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在“Elsevier电子期刊”中，命中：189条，耗时：小于0.01 秒

1.Lack of genetic association between OCT1, ABCB1, and UGT2B7 variants and morphine pharmacokinetics

作者：LM Nielsen^a ; ^b ; ¹ ; E Sverrisdó ; ttir^b ; ¹ ; TB Stage^c ; S Feddersen^d ; K Brø ; sen^c ; LL Christrup^b ; AM Drewes^a ; ^e ; AE Olesen^a ; ^b ; ^e ; ^aneso@rn.dk

关键词：Morphine ; Interindividual variability ; Pharmacokinetics ; Pharmacogenetics ; Healthy volunteers

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.Para-aminosalicylic acid (PAS) characterized as a substrate of OCT1 and OCT2 and OAT1 and OAT3 transporter and OCT1/2 polymorphism effect, in vitro

作者：M.D. Masud Parvez¹ ; Jin-Ah Jung² ; Ho Jung Shin¹ ; Nazia Kaisar¹ ; M.D. Hasanuzzaman¹ ; Dong-Hyun Kim¹ ; Jae-Gook Shin¹ ; ²

刊名：Drug Metabolism and Pharmacokinetics

出版年：2017

3.Effects of frequently used pharmaceutical excipients on the organic cation transporters 1-3 and peptide transporters 1/2 stably expressed in MDCKII cells

作者：Marcus Otter ; Stefan Oswald ; Werner Siegmund ; Markus Keiser ; ^{markus.keiser@uni-greifswald.de}

关键词：Pharmaceutical excipients ; Solubilizing agents ; Drug transporter ; Uptake transport ; Organic cation transporter (OCT) ; Peptide transporter (PEPT) ; Polyethylene glycol (PEG) ; Hydroxypropyl-β-cyclodextrin ; Solutol HS 15 (macrogol 15 hydroxystearate ; polyoxyl 15 hydroxystearate) ; Cremophor ; Tween (polysorbate) ; Kolliphor (poloxamer) ; MDCK cells ; In vitro ; Cell model ; Competition assay ; Inhibition assay

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

4.Specific OCT1 and ABCG2 polymorphisms are associated with Lamotrigine concentrations in Chinese patients with epilepsy

作者：Chun-Hong Shen ; Yin-Xi Zhang ; Ru-Yi Lu ; Bo Jin ; Shan Wang ; Zhi-Rong Liu ; Ye-Lei Tang ; Mei-Ping Ding ; ^{meipingd@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Lamotrigine ; Pharmacogenetics ; OCT1 ; ABCG2 ; ABCC2 ; HNF4α

刊名：Epilepsy Research

出版年：2016

5.Low ABCB1 and high OCT1 levels play a favorable role in the molecular response to imatinib in CML patients in the community clinical practice

作者：Flavia da Cunha Vasconcelos^a ; Marcos Antonio Mauricio Scheiner^a ; Arthur Moellman-Coelho^b ; André ; Luiz Mencalha^c ; Ilana Zalcberg Renault^d ; Vivian Mary Rumjanek^e ; Raquel Ciuvalschi Maia ; MD ; PhD^a ; ^b ; ^{rcmaia@inca.gov.br} ; ^{rcm@unisys.com.br}

关键词：Chronic myeloid leukemia ; Imatinib ; Sokal score ; ABCB1/P-glycoprotein ; ABCG2 ; OCT1

刊名：Leukemia Research

出版年：2016

6.The Oct1 transcription factor and epithelial malignancies: Old protein learns new tricks

作者：Karina Vá ; zquez-Arreguín ; Dean Tantin ; ^{dean.tantin@path.utah.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Oct1/POU2F1 ; NuRD ; Jmjd1a/KDM3A ; Gastric cancer ; Cervical cancer ; Breast cancer ; Colorectal cancer ; Prostate cancer ; Lung adenocarcinoma ; Thyroid cancer

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2016

7.Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions

关键词：AUC ; area under the plasma concentration-time curve ; B/P ; blood-to-plasma ratio ; CYP ; cytochrome P450 ; CLint ; intrinsic clearance ; Cmax ; maximum plasma concentration ; CLPD ; passive permeability-surface area product ; DDI ; drug&ndash ; drug interaction ; fa ; fraction absorbed ; Jmax ; maximum rate of active transport ; JOCT1 ; rate of OCT1 transport ; JOCT2 ; rate of OCT2 transport ; ka ; absorption rate constant ; Ki ; inhibition constant ; Km ; Michaelis constant ; Kp ; tissue to plasma partition coefficient ; MA

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

8.Trospium chloride is absorbed from two intestinal “absorption windows” with different permeability in healthy subjects

作者：Tobias Tadken^a ; Michael Weiss^b ; Christiane Modess^a ; Danilo Wegner^a ; Tarek Roustom^a ; Claudia Neumeister^c ; Ulrich Schwantes^c ; Hans-Ulrich Schulz^d ; Werner Weitschies^e ; Prof. Dr. Werner Siegmund^a ; ^{werner.siegmund@uni-greifswald.de}

关键词：Trospium chloride ; Pharmacokinetics ; Gastric infusion ; Food effects ; P-glycoprotein ; OCT1

刊名：International Journal of Pharmaceutics

出版年：2016

9.Genetic variations of hOCT1 gene and CYP3A4/A5 genes and their association with imatinib response in Chronic Myeloid Leukemia

作者：Shantashri Vaidya^a ; Kanjaksha Ghosh^a ; Chandrakala Shanmukhaiah^b ; Babu Rao Vundinti^a ; ^{vbaburao@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：CML ; Chronic Myeloid Leukemia ; CP ; chronic phase ; CCyR ; Complete Cytogenetic Response ; MMR ; Major Molecular Response ; MCyR ; Major Cytogenetic Response ; CHR ; Complete Haematological Response ; SNP ; single nucleotide polymorphism ; hOCT1 ; human organic cation transporter 1 ; TKI ; tyrosine kinase inhibitor

刊名：European Journal of Pharmacology

出版年：2015

10.Organic cation rhodamines for screening organic cation transporters in early stages of drug development

作者：Malachy C. Ugwu^a ; ^b ; ¹ ; Angus Oli^a ; ^b ; ¹ ; Charles O. Esimone^b ; Remigius U. Agu^a ; ^{Remigius.agu@dal.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：Organic cation transporters (OCT1&ndash ; 3) ; Carnitine/organic cation transporter (OCTN1 ; OCTN2) ; Rhodamines ; Calu-3 cells ; Fluorescence

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

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