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在“Elsevier电子期刊”中，命中：1,652条，耗时：0.0190224 秒

在所有数据库中总计命中：11,483条

1.Replacing the terminal piperidine in ceritinib with aliphatic amines confers activities against crizotinib-resistant mutants including G1202R

作者：Gangadhar Rao Mathi^a ; ^b ; Chung Hyo Kang^a ; ^c ; Heung Kyoung Lee^a ; Raghavendra Achary^a ; ^b ; Ha-Yeon Lee^a ; ^d ; Joo-Youn Lee^e ; Jae Du Ha^a ; Sunjoo Ahn^a ; ^b ; Chi Hoon Park^a ; ^b ; Chong Ock Lee^a ; Jong Yeon Hwang^a ; ^b ; Chang-Soo Yun^a ; ^b ; Hee Jung Jung^a ; ^b ; Sung Yun Cho^a ; ^b ; Hyoung Rae Kim^a ; ^{hyungrk@krict.re.kr} ; Pilho Kim^a ; ^b ; ^{pkim@krict.re.kr}

关键词：Anaplastic lymphoma kinase (ALK) ; Non-small cell lung cancer (NSCLC) ; Ceritinib ; Crizotinib-resistant ; G1202R

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Isolation and characterization of sake yeast mutants with enhanced isoamyl acetate productivity

作者：Toshinari Takahashi ; ^{t-takahasi@kikumasamune.co.jp} ; Yusuke Ohara ; Michiyo Sawatari ; Kazuo Sueno

关键词：Sake yeast ; Isoamyl acetate ; Alcohol acetyl transferase ; ATF1 ; MGA2

刊名：Journal of Bioscience and Bioengineering

出版年：2017

3.Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors

作者：Deepak Bhattarai^a ; ¹ ; Joo Hyun Jung^b ; ¹ ; Seunghyeon Han^a ; Hankyu Lee^b ; Soo Jin Oh^c ; Hyuk Wan Ko^b ; ^{kohw@dongguk.edu} ; Kyeong Lee^a ; ^{Kaylee@dongguk.edu}

关键词：Quinazolinone ; Isoindolinone ; Hedgehog pathway ; Structure hopping ; Smoothened ; Gli

刊名：European Journal of Medicinal Chemistry

出版年：2017

4.Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

作者：Maria De Rosa^a ; ^g ; Lu Lu^b ; ^g ; Edouard Zamaratski^a ; Natalia Szałaj^a ; Sha Cao^c ; Henrik Wadensten^d ; Lena Lenhammar^e ; Johan Gising^a ; Annette K. Roos^f ; Douglas L. Huseby^c ; Rolf Larsson^e ; Per E. André ; n^d ; Diarmaid Hughes^c ; Peter Brandt^a ; Sherry L. Mowbray^b ; ^f ; ^{Sherry.Mowbray@icm.uu.se} ; Anders Karlé ; n^a ; ^{Anders.Karlen@orgfarm.uu.se}

关键词：dabcyl ; 4-((4-(dimethylamino)phenyl)azo)benzoic acid ; DCM ; dichloromethane ; DIEA ; N ; N-diisopropylethylamine ; DMF ; N ; N-dimethylformamide ; E. coli ; Escherichia coli ; EDANS ; 5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid ; EDCI ; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide ; Fmoc ; 9-fluorenylmethoxycarbonyl ; HBTU ; NN ; N&prime ; N&prime ; -tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate ; HATU ; 1-[bis(dimethylamino)methylene]-1H-12 ; 3-triazolo[4 ; 5-b]pyridinium 3-oxide hexafluorophosph

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

5.Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation

作者：Fei Wu^a ; ^b ; Xiangpeng Dai^b ; Wenjian Gan^b ; Lixin Wan^b ; ^c ; Min Li^d ; ^e ; Nicholas Mitsiades^d ; ^e ; Wenyi Wei^b ; Qiang Ding^a ; ^{dr_dingqiang@hotmail.com} ; Jinfang Zhang^b ; ^{jzhang17@bidmc.harvard.edu}

关键词：Cdc20 ; SPOP ; Degradation ; Ubiquitination ; Cancer

刊名：Cancer Letters

出版年：2017

6.Rapid Detection of Rifampicin- and Isoniazid-Resistant Mycobacterium tuberculosis using TaqMan Allelic Discrimination

作者：Davood Darban-Sarokhalil^a ; Mohammad J. Nasiri^b ; Abbas A.I. Fooladi^c ; Parvin Heidarieh^d ; Mohammad M. Feizabadi^e ; ^{mfeizabadi@tums.ac.ir" class="auth_mail" title="E-mail the corresponding author}

关键词：minor groove binder (MGB) ; multidrug-resistant tuberculosis (MDR-TB) ; Mycobacterium tuberculosis ; rapid detection ; TaqMan allelic discrimination

刊名：Osong Public Health and Research Perspectives

出版年：2016

7.Comparative study of enzymatic activities of new KatG mutants from low- and high-level isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

作者：Florence Brossier^a ; ^b ; ^{florence.brossier@psl.aphp.fr" class="auth_mail" title="E-mail the corresponding author} ; Marlè ; ne Boudinet^a ; Vincent Jarlier^a ; ^b ; Sté ; phanie Petrella^c ; ^d ; Wladimir Sougakoff^a ; ^b

关键词：Tuberculosis ; Resistance ; Isoniazid ; Catalase-peroxidase ; KatG ; Enzymatic activities

刊名：Tuberculosis

出版年：2016

8.Overexpression of SOS genes in ciprofloxacin resistant Escherichia coli mutants

作者：Razieh Pourahmad Jaktaji^a ; ^{Razieh_Jaktaji@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Shirin Pasand^b ; ^{pasandshirin@yahoo.com" class="auth_mail" title="E-mail the corresponding author}

关键词：E. coli ; Escherichia coli ; DSB ; double strand break ; NER ; nucleotide excision repairs ; Pol V ; DNA polymerase V ; QRDR ; quinolone resistance determining region ; MIC ; minimum inhibitory concentration ; qRT PCR ; real time PCR ; OD ; optical density

刊名：Gene

出版年：2016

9.Membrane Interactions of the Mason-Pfizer Monkey Virus Matrix Protein and Its Budding Deficient Mutants

关键词：M-PMV ; Mason-Pfizer monkey virus ; MA ; matrix protein ; PI(4 ; 5)P2 ; phosphatidylinositol-4 ; 5-bisphosphate ; PS ; phosphatidylserine ; PCH ; phosphatidylcholine ; diC8-PI(4 ; 5)P2 ; dioctanoyl-PI(4 ; 5)P2 ; WT ; wild type ; NOE ; nuclear Overhauser effect ; NOESY ; NOE spectroscopy ; PDB ; Protein Data Bank ; RDC ; residual dipolar coupling ; HSQC ; heteronuclear single quantum coherence ; CCSD ; combined chemical shift difference ; MST ; microscale thermophoresis ; DRM ; detergent-resistant membrane ; CA ; capsid protein ; Myr-G

刊名：Journal of Molecular Biology

出版年：2016

10.Molecular characterization, fitness and mycotoxin production of Fusarium graminearum laboratory strains resistant to benzimidazoles

作者：A. Sevastos^a ; A. Markoglou^a ; N.E. Labrou^b ; F. Flouri^a ; A. Malandrakis^a ; ^{tasmal@aua.gr" class="auth_mail" title="E-mail the corresponding author}

关键词：Benzimidazoles ; Resistance mutations ; β2-tubulin ; Cold-sensitivity ; Fitness parameters ; Zearalenone

刊名：Pesticide Biochemistry and Physiology

出版年：2016

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