liposomes ; Leukemia

刊名：Journal of Controlled Release

出版年：2006

8.Targeted nanoparticles enhanced flow electroporation of antisense oligonucleotides in leukemia cells

作者：Shengnian Wang ; Xulang Zhang ; Bo Yu ; Robert J. Lee ; L. James Lee

关键词：Electroporation ; Lipoplex ; Microfluidics ; Gene delivery ; Antisense ODN

刊名：Biosensors and Bioelectronics

出版年：2010

9.Characterization and quantification of Bcl-2 antisense G3139 and metabolites in plasma and urine by ion-pair reversed phase HPLC coupled with electrospray ion-trap mass spectrometry

作者：Guowei Dai ; Xiaohui Wei ; Zhongfa Liu ; Shujun Liu ; Guido Marcucci and Kenneth K. Chan

关键词：Pharmacokinetics ; Tandem mass spectrometry ; Metabolism ; Bcl-2 antisense ; N-in-one quantification

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2005

10.New approaches in acute myeloid leukemia

作者：William Blum ; Guido Marcucci

关键词：acute myeloid leukemia ; epigenetics ; targeted therapy ; ribonucleotide reductase ; G3139 (oblimersen sodium ; Genasense) ; core binding factor ; KIT mutation ; RAS mutation

刊名：Best Practice Research Clinical Haematology

出版年：2008

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