搜索页_+In+vivo+efficacy

常用资源

电子图书

期刊论文

学位会议

在“Elsevier电子期刊”中，命中：7,636条，耗时：0.0589714 秒

在所有数据库中总计命中：47,558条

1.In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation

作者：Jennifer E. Sager^a ; Sasmita Tripathy^a ; Lauren S.L. Price^a ; Abhinav Nath^b ; Justine Chang^c ; Alyssa Stephenson-Famy^c ; Nina Isoherranen^a ; ^ni2@uw.edu

关键词：Drug-drug interactions ; CYP2D6 ; Bupropion ; Enzyme regulation ; In vitro to in vivo extrapolation

刊名：Biochemical Pharmacology

出版年：2017

2.CPX-351 exhibits potent and direct ex vivo cytotoxicity against AML blasts with enhanced efficacy for cells harboring the FLT3-ITD mutation

作者：Max J. Gordon^a ; Paul Tardi^b ; Marc M. Loriaux^c ; ^g ; Stephen E. Spurgeon^d ; ^g ; Elie Traer^d ; ^g ; Tibor Kovacsovics^e ; Lawrence D. Mayer^b ; Jeffrey W. Tyner^f ; ^g ; ^{tynerj@ohsu.edu}

关键词：CPX-351 ; Cytarabine ; Daunorubicin ; Leukemia ; Cytotoxicity

刊名：Leukemia Research

出版年：2017

3.An ex vivo evaluation of the efficacy of andrographolide in modulating differential expression of transcription factors and target genes in periodontal cells and its potential role in treating periodontal diseases

作者：Ambili R^a ; ^{ambiliranjith@yahoo.com} ; Prasanthila Janam^b ; P.S. Saneesh Babu^c ; Manu Prasad^c ; D. Vinod^d ; P.R. Anil Kumar^d ; T.V. Kumary^d ; S. Asha Nair^c ; M. Radhakrishna Pillai^c

关键词：Andrographolide (PubChem CID ; 5318517)

刊名：Journal of Ethnopharmacology

出版年：2017

4.Co-delivery of doxorubicin and interleukin-2 via chitosan based nanoparticles for enhanced antitumor efficacy

作者：Jingjing Wu ; Cui Tang ; Chunhua Yin ; ^{chyin@fudan.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：NN ; N-trimethyl chitosan ; Doxorubicin ; Recombinant ; human ; interleukin-2 ; pH-sensitive modification ; Antitumor efficacy

刊名：Acta Biomaterialia

出版年：2017

5.In vivo study of pomegranate (Punica granatum) peel extract efficacy against Giardia lamblia in infected experimental mice

作者：Wafa Abdullah Al-Megrin ; ^{wafa.megren@gmail.com}

关键词：Pomegranate ; Giardia lamblia ; Swiss albino mice ; Saudi Arabia

刊名：Asian Pacific Journal of Tropical Biomedicine

出版年：2017

6.Safety and efficacy of cardiopoietic stem cells in the treatment of post-infarction left-ventricular dysfunction - From cardioprotection to functional repair in a translational pig infarction model

作者：Maximilian Y. Emmert^a ; ^b ; ^c ; ^d ; ^{maximilian.emmert@usz.ch} ; Petra Wolint^b ; Andras Jakab^e ; Sean P. Sheehy^d ; Francesco S. Pasqualini^c ; ^d ; Thi Dan Linh Nguyen^f ; Monika Hilbe^g ; Burkhardt Seifert^h ; Benedikt Weber^a ; ^d ; Chad E. Brokopp^a ; Dominika Macejovskaⁱ ; Etem Caliskan^b ; Arnold von Eckardstein^j ; Ruth Schwartlander^k ; Viola Vogel^k ; Volkmar Falk^l ; Kevin Kit Parker^d ; Mariann Gyö ; ngyö ; siⁱ ; Simon P. Hoerstrup^a ; ^c ; ^d

关键词：Cardiopoietic stem cell therapy ; Mesenchymal stem cells ; Lineage-specification ; Guided cardiopoiesis ; Post-infarction left-ventricular dysfunction ; Left-ventricular remodeling ; Chronic heart-failure

刊名：Biomaterials

出版年：2017

7.In vitro and in vivo susceptibility of Leishmania major to some medicinal plants

作者：Fatemeh Maleki¹ ; Mitra Zarebavani² ; Mehdi Mohebali³ ; Mohammad Saaid Dayer⁴ ; Fateme Hajialiani⁵ ; Fatemeh Tabatabaie⁵ ; ^{Tabatabaei.f@iums.ac.ir}

关键词：Leishmaniasis ; Glucantime ; Plant extracts ; Mice ; Medicinal plants

刊名：Asian Pacific Journal of Tropical Biomedicine

出版年：2017

8.Psoralen loaded liposomal nanocarriers for improved skin penetration and efficacy of topical PUVA in psoriasis

作者：Sindhu Doppalapudi^a ; Anjali Jain^a ; Dhiraj Kumar Chopra^b ; Wahid Khan^a ; ^{wahid@niperhyd.ac.in}

关键词：Psoralen ; Skin penetration ; Liposomes ; Topical PUVA ; Psoriasis ; Imiquimod induced psoriatic plaque model

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

9.Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo

作者：Kelly L. Warfield^a ; ^{warfieldk@ebsi.com} ; Travis K. Warren^b ; ^{travis.k.warren.ctr@mail.mil} ; Xiangguo Qiu^c ; ^{Xiangguo.qiu@phac-aspc.gc.ca} ; Jay Wells^b ; ^{jay.b.wells.ctr@mail.mil} ; Chad E. Mire^d ; ^{cmire@utmb.edu} ; Joan B. Geisbert^d ; ^{jbgeisbe@utmb.edu} ; Kelly S. Stuthman^b ; ^{Kelly.s.stuthman.ctr@mail.mil} ; Nicole L. Garza^b ; ^{nicole.l.lackemeyer.ctr@mail.mil} ; Sean A. Van Tongeren^b ; ^{sean.a.vantongeren.ctr@mail.mil} ; Amy C. Shurtleff^b ; ^{amy.c.shurtleff.ctr@mail.mil} ; Krystle N. Agans^d ; ^{knagans@utmb.edu} ; Gary Wong^c ; ^e ; ^{garyckwong@hotmail.com} ; Michael V. Callahan^f ; ^g ; ^{mvcallahan@mgh.harvard.edu} ; Thomas W. Geisbert^d ; ^{twgeisbe@utmb.edu} ; Brennan Klose^f ; ^{brennan.klose@abviro.com} ; Urban Ramstedt^f ; ^{urban_ramstedt@yahoo.com} ; Anthony M. Treston^a ; ^{trestona@ebsi.com}

关键词：Iminosugar ; UV-4B ; Ebola virus ; Marburg virus ; Antiviral ; Glucosidase

刊名：Antiviral Research

出版年：2017

10.Efficacy and safety of “Yahom” as a traditional Thai herbal therapy: A systematic review

作者：Krongkarn Chootip^a ; Nathorn Chaiyakunapruk^b ; ^c ; ^d ; ^e ; ^f ; ^h ; Noppamas Soonthornchareonnon^g ; C. Norman Scholfield^b ; ^h ; Anjana Fuangchan^b ; ^{anjanaf@nu.ac.th}

关键词：2-AA ; 2-aminoanthracene ; Ach ; Acetylcholine ; AF2 ; 2-aminofluorene ; Aq ; Aqueous ; BMI ; Body mass index ; BP ; Blood pressure ; BUN ; Blood urea nitrogen ; CYPs ; Cytochromes P450 ; DBP ; Diastolic blood pressure ; DPPH ; 2 ; 2-diphenyl-1-picrylhydrazyl ; ECG ; Electrocardiogram ; FRAP assay ; Ferric reducing antioxidant power assay ; HPLC ; High Performance Liquid Chromatography ; HR ; Heart rate ; IC50 ; Inhibitory concentration that cause 50% inhibition ; ID50 ; Inhibitory dose that cause 50% inhibition ; IP ; Intraperit

刊名：Journal of Ethnopharmacology

出版年：2017

按检索点细分(7636)

题名(461)

关键词(58)

文摘(6661)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700