搜索页_+LXR+agonists

设为首页

收藏本站

网站地图 | English | 公务邮箱

远程访问

NSTL服务站

常用资源

在“Elsevier电子期刊”中，命中：135条，耗时：小于0.01 秒

在所有数据库中总计命中：617条

1.LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway

作者：Jing-zhong Wang ; ^{jingzhongwang1@sina.cn} ; Yan Fang ; Wei-dong Ji ; Hui Xu

关键词：Neural progenitor cells ; Proliferation ; LXR agonists ; GW3965 ; LXR623

刊名：Biochemical and Biophysical Research Communications

出版年：2017

2.The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism

作者：Jonathan Matalonga¹ ; Estibaliz Glaria¹ ; Mariana Bresque² ; Carlos Escande² ; José ; Marí ; a Carbó ; ¹ ; Kerstin Kiefer³ ; Ruben Vicente³ ; Theresa E. Leó ; n¹ ; Susana Beceiro⁴ ; Mó ; nica Pascual-Garcí ; a¹ ; Joan Serret⁵ ; Lucí ; a Sanjurjo⁶ ; Samantha Moró ; n-Ros¹ ; Antoni Riera⁷ ; ⁸ ; Sonia Paytubi⁹ ; Antonio Juarez⁹ ; ¹⁰ ; Fernando Sotillo⁷ ; Lennart Lindbom¹¹ ; Carme Caelles¹² ; Maria-Rosa Sarrias⁶ ; Jaime Sancho¹³ ; Antonio Castrillo⁴ ; Eduardo N. Chini¹⁴ ; Annabel F. Valledor¹ ; ¹⁵ ; ^{afernandezvalledor@ub.edu}

关键词：macrophage ; nuclear receptor ; LXR ; bacterial infection ; NAD ; cytoskeleton ; CD38

刊名：Cell Reports

出版年：2017

3.Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core

作者：Colin M. Tice ; Paul B. Noto ; Kristi Yi Fan ; Wei Zhao ; Stephen D. Lotesta ; Chengguo Dong ; Andrew P. Marcus ; Ya-Jun Zheng ; Guozhou Chen ; Zhongren Wu ; Rebecca Van Orden ; Jing Zhou ; Yuri Bukhtiyarov ; Yi Zhao ; Kerri Lipinski ; Lamont Howard ; Joan Guo ; Geeta Kandpal ; Shi Meng ; Andrew Hardy ; Paula Krosky ; Richard E. Gregg ; Katerina Leftheris ; Brian M. McKeever ; Suresh B. Singh ; Deepak Lala ; Gerard M. McGeehan ; Linghang Zhuang ; David A. Claremon

关键词：LXR ; Structure-based drug design ; Alzheimer&rsquo ; s disease ; Brain

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

4.E17110 promotes reverse cholesterol transport with liver X receptor β agonist activity in vitro

作者：Ni Li^a ; ^b ; Xiao Wang^b ; Peng Liu^b ; Duo Lu^a ; Wei Jiang^b ; Yanni Xu^b ; ^{xuyanniwendeng@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Shuyi Si^b ; ^{sisyimb@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ABCA1 ; ATP-binding cassette transporter A1 ; ABCG1 ; ATP-binding cassette transporter G1 ; ApoA-I ; apolipoprotein A-I ; GAPDH ; glyceraldehyde-phosphate dehydrogenase ; HDL ; high-density lipoprotein ; LBD ; ligand-binding domain ; LXR ; liver X receptor ; LXRE ; LXR response element ; NR ; nuclear receptor ; ox-LDL ; oxidized low-density lipoprotein ; RCT ; reverse cholesterol transport ; RXR ; retinoid X receptor

刊名：Acta Pharmaceutica Sinica B

出版年：2016

5.Liver X Receptor Regulates Triglyceride Absorption Through Intestinal Down-regulation of Scavenger Receptor Class B, Type 1

作者：Olivier Briand¹ ; Vé ; ronique Touche¹ ; Sophie Colin¹ ; Gemma Brufau² ; Alberto Davalos³ ; Marleen Schonewille² ; Fabiola Bovenga⁴ ; Vé ; ronique Carriè ; re⁶ ; ⁷ ; ⁸ ; Jan Freark de Boer² ; Camille Dugardin¹ ; Bé ; atrice Riveau⁵ ; ⁶ ; ⁷ ; Vé ; ronique Clavey¹ ; Anne Tailleux¹ ; Antonio Moschetta⁴ ; Miguel A. Lasunció ; n⁸ ; ⁹ ; Albert K. Groen² ; Bart Staels¹ ; ^{bart.staels@pasteur-lille.fr" class="auth_mail" title="E-mail the corresponding author} ; Sophie Lestavel¹

关键词：Hypertriglyceridemia ; Lipid-Sensing ; Fat Absorption ; Triglyceride-Rich Lipoproteins

刊名：Gastroenterology

出版年：2016

6.Protective effects of retinoid x receptors on retina pigment epithelium cells

作者：Victoria Belé ; n Ayala-Peña ; Fiorella Pilotti ; Yanel Volonté ; Nora P. Rotstein ; Luis E. Politi ; Olga Lorena German ; ^{olgerman@criba.edu.ar" class="auth_mail" title="E-mail the corresponding author}

关键词：AMD ; age-related macular degeneration ; RPE ; retina pigment epithelium cells ; ROS ; reactive oxygen species ; PUFA ; polyunsaturated fatty acids ; DHA ; docosahexaenoic acid ; RXRs ; retinoid x receptors ; PPAR ; peroxisome proliferator-activated receptor ; LXR ; liver X receptor ; RAR ; Retinoic acid receptor ; Bclxl ; B-cell lymphoma-extra large ; Bcl-2 ; B-cell lymphoma-2 ; Bax ; Bcl-2-associated X protein ; NFκB ; nuclear factor kB ; RA ; retinoic acid ; H2O2 ; hydrogen peroxide ; DMEM ; Dulbecco's modified Eagle's med

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

7.A selective peroxisome proliferator-activated receptor δ agonist PYPEP suppresses atherosclerosis in association with improvement of the serum lipoprotein profiles in human apolipoprotein B100 and cholesteryl ester transfer protein double transgenic mice

作者：Noriyuki Naya ; ^{noriyuki.naya@shionogi.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Keita Fukao ; Akemi Nakamura ; Tadateru Hamada ; Masayuki Sugimoto¹ ; Midori Kojima ; Norito Yoshimura ; Ken-Ichiro Uwabe ; Keiichi Imagawa ; Kohji Nomura² ; Seijiro Hara³ ; Toru Nakano³ ; Takanori Iwasaki ; Toshihiro Shinosaki⁴ ; Kohji Hanasaki⁴

关键词：PPAR ; peroxisome proliferator-activated receptor ; CETP ; cholesteryl ester transfer protein ; hApoB100/hCETP-dTg ; human apolipoprotein B100 and human cholesteryl ester transfer protein double transgenic ; HDL ; high-density lipoprotein ; LDL ; low-density lipoprotein ; VLDL ; very low-density lipoprotein ; ApoA-I ; apolipoprotein A-I ; MCP-1 ; macrophage chemoattractant protein-1 ; LXR ; Liver X receptor ; RXRα ; retinoid X receptor ; RARα ; retinoic acid receptor alpha ; TRβ ; thyroid hormone receptor beta ; FXR ; f

刊名：Metabolism

出版年：2016

8.Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR

作者：Linara Gabitova¹ ; ⁷ ; Diana Restifo¹ ; Andrey Gorin¹ ; ⁷ ; Kunal Manocha¹ ; Elizabeth Handorf² ; Dong-Hua Yang¹ ; Kathy Q. Cai³ ; ⁴ ; Andres J. Klein-Szanto³ ; ⁴ ; David Cunningham⁵ ; Lisa E. Kratz⁶ ; Gail E. Herman⁵ ; Erica A. Golemis¹ ; Igor Astsaturov¹ ; ⁷ ; ^{igor.astsaturov@fccc.edu" class="auth_mail" title="E-mail the corresponding author}

刊名：Cell Reports

出版年：2015

9.Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol

作者：O. Alex ; er H. 脜str ; Marcel S ; berg ; Ingebrigt Sylte ; Carl Henrik G枚rbitz ; G. Hege Thoresen ; Eili T. Kase ; P氓l Rongved

关键词：Liver X receptor agonists ; Molecular modeling ; New chemical entities ; SAR ; Gene regulation

刊名：Bioorganic and Medicinal Chemistry

出版年：1 January, 2014

10.Structure-activity relationship-guided development of retinoic acid receptor-related orphan receptor gamma (ROR纬)-selective inverse agonists with a phenanthridin-6(5H)-one skeleton from a liver X receptor ligand

作者：Yuko Nishiyama^a ; Masahiko Nakamura^a ; Takashi Misawa^a ; Madoka Nakagomi^b ; Makoto Makishima^c ; Minoru Ishikawa^a ; ^{m-ishikawa@iam.u-tokyo.ac.jp" class="auth_mail} ; Yuichi Hashimoto^a

关键词：ROR ; Phenanthridinone ; Inverse agonist ; LXR

刊名：Bioorganic and Medicinal Chemistry

出版年：1 May, 2014

按检索点细分(135)

题名(22)

关键词(6)

文摘(107)

按出版年细分(135)

2027年及以后(1)

2017年(2)

2016年(5)

2015年(1)

2013年(9)

2012年(13)

2011年(11)

2010年(20)

2009年(17)

2008年(11)

2007年(10)

2006年(9)

2005年(7)

2004年(1)

2003年(5)

2002年(3)

2001年(4)

2000年及以前(6)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700