搜索页_+Knock-in+HD+mice

常用资源

电子图书

期刊论文

学位会议

在“Elsevier电子期刊”中，命中：141条，耗时：0.0279857 秒

在所有数据库中总计命中：4,708条

1.Erectile Dysfunction in Heme-Deficient Nitric Oxide-Unresponsive Soluble Guanylate Cyclase Knock-In Mice

作者：Kelly Decaluwé ; PhD¹ ; Bart Pauwels ; PhD¹ ; Charlotte Boydens ; MSc¹ ; Robrecht Thoonen ; PhD² ; Emmanuel S. Buys ; PhD³ ; Peter Brouckaert ; PhD⁴ ; ⁵ ; Johan Van de Voorde ; PhD¹ ; ^{johan.vandevoorde@UGent.be}

关键词：Soluble Guanylate Cyclase ; Apo-sGC ; Erectile Dysfunction ; Oxidative Stress ; Soluble Guanylate Cyclase Activators ; Soluble Guanylate Cyclase Stimulators

刊名：The Journal of Sexual Medicine

出版年：2017

2.Histone deacetylases 3 deletion restrains PM2.5-induced mice lung injury by regulating NF-κB and TGF-β/Smad2/3 signaling pathways

作者：Li-Zhi Gu^a ; ^{yu197301@yeah.net} ; Hong Sun^a ; Jian-Hui Chen^b

关键词：Acute lung injury ; PM2.5 ; HDAC 3 ; TGF-β/Smad ; TLR4/NF-κB

刊名：Biomedicine & Pharmacotherapy

出版年：2017

3.Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice

作者：Mahalakshmi Shankaran^a ; Eleonora Di Paolo^b ; Valerio Leoni^c ; ^d ; Claudio Caccia^c ; Costanza Ferrari Bardile^b ; Hussein Mohammed^a ; Stefano Di Donato^c ; ¹ ; Seung Kwak^e ; Deanna Marchionini^e ; Scott Turner^a ; Elena Cattaneo^b ; ^{elena.cattaneo@unimi.it} ; Marta Valenza^b ; ^{marta.valenza@unimi.it}

关键词：Huntington ; Brain cholesterol ; Lathosterol ; Striatum

刊名：Neurobiology of Disease

出版年：2017

4.MMP-13 is one of the critical mediators of the effect of HDAC4 deletion on the skeleton

作者：Teruyo Nakatani ; Tiffany Chen ; Nicola C. Partridge ; ^{ncp234@nyu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：TRAP ; tartrate-acid resistant acid phosphatase ; Runx2 ; Runt-related transcription factor 2 ; Mmp13 ; matrix metalloproteinase-13 ; Hdac4 ; histone deacetylase 4

刊名：Bone

出版年：2016

5.Progressive gene dose-dependent disruption of the methamphetamine-sensitive circadian oscillator-driven rhythms in a knock-in mouse model of Huntington's disease

作者：Koliane Ouk ^{ko303@cam.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Juliet Aungier ^{ja448@cam.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; A. Jennifer Morton ; ^{ajm41@cam.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：ANOVA ; analysis of variance ; DA ; dopamine ; DD ; constant darkness ; HD ; Huntington's disease ; HET ; heterozygous ; HOM ; homozygous ; HTT ; human Huntingtin gene ; LD ; 12 ; 12 light-dark ; MAP ; methamphetamine ; MASCO ; methamphetamine-sensitive circadian oscillator ; SCN ; suprachiasmatic nucleus ; WT ; wild-type

刊名：Experimental Neurology

出版年：2016

6.The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease

作者：Emma Yhnell ; ^{YhnellE@cf.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Stephen B. Dunnett ; Simon P. Brooks

关键词：Huntington's disease ; Operant tests ; 9-Hole box ; Reversal learning ; Short-term memory ; HD mice

刊名：Journal of Neuroscience Methods

出版年：2016

7.Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner

作者：Lexiao Li ; Pamela Saliba ; Stefan Reischl ; Hugo H. Marti ; Reiner Kunze ; ^{reiner.kunze@physiologie.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author}

关键词：BBB ; blood-brain barrier ; GFAP ; glial fibrillary acidic protein ; HIF ; hypoxia inducible factor ; KO ; knockout ; MCAO ; middle cerebral artery occlusion ; PHD ; prolyl 4-hydroxylase domain protein ; ROI ; region of interest ; WT ; wild-type ; SVZ ; subventricular zone ; VEGF ; vascular endothelial growth factor

刊名：Neurobiology of Disease

出版年：2016

8.In situ enzymatic activity of transglutaminase isoforms on brain tissue sections of rodents: A new approach to monitor differences in post-translational protein modifications during neurodegeneration

作者：Anja Schulze-Krebs^a ; ^{Anja.Schulze-Krebs@uk-erlangen.de" class="auth_mail" title="E-mail the corresponding author} ; Fabio Canneva^a ; Rebecca Schnepf^a ; Julia Dobner^a ; Walburga Dieterich^b ; Stephan von Hö ; rsten^a

关键词：Aca ; epsilon-aminocaprionic acid ; AD ; Alzheimer׳s disease ; BACHD ; Bacterial artificial chromosome Huntington׳s disease transgenic mice ; cc ; corpus callosum ; CPu (striatum) ; caudate putamen ; cx ; cortex ; HD ; Huntington׳s disease ; dcw ; deep cerebral white matter ; E ; ependym ; FITC ; fluorescein isothiocyanate ; GGEL ; Nε(γ-L-glutamyl)-L-lysine ; Hip ; hippocampus ; (m)HTT ; (mutated) huntingtin ; IHC ; immunohistochemistry ; ko ; knock out ; LS ; lateral septum ; LV ; lateral ventricle ; PD ; Parkinson׳s disease ; RT

刊名：Brain Research

出版年：2016

9.Altered expression of retinoblastoma 1 in Hirschsprung's disease

作者：Anne Marie O'Donnell ; David Coyle ; Prem Puri ; ^{prem.puri@ncrc.ie" class="auth_mail" title="E-mail the corresponding author}

关键词：Retinoblastoma 1 ; Enteric nervous ; Hirschsprung's disease ; Colonic aganglionosis

刊名：Journal of Pediatric Surgery

出版年：2016

10.Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain

作者：Emma Leishman^a ; Ken Mackie^a ; ^b ; Serge Luquet^c ; Heather B. Bradshaw^a ; ^{hbbradsh@indiana.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：2-AG ; 2-arachidonyl glycerol ; 2-LG ; 2-linoleoyl glycerol ; ABHD4 ; α/β-hydrolase domain 4 ; AEA ; N-arachidonoyl ethanolamine (anandamide) ; A-Taur ; N-arachidonoyl taurine ; CER ; cerebellum ; COX ; cyclooxygenase ; CTX ; cortex ; DEA ; N-docosahexaenoyl ethanolamine ; eCB ; endogenous cannabinoid ; FAAH ; fatty acid amide hydrolase ; GABA ; gamma-amino butyric acid ; GDE1 ; glycerophosphodiesterase 1 ; HIPP ; hippocampus ; HYP ; hypothalamus ; KO ; knockout ; LEA ; N-linoleoyl ethanolamine ; MAGL ; monoacylglycerol lipase ; M

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2016

按检索点细分(141)

题名(6)

关键词(6)

文摘(103)

按出版年细分(141)

2027年及以后(10)

2017年(3)

2016年(11)

2015年(3)

2013年(15)

2012年(29)

2011年(12)

2010年(7)

2009年(10)

2008年(4)

2007年(8)

2006年(8)

2005年(2)

2004年(2)

2003年(3)

2002年(6)

2001年(1)

2000年(2)

2000年及以前(5)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700