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在“Elsevier电子期刊”中，命中：28条，耗时：0.0199905 秒

在所有数据库中总计命中：392条

1.Alterations in glucose metabolism proteins responsible for the Warburg effect in esophageal squamous cell carcinoma

关键词：Esophageal cancer ; Warburg effect ; Pyruvate kinase M2 ; GLUT-1 ; Hexokinase 2 ; HIF-1α

刊名：Experimental and Molecular Pathology

出版年：2016

2.Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans

作者：Lei Li¹ ; ² ; ^&dagger ; ; Giulia M. Pilo³ ; ^&dagger ; ; Xiaolei Li² ; ⁴ ; ^&dagger ; ; Antonio Cigliano⁵ ; Gavinella Latte³ ; Li Che² ; Christy Joseph⁵ ; Marta Mela³ ; Chunmei Wang² ; Lijie Jiang² ; Silvia Ribback⁵ ; Maria M. Simile³ ; Rosa M. Pascale³ ; Frank Dombrowski⁵ ; Matthias Evert⁵ ; Clay F. Semenkovich⁶ ; Xin Chen² ; Diego F. Calvisi³ ; ^{calvisid@uniss.it" class="auth_mail" title="E-mail the corresponding author}

关键词：ACAC ; acetyl-CoA carboxylase ; ACLY ; adenosine triphosphate citrate lyase ; AKT ; v-akt murine thymoma viral oncogene homolog ; ELOVL5 ; elongation of very long chain fatty acids protein 5 ; FASN ; fatty acid synthase ; HCC ; hepatocellular carcinoma ; LDH ; lactate dehydrogenase ; mTOR ; mammalian target of rapamycin ; mTORC ; mTOR complex ; N-Ras ; neuroblastoma Ras viral oncogene homolog ; PKM2 ; pyruvate kinase M2 isoform ; Raptor ; regulatory-associated protein of mTOR ; Rictor ; rapamycin-insensitive companion o

刊名：Journal of Hepatology

出版年：2016

3.Pyruvate kinase: Function, regulation and role in cancer

作者：William J. Israelsen^a ; ¹ ; ^{william.israelsen@utsouthwestern.edu" class="auth_mail" title="E-mail the corresponding author} ; Matthew G. Vander Heiden^a ; ^b ; ^{mvh@mit.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Cancer metabolism ; Pyruvate kinase ; PKM2

刊名：Seminars in Cell & Developmental Biology

出版年：2015

4.Comparison of liver microRNA transcriptomes of Tibetan and Yorkshire pigs by deep sequencing

作者：Yanyue Li^a ; ¹ ; Xiaocheng Li^d ; ¹ ; Wen-kui Sun^a ; ^b ; ¹ ; Chi Cheng^a ; ^c ; ¹ ; Yi-hui Chen^a ; Kai Zeng^d ; Xiaohui Chen^d ; Yiren Gu^d ; Rong Gao^a ; ^{gaorong96@163.com" class="auth_mail" title="E-mail the corresponding author} ; Rui Liu^d ; ^{liuruicau@126.com" class="auth_mail" title="E-mail the corresponding author} ; Xuebin Lv^d ; ^{lvxuebin@21cn.com" class="auth_mail" title="E-mail the corresponding author}

关键词：miRNA ; microRNA ; TPL ; Tibetan pig liver ; YKL ; Yorkshire pig liver ; qPCR ; quantitative real-time PCR ; Stem&ndash ; loop qPCR ; stem&ndash ; loop quantitative real-time PCR ; Sirt1 ; Sirtuin type 1 ; PKM2 ; M2 isoform of pyruvate kinase ; LXRα ; Liver X receptor α ; SR-BI ; scavenger receptor class B type I

刊名：Gene

出版年：2016

5.Proteomic identification of predictive tissue biomarkers of sensitive to neoadjuvant chemotherapy in squamous cervical cancer

作者：Lu Guo^a ; Caixia Zhang^b ; Jinghong Zhu^b ; Yuqin Yang^c ; Jianfa Lan^d ; Gang Su^a ; Xiaodong Xie^a ; ^{xdxie@lzu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Squamous cervical cancer ; Neoadjuvant chemotherapy ; Proteomics ; Drug sensitivity

刊名：Life Sciences

出版年：2016

6.Pyruvate kinase isoform M2 (PKM2) participates in multiple myeloma cell proliferation, adhesion and chemoresistance

作者：Yunhua He^a ; ¹ ; Yuchan Wang^a ; ¹ ; Hong Liu^b ; Xiaohong Xu^d ; Song He^c ; Jie Tang^a ; Yuejiao Huang^c ; Xiaobing Miao^c ; Yaxun Wu^c ; Qiru Wang^a ; Chun Cheng^a ; ^{ntchengchun@sina.com" class="auth_mail" title="E-mail the corresponding author}

关键词：PKM2 ; MM ; Proliferation ; CAM-DR ; PI3K/Akt ; MAPK/ERK

刊名：Leukemia Research

出版年：2015

7.Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2)

作者：Yong Xu ; Xiao-Hui Liu ; Michael Saunders ; Scott Pearce ; Jason M. Foulks ; K. Mark Parnell ; Adrianne Clifford ; Rebecca N. Nix ; Jeremy Bullough ; Thomas F. Hendrickson ; Kevin Wright ; Michael V. McCullar ; Steven B. Kanner ; Koc-Kan Ho

关键词：Pyruvate kinase M2 ; PKM2 activator ; 3-(Trifluoromethyl)-1H-pyrazole-5-carboxamides ; Bioisostere ; Cancer metabolism

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：15 January, 2014

8.Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators

作者：Chuangxing Guo ; Angelica Linton ; Mehran Jalaie ; Susan Kephart ; Martha Ornelas ; Mason Pairish ; Samantha Greasley ; Paul Richardson ; Karen Maegley ; Michael Hickey ; John Li ; Xin Wu ; Xiaodong Ji ; Zhi Xie

关键词：M2 isoform of pyruvate kinase ; PKM2 ; PKM2 activator ; PKM2 activation ; PKM1 ; Cancer metabolism ; Warburg effect ; Anti-tumor ; Anti-cancer

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2013

9.1-(sulfonyl)-5-(arylsulfonyl)indoline as activators of the tumor cell specific M2 isoform of pyruvate kinase

作者：Avihai Yacovan ; Rachel Ozeri ; Tzofit Kehat ; Sima Mirilashvili ; Daniel Sherman ; Alex Aizikovich ; Alina Shitrit ; Efrat Ben-Zeev ; Nili Schutz ; Osnat Bohana-Kashtan ; Alex ; er Konson ; Vered Behar ; Oren M. Becker

关键词：PKM2 ; Pyruvate kinase ; Cellular metabolism ; Anti-cancer strategies ; Small molecule activators

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

10.Vitamin K₃ and K₅ are inhibitors of tumor pyruvate kinase M2

作者：Jing Chen^a ; ^b ; Zheng Jiang^c ; Beibei Wang^a ; ^b ; Yanguang Wang^c ; Xun Hu^a ; ^b ; ^{huxun@zju.edu.cn}

关键词：Vitamin K3 ; Vitamin K5 ; Pyruvate kinase M2 ; Inhibitor ; Glycolysis

刊名：Cancer Letters

出版年：2012

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