搜索页_ Growth factor/Phosphoinositide-3-kinase/Protein kinase B

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在“Elsevier电子期刊”中，命中：16,690条，耗时：0.0969202 秒

在所有数据库中总计命中：109,050条

1.Structural characterization of recombinant human fibroblast growth factor receptor 2b kinase domain upon interaction with omega fatty acids

作者：Masoumeh Moghadasi^a ; ¹ ; Dariush Ilghari^b ; ¹ ; Majid Sirati-Sabet^c ; Abbas Amini^d ; ^e ; ^{a.amini@westernsydney.edu.au} ; ^{a.amini@ack.edu.kw} ; Hamideh Asghari^a ; Nematollah Gheibi^f ; ^{ngheibi@qums.ac.ir}

关键词：hFGFR2b ; human fibroblast growth factor receptor 2b ; UFAs ; unsaturated fatty acids ; CD ; circular dichroism ; FGFRs ; fibroblast growth factor receptors ; RTK ; receptor tyrosine kinase ; Ig ; immunoglobulin ; PLCγ ; phospholipase Cγ ; FRS2 ; fibroblast growth factor substrate 2 ; AS ; apert syndrome ; LADD ; Lacrimo-Auriculo-Dento-Digital Syndrome ; OA ; oleic acid ; LA ; linoleic acid ; ALA ; α-linolenic acid ; EtOH ; ethanol ; IPTG ; isopropyl -d-1-thiogalactopyranoside &minus ; PLCG1 ; phospholipase C ; gamma 1 ; Trp ; t

刊名：Chemistry and Physics of Lipids

出版年：2017

2.Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations

作者：Natasha B. Leighl¹ ; Naiyer A. Rizvi² ; Lopes Gilberto de Lima Jr.³ ; ⁴ ; Wichit Arpornwirat⁵ ; Charles M. Rudin⁶ ; Alberto A. Chiappori⁷ ; Myung-Ju Ahn⁸ ; Laura Q.M. Chow⁹ ; Lyudmila Bazhenova¹⁰ ; Arunee Dechaphunkul¹¹ ; Patrapim Sunpaweravong¹² ; Keith Eaton¹³ ; ¹⁴ ; Jihong Chen¹⁵ ; Sonja Medley¹⁵ ; Srinivasu Poondru¹⁵ ; Margaret Singh¹⁵ ; Joyce Steinberg¹⁵ ; Rosalyn A. Juergens¹⁶ ; ^{juergensr@hhsc.ca} ; Shirish M. Gadgeel¹⁷ ; ¹⁸

关键词：Combination ; Epidermal growth factor receptor inhibitor ; First-line therapy ; Insulin-like growth factor-1 inhibitor ; Tyrosine kinase inhibitor

刊名：Clinical Lung Cancer

出版年：2017

3.A naturally occurring mixture of tocotrienols inhibits the growth of human prostate tumor, associated with epigenetic modifications of cyclin-dependent kinase inhibitors p21 and p27

作者：Ying Huang^a ; ¹ ; Renyi Wu^a ; ¹ ; Zheng-Yuan Su^a ; ^c ; Yue Guo^a ; Xi Zheng^b ; Chung S. Yang^b ; Ah-Ng Kong^a ; ^{KongT@pharmacy.rutgers.edu}

关键词：T3 ; tocotrienol ; T ; tocopherol ; HDAC ; histone deacetylase ; HAT ; histone acetyltransferase ; CDK ; cyclin-dependent kinase

刊名：The Journal of Nutritional Biochemistry

出版年：2017

4.Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer

作者：Paola Francica ; Daniel M. Aebersold ; Michaela Medová ; ; ^{michaela.medova@dkf.unibe.ch}

关键词：ATIR ; anti-tumor immune response ; ATM ; ataxia telangiectasia mutated ; CDK ; cyclin-dependent kinase ; CGH ; comparative genomic hybridization ; CHK1 ; checkpoint kinase 1 ; CHK2 ; checkpoint kinase 2 ; DDAs ; DNA-damaging agents ; DDR ; DNA damage response ; DSBs ; double-strand breaks ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; EPHA3 ; EPH Receptor A3 ; FGFR ; fibroblast growth factor receptor ; FOXM1 ; Forkhead box protein M1 ; GAS6 ; growth arrest-specific protein 6 ; H3K9me3 ; histone 3

刊名：Biochemical Pharmacology

出版年：2017

5.Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance

作者：Nicole Willemsen-Seegers¹ ; Joost C.M. Uitdehaag¹ ; Martine B.W. Prinsen¹ ; Judith R.F. de Vetter¹ ; Jos de Man¹ ; Masaaki Sawa² ; Yusuke Kawase² ; Rogier C. Buijsman¹ ; Guido J.R. Zaman¹ ; ^{guido.zaman@ntrc.nl}

关键词：FDA ; US Food and Drug Administration ; EGFR ; epidermal growth factor receptor ; BTK ; Bruton's tyrosine kinase ; SPR ; surface plasmon resonance ; PI3K ; phosphoinositide 3-kinase ; SD ; standard deviation ; SE ; standard error ; PI3K ; phosphoinositide 3-kinase ; SPR ; surface plasmon resonance

刊名：Journal of Molecular Biology

出版年：2017

6.Fibroblast growth factor 9 (FGF9) regulation of cyclin D1 and cyclin-dependent kinase-4 in ovarian granulosa and theca cells of cattle

作者：M.L. Totty ; B.C. Morrell ; L.J. Spicer ; ^{leon.spicer@okstate.edu}

关键词：Fibroblast growth factor 9 (FGF9) ; Cyclin-dependent kinase 4 (CDK4) ; Cyclin D1 (CCND1) ; Granulosa cells ; Theca cells ; Cattle

刊名：Molecular and Cellular Endocrinology

出版年：2017

7.Up-regulation of insulin-like growth factor 2 by ketamine requires glycogen synthase kinase-3 inhibition

作者：Steven F. Grieco^a ; ^b ; Yuyan Cheng^a ; ^b ; Hagit Eldar-Finkelman^c ; Richard S. Jope^a ; ^b ; Elé ; onore Beurel^a ; ^b ; ^{ebeurel@med.miami.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Ketamine ; Glycogen synthase kinase-3 ; Insulin-like growth factor 2 ; Depression ; Hippocampus ; Learned helplessness

刊名：Progress in Neuropsychopharmacology & Biological Psychiatry

出版年：2017

8.Down-regulation of fibroblast growth factor 2 and its co-receptors heparan sulfate proteoglycans by resveratrol underlies the improvement of cardiac dysfunction in experimental diabetes

作者：Cé ; lia Maria Cá ; ssaro Strunz ; ^{labcelia@incor.usp.br} ; Alessandra Roggerio ^{alessandra.roggerio@incor.usp.br} ; Paula Lá ; zara Cruz ^{paulalcruz@gmail.com} ; Ana Paula Pacanaro ^{ana.pacanaro@incor.usp.br} ; Vera Maria Cury Salemi ^{verasalemi@uol.com.br} ; Luiz Alberto Benvenuti ^{benvenutianpluiz@incor.usp.br} ; Antonio de Pá ; dua Mansur ^{antonio.mansur@incor.usp.br} ; Maria Clá ; udia Irigoyen ^{maria.irigoyen@incor.usp.br}

关键词：A ; Late diastolic mitral inflow ; A&rsquo ; late diastolic peak velocity ; AMPK ; AMP-activated protein kinase ; BMI ; Body mass index ; E ; Early diastolic mitral inflow ; E&rsquo ; early diastolic peak velocity ; FGF ; Fibroblast Growth Factor ; GAPDH ; Glyceraldehyde 3-phosphate dehydrogenase ; HSPGs ; Heparan sulfate proteoglycans ; IVRT ; Isovolumic relaxation time ; LV ; Left ventricular ; N-A ; Naso-anal length ; PPARα ; Peroxisome proliferator-activated receptor alpha ; PPARγ ; Peroxisome proliferator-activated

刊名：The Journal of Nutritional Biochemistry

出版年：2017

9.The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

10.Discovering novel 7-azaindole-based series as potent AXL kinase inhibitors

作者：Clé ; mence Feneyrolles ; Lé ; a Guiet ; Mathilde Singer ; Nathalie Van Hijfte ; Bé ; né ; dicte Daydé ; -Cazals ; Bé ; né ; dicte Fauvel ; Gwé ; naë ; l Chevé ; Abdelaziz Yasri ; ^{ayasri@oribase-pharma.com}

关键词：AXL ; 7-Azaindole ; Receptor tyrosine kinase ; Kinase inhibitor ; Modeling study ; Medicinal chemistry

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

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