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在“Elsevier电子期刊”中，命中：200,404条，耗时：0.1889107 秒

在所有数据库中总计命中：606,821条

1.Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4′fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells

作者：Zuzana Sol&aacute ; rov&aacute ; ^a ; Martin Kello^a ; Lenka Varinsk&aacute ; ^a ; Mariana Budovsk&aacute ; ^b ; Peter Sol&aacute ; r^c ; ^{peter.solar@upjs.sk}

关键词：thiazine[6 ; 5-b]indole ; 2-(4&prime ; fluoro-phenylamino)-4H-1 ; 3-thiazine[6 ; 5-b]indole ; Hsp ; heat shock protein ; 17-DMAG ; 17-dimethylaminoethylamino-17-demethoxygeldanamycin ; 17-AAG ; 17-(allylamino)-17-demethoxygeldanamycin ; A2780 ; human ovarian adenocarcinoma cell line ; A2780cis ; human ovarian adenocarcinoma cell line resistant to cisplatin ; PARP ; poly (ADP-ribose) polymerase ; MMP ; mitochondrial membrane potential ; An ; annexin ; PI ; propidium iodide

刊名：Biomedicine & Pharmacotherapy

出版年：2017

2.Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex

作者：Xiaotian Dong^a ; ¹ ; ^{xiaotiandong@zju.edu.cn} ; Xiaoru Su^b ; ¹ ; ^{sxr1240@163.com} ; Jiong Yu^a ; ^{yujiong@zju.edu.cn} ; Jingqi Liu^a ; ^{jqliu97@zju.edu.cn} ; Xiaowei Shi^c ; ^{sxwschy@163.com} ; Qiaoling Pan^a ; ^{qiaolingpan@zju.edu.cn} ; Jinfeng Yang^a ; ^{jinfengjinfengyang@163.com} ; Jiajia Chen^a ; ^{jiajiatale@163.com} ; Lanjuan Li^a ; ^{ljli@zju.edu.cn} ; Hongcui Cao^a ; ^{hccao@zju.edu.cn} ; ^{zjucaohc@163.com}

关键词：HIF2α ; hypoxia-inducible factor 2α ; VHL ; Von Hippel&ndash ; Lindau ; pVHL ; von Hippel Lindau tumor suppressor protein ; CODD ; C-terminal oxygen-dependent degradation domain ; 3D ; three-dimensional ; ARNT ; aryl hydrocarbon receptor nuclear translocator ; HRE ; hypoxia response element ; EPO ; erythropoietin ; VEGF ; vascular endothelial growth factor ; GLUT1 ; glucose transporter 1 ; EDN1 ; endothelin 1 ; TFDP3 ; transcription factor DP family member 3 ; NMR ; nuclear magnetic resonance ; Blastp ; protein&ndash ; protei

刊名：Journal of Molecular Graphics and Modelling

出版年：2017

3.Knockdown of HIPK2 attenuates the pro-fibrogenic response of hepatic stellate cells induced by TGF-β1

作者：Ping He^a ; Zu-jiang Yu^a ; Chang-yu Sun^a ; ^{changyu467sun@163.com} ; Shu-jie Jiao^b ; He-qing Jiang^a

关键词：Liver fibrosis ; Homeodomain-interacting protein kinase 2 (HIPK2) ; Hepatic stellate cells (HSCs) ; TGF-β1/Smad pathway

刊名：Biomedicine & Pharmacotherapy

出版年：2017

4.Reactive oxygen species-driven HIF1α triggers accelerated glycolysis in endothelial cells exposed to low oxygen tension

作者：Jin-Young Paik^a ; ¹ ; Kyung-Ho Jung^a ; ^b ; ¹ ; Jin-Hee Lee^a ; ^b ; Jin-Won Park^a ; ^b ; Kyung-Han Lee^a ; ^b ; ^{khnm.lee@samsung.com}

关键词：Endothelial cell ; Glycolysis ; 18F&ndash ; FDG ; Hypoxia ; HIF1α ; ROS

刊名：Nuclear Medicine and Biology

出版年：2017

5.mRNA overexpression of the hypoxia inducible factor 1 alpha subunit gene (HIF1A): An independent predictor of poor overall survival in chronic lymphocytic leukemia

作者：Christos K. Kontos^a ; ^b ; ¹ ; Sotirios G. Papageorgiou^a ; ¹ ; Marios A. Diamantopoulos^b ; Andreas Scorilas^b ; Efthimia Bazani^a ; Diamantina Vasilatou^a ; Konstantinos Gkontopoulos^a ; Eirini Glezou^a ; Georgia Stavroulaki^a ; George Dimitriadis^a ; Vasiliki Pappa^a ; ^{vas_pappa@yahoo.com}

关键词：ARNT ; aryl hydrocarbon receptor nuclear translocator ; BCa ; bias-corrected and accelerated ; CLL ; chronic lymphocytic leukemia ; bp ; base pair ; CI ; confidence interval ; HIF ; hypoxia-inducible factor ; HIF1A ; hypoxia inducible factor 1 regulatory α-subunit ; HR ; hazard ratio ; IGHV ; immunoglobulin heavy chain variable region ; LDH ; lactate dehydrogenase ; OS ; overall survival ; PBMC ; peripheral blood mononuclear cell ; PCR ; polymerase chain reaction ; qPCR ; quantitative real-time PCR ; RQU ; relative quantifi

刊名：Leukemia Research

出版年：2017

6.3-Amino-thieno[2,3-b]pyridines as microtubule-destabilising agents: Molecular modelling and biological evaluation in the sea urchin embryo and human cancer cells

作者：Chatchakorn Eurtivong^a ; Victor Semenov^b ; Marina Semenova^c ; ^d ; Leonid Konyushkin^b ; Olga Atamanenko^b ; J&oacute ; hannes Reynisson^a ; ^{j.reynisson@auckland.ac.nz} ; Alex Kiselyov^e

关键词：Microtubule-destabilisation ; Sea urchin embryo assay ; Anticancer ; Thieno[2 ; 3-b]pyridines ; Molecular modelling

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

7.Rhythmic Oxygen Levels Reset Circadian Clocks through HIF1α

作者：Yaarit Adamovich¹ ; ³ ; Benjamin Ladeuix¹ ; ³ ; Marina Golik¹ ; Maarten P. Koeners² ; Gad Asher¹ ; ⁴ ; ^{gad.asher@weizmann.ac.il}

关键词：circadian rhythms ; clock ; oxygen ; HIF1 ; jetlag ; metabolism ; entrainment ; Cry2 ; Rorα

刊名：Cell Metabolism

出版年：2017

8.Synthetic strategy for increasing solubility of potential FLT3 inhibitor thieno[2,3-d]pyrimidine derivatives through structural modifications at the C₂ and C₆ positions

作者：Changmok Oh^a ; Hyuntae Kim^a ; ^b ; Jong Soon Kang^c ; Jieun Yun^c ; Jaejun Sim^d ; Hwan-Mook Kim^d ; Gyoonhee Han^a ; ^b ; ^{gyoonhee@yonsei.ac.kr}

关键词：FLT3 ; Thieno[2 ; 3-d]pyrimidine ; Acute myeloid leukemia (AML) ; Solubility

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

9.D-π-D chromophores based on dithieno[3,2-b:2',3'-d]thiophene (DTT): Potential application in the fabrication of solar cell

作者：Chuan-Zeng Wang^a ; Jung-Hee Do^a ; Tahmina Akther^a ; Xing Feng^b ; Lynne Horsburgh^c ; Mark R.J. Elsegood^c ; Carl Redshaw^d ; Takehiko Yamato^a ; ^{yamatot@cc.saga-u.ac.jp}

关键词：D-π-D chromophores ; Dithieno[3 ; 2-b ; 2' ; 3'-d]thiophene ; Blue fluorescent ; Photo-physical properties ; Density functional theory

刊名：Tetrahedron

出版年：2017

10.Detection of sulfate surface-active substances via fluorescent response using new amphiphilic thiacalix[4]arenes bearing cationic headgroups with Eosin Y dye

作者：V.A. Burilov^a ; ^ultrav@bk.ru ; D.A. Mironova^a ; R.R. Ibragimova^a ; R.I. Nugmanov^a ; S.E. Solovieva^a ; ^b ; I.S. Antipin^a ; ^b

关键词：Thiacalix[4]arenes ; Ammonium compounds ; Macrocyclic ; Amphiphiles ; Fluorescent sensing ; sodium dodecyl sulphate

刊名：Colloids and Surfaces A: Physicochemical and Engineering Aspects

出版年：2017

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