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在“Elsevier电子期刊”中，命中：49条，耗时：小于0.01 秒

1.Inhibition of OCT2, MATE1 and MATE2-K as a possible mechanism of drug interaction between pazopanib and cisplatin

作者：C. Sauzay^a ; ^b ; M. White-Koning^b ; I. Hennebelle^a ; ^b ; T. Deluche^a ; ^b ; C. Delmas^a ; ^b ; D.C. Imbs^a ; ^b ; E. Chatelut^a ; ^b ; F. Thomas^a ; ^b ; ^{thomas.fabienne@iuct-oncopole.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：OCT2 ; organic cation transporter 2 ; MATE ; multidrug and toxin extrusion ; OATP ; organic anion transporting polypeptide ; TKI ; tyrosine kinase inhibitors ; EV ; empty vector ; ASP+ ; 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide ; DDI ; drug&ndash ; drug interaction ; VEGFR ; vascular endothelial growth factor receptor ; PDGFR ; platelet-derived growth factor receptor ; ABCB1 ; ATP-binding cassette sub-family B member 1 ; ABCG2 ; ATP-binding cassette protein G2 ; CYP ; cytochrome P450 ; Km ; Michaelis-Menten c

刊名：Pharmacological Research

出版年：2016

2.The transporter and permeability interactions of asymmetric dimethylarginine (ADMA) and L-arginine with the human blood-brain barrier in vitro

作者：Christopher P. Watson^a ; Evangelos Pazarentzos^b ; Mehmet Fidanboylu^a ; Beatriz Padilla^a ; Rachel Brown^a ; Sarah A. Thomas^a ; ^{sarah.thomas@kcl.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：ADMA ; asymmetric dimethylarginine ; BBB ; blood-brain barrier ; CAA ; cationic amino acids ; CAT-1 ; cationic amino acid transporter 1 ; DDAH ; NG ; NG-dimethylarginine dimethylaminohydrolase ; GTPases ; guanosine triphosphatases ; IFN-γ ; interferon gamma ; LAT ; large neutral amino acid transporters ; L-NIO ; N-iminoethyl-L-ornithine ; MATE1 ; multidrug and toxin exclusion protein 1 ; NO ; nitric oxide ; NOS ; nitric oxide synthase ; OCT ; organic cation transporter ; OSPC ; octanol-saline partition coefficient ; PRMTs

刊名：Brain Research

出版年：2016

3.Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics

作者：David J. Wagner ^{davidwag@uw.edu" class="auth_mail" title="E-mail the corresponding author} ; Tao Hu ^{taohu85@uw.edu" class="auth_mail" title="E-mail the corresponding author} ; Joanne Wang ; ^{jowang@uw.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Intracellular drug concentration ; Pharmacodynamics ; OCT ; MATE ; PMAT ; Drug transporter

刊名：Pharmacological Research

出版年：2016

4.ABC transporters and xenobiotic defense systems in early life stages of rainbow trout (Oncorhynchus mykiss)

作者：Christian Kropf^a ; ^b ; ^c ; Helmut Segner^b ; Karl Fent^a ; ^d ; ^{karl.fent@fhnw.ch" class="auth_mail" title="E-mail the corresponding author} ; ^{karl.fent@bluewin.ch" class="auth_mail" title="E-mail the corresponding author}

关键词：ABC transporter ; Biotransformation ; Yolk sac ; Solute carriers ; Early life stage ; Oncorhynchus mykiss

刊名：Comparative Biochemistry and Physiology, Part C

出版年：2016

5.The effects of rabeprazole on metformin pharmacokinetics and pharmacodynamics in Chinese healthy volunteers

作者：Guojing Liu^a ; ^b ; ¹ ; Jiagen Wen^a ; ^b ; ¹ ; Dong Guo^a ; Zhenmin Wang^a ; Xiaolei Hu^a ; Jie Tang^a ; Zhaoqian Liu^a ; ^b ; Honghao Zhou^a ; ^b ; Wei Zhang^a ; ^b ; ^{yjsd2003@163.com}

关键词：Rabeprazole ; Metformin ; Transporter ; Pharmacokinetics ; Pharmacodynamics

刊名：Journal of Pharmacological Sciences

出版年：2016

6.Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate

作者：Katia Sayyed^a ; ^b ; Marc Le Vee^a ; Ziad Abdel-Razzak^b ; Elodie Jouan^a ; Bruno Stieger^c ; Claire Denizot^d ; Yannick Parmentier^d ; Olivier Fardel^a ; ^e ; ^{olivier.fardel@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：ABC ; ATP-binding cassette ; AhR ; aryl hydrocarbon receptor ; ALDH3A1 ; aldehyde deshydrogenase 3A1 ; BCRP ; breast cancer resistance protein ; BSEP ; bile salt export pump ; BSP ; bromosulfophtalein ; CCK8 ; cholecystokinin octapeptide sulphated ; CF ; carboxy-2.7-dichlorofluorescein ; CSC ; cigarette smoke condensate ; CYP ; cytochrome P-450 ; DMEM ; Dulbecco&rsquo ; s modified Eagle medium ; DMSO ; dimethyl sulfoxide ; E3S ; estrone-3-sulfate ; EC50 ; half maximal effective concentration ; IC50 ; half maximal inhibitory c

刊名：Toxicology

出版年：2016

7.Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions

关键词：AUC ; area under the plasma concentration-time curve ; B/P ; blood-to-plasma ratio ; CYP ; cytochrome P450 ; CLint ; intrinsic clearance ; Cmax ; maximum plasma concentration ; CLPD ; passive permeability-surface area product ; DDI ; drug&ndash ; drug interaction ; fa ; fraction absorbed ; Jmax ; maximum rate of active transport ; JOCT1 ; rate of OCT1 transport ; JOCT2 ; rate of OCT2 transport ; ka ; absorption rate constant ; Ki ; inhibition constant ; Km ; Michaelis constant ; Kp ; tissue to plasma partition coefficient ; MA

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

8.Identification and functional characterization of novel MATE1 genetic variations in Koreans

作者：Tae Hee Kim¹ ; Kyoung Hee Kim¹ ; Hyo Jin Park ; Siyoon Kim ; Ji Ha Choi ; ^{jihachoi@ewha.ac.kr}

关键词：MATE1 ; Haplotype ; Promoter ; Nkx-2.5 ; SREBP-1 ; USF-1

刊名：Biochemical and Biophysical Research Communications

出版年：2013

9.Renal tubular secretion of pramipexole

作者：Jana Knop^a ; Eva Hoier^a ; Thomas Ebner^b ; Martin F. Fromm^a ; ^{martin.fromm@fau.de" class="auth_mail" title="E-mail the corresponding author} ; Fabian Mü ; ller^a ; ¹

关键词：MATE ; OCT2 ; Cimetidine ; Drug transport ; MDCK

刊名：European Journal of Pharmaceutical Sciences

出版年：2015

10.The synthesis and biodistribution of [¹¹C]metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1) in vivo

作者：W. Ewan Hume ; Tomotaka Shingaki ; Tadayuki Takashima ; Yoshinobu Hashizume ; Takashi Okauchi ; Yumiko Katayama ; Emi Hayashinaka ; Yasuhiro Wada ; Hiroyuki Kusuhara ; Yuichi Sugiyama ; Yasuyoshi Watanabe

关键词：Positron emission tomography (PET) ; Metformin ; Multi-drug and toxin extrusion transporter 1 (MATE1) ; Hepatobiliary transport ; Pyrimethamine

刊名：Bioorganic and Medicinal Chemistry

出版年：15 December, 2013

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