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在“Elsevier电子期刊”中，命中：128条，耗时：小于0.01 秒

1.Design, synthesis and evaluation of 4-aminoquinoline-purine hybrids as potential antiplasmodial agents

作者：P. Linga Reddy^a ; Shabana I. Khan^b ; Prija Ponnan^a ; Mohit Tripathi^a ; Diwan S. Rawat^a ; ^{dsrawat@chemistry.du.ac.in}

关键词：Antimalarial hybrids ; Aminoquinoline ; Antiplasmodial activity ; Heme binding activity ; Docking studies

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Chronic alcohol administration affects purine nucleotide catabolism in vivo

关键词：Alcohol dependence ; Purine nucleotide ; Uric acid ; Metabolism

刊名：Life Sciences

出版年：2017

3.Hypouricemic effect of allopurinol are improved by Pallidifloside D based on the uric acid metabolism enzymes PRPS, HGPRT and PRPPAT

作者：Hong-Gang Li^a ; ¹ ; Pi-Yong Hou^a ; ¹ ; Xi Zhang^a ; ¹ ; Yi He^a ; Jun Zhang^a ; Shu-Qing Wang^a ; Samantha Anderson^b ; Yan-Wen Zhang^a ; Xiao-Hui Wu^a ; ^b ; ^{longhui804@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：PRPS ; phosphoribosyl pyrophosphate synthetase ; HGPRT ; hypoxanthine-guanine phosphoribosyl transferase ; PRPPAT ; phosphoribosyl pyrophosphate amino-transferase ; PRPP ; 5-ribose phosphate-1-pyrophosphoric acid ; XOD ; xanthine oxidase ; IMP ; inosine monophosphate ; AMP ; adenine monophosphate ; GMP ; guanine monophosphate ; EtOH ; ethyl alcohol ; BuOH ; n-butyl alcohol ; HR-ESI-MS ; high-resolution mass spectrometer ; NMR ; nuclear magnetic resonance ; UA ; uric acid ; NC ; normal control

刊名：Fitoterapia

出版年：2016

4.Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors

作者：Md Yousuf Ansari^a ; ^b ; Asif Equbal^c ; Manas Ranjan Dikhit^b ; Rani Mansuri^a ; ^b ; Sindhuprava Rana^b ; Vahab Ali^c ; Ganesh Chandra Sahoo^b ; ^{ganeshiitkgp@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; ^{ganeshcs@icmr.org.in" class="auth_mail" title="E-mail the corresponding author} ; Pradeep Das^a ; ^b

关键词：HGPRT ; hypoxanthine-guanine phosphoribosyltransferase ; HPRT ; hypoxanthine phosphoribosyltransferase ; APRT ; adenosine phosphoribosyltransferase ; XPRT ; xanthine phosphoribosyltransferase ; CL ; cutaneous leishmaniasis ; MCL ; muco-cutaneous leishmaniasis ; VL ; visceral leishmaniasis ; PKDL ; post-Kala-azar dermal leishmaniasis ; BLAST ; basic local alignment search tool ; PDB ; protein data bank ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; RMSD ; root mean square deviation ; GMP ; guanosi

刊名：International Journal of Biological Macromolecules

出版年：2016

5.Protective inflammatory response against visceral leishmaniasis with potato tuber extract: A new approach of successful therapy

作者：Dibyendu Paik^a ; Partha Das^a ; Kshudiram Naskar^b ; Pijush Kanti Pramanik^a ; Tapati Chakraborti ; PhD Dr.^a ; ^{tcbiochem@gmail.com" class="auth_mail" title="E-mail the corresponding author} (Professor)

关键词：PTEx ; potato tuber extract ; NO ; nitric oxide ; ROS ; reactive oxygen species ; VL ; visceral leishmaniasis ; CL ; cutaneous leishmaniasis ; MCL ; mucocutaneous leishmaniasis ; LPS ; lipopolysaccharide ; DMSO ; dimethyl sulfoxide ; SAG ; sodium antimony gluconate ; PBS ; phosphate buffer saline ; H2DCFDA ; 2&prime ; 7&prime ; -dichlorodihydrofluorescein diacetate ; DAF-2DA ; 4 ; 5-diaminofluorescein diacetate ; HGPRT ; hypoxanthin &ndash ; eguanine phosphoribosyl transferase ; SAG ; Soduim antimony gluconate

刊名：Biomedicine & Pharmacotherapy

出版年：2016

6.Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis

作者：Nannan Zhang^a ; ¹ ; Xiaojian Gong^a ; ¹ ; Min Lu^a ; Xiaofang Chen^a ; Ximing Qin^a ; Honghua Ge^a ; ^b ; ^{ghh_ahu@foxmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Legionella pneumophila ; Hypoxanthine&ndash ; guanine phosphoribosyltransferase ; Crystal structure ; GMP binding site

刊名：Journal of Structural Biology

出版年：2016

7.Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients

作者：Sally A. Coulthard^a ; ^{sally.coulthard@newcastle.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Phil Berry^b ; Sarah McGarrity^b ; Azhar Ansari^c ; Christopher P.F. Redfern^b

关键词：ALL ; Acute childhood leukemia ; 6-MP or MP ; 6-mercaptopurine ; AZA ; azathioprine ; IBD ; inflammatory bowel disease ; MeMP ; methylmercaptopurine ; MeMP-d3 ; Methymercaptopurine-D3 ; TIMP ; thioinosine monophosphate ; TIDP ; thioinosine diphosphate ; TITP ; thioinosine triphosphate ; TXMP ; thioxanthine monophosphate ; TGMP ; thioguanosine monophosphate ; TGDP ; thioguanosine diphosphate ; TGTP ; thioguanosine triphosphate ; IMPDH ; inosine-monophosphate dehydrogenase ; TPMT ; thiopurine methyl-transferase ; HGPRT ; hypoxa

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

8.Purine metabolism in response to hypoxic conditions associated with breath-hold diving and exercise in erythrocytes and plasma from bottlenose dolphins (Tursiops truncatus)

作者：Iris del Castillo Velasco-Martí ; nez^a ; ^{idelcastillo@pg.cibnor.mx" class="auth_mail" title="E-mail the corresponding author} ; Claudia J. Herná ; ndez-Camacho^b ; ^{cjhernandez78@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Lí ; a C. Mé ; ndez-Rodrí ; guez^a ; ^{lmendez04@cibnor.mx" class="auth_mail" title="E-mail the corresponding author} ; Tania Zenteno-Saví ; n^a ; ^{tzenteno04@cibnor.mx" class="auth_mail" title="E-mail the corresponding author}

关键词：Breath-hold diving ; Bottlenose dolphin ; Erythrocytes ; Exercise ; Hypoxia ; Purine metabolism ; Purine salvage

刊名：Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology

出版年：2016

9.Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase

作者：Sourav Roy ; Lakshmeesha K. Nagappa¹ ; Vasudeva S. Prahladarao¹ ; ² ; Hemalatha Balaram ; ^{hb@jncasr.ac.in" class="auth_mail" title="E-mail the corresponding author}

关键词：PfHGXPRT ; Kinetic mechanism ; IMP pyrophosphorolysis ; Pre-steady-state kinetics ; Single-turnover

刊名：Molecular & Biochemical Parasitology

出版年：2015

10.The pharmacokinetic effect of adalimumab on thiopurine metabolism in Crohn's disease patients

作者：D.R. Wong ; M. Pierik ; M.L. Seinen ; A.A. van Bodegraven ; L.P.L. Gilissen ; P. Bus ; J.A. Bakker ; A.A.M. Masclee ; C. Neef ; L.G.J.B. Engels ; P.M. Hooymans

关键词：AZA ; azathioprine ; CDAI ; Crohn's disease activity index ; 95% CI ; 95% confidence interval ; CRP ; C-reactive protein ; CD ; Crohn's disease ; HGPRT ; hypoxanthine-guanine phosphoribosyl transferase ; HPLC ; high performance liquid chromatography ; IBD ; inflammatory bowel disease ; IMP ; inosine monophosphate ; ITPase ; inosine triphosphate pyrophosphatase ; 6-MMPR ; 6-methylmercaptopurine ribonucleotides ; 6-MP ; mercaptopurine ; MCV ; mean corpuscular volume ; RBC ; red blood cells ; TDM ; therapeutic drug monitoring

刊名：Journal of Crohn's and Colitis

出版年：1 February, 2014

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