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在“Elsevier电子期刊”中，命中：202条，耗时：小于0.01 秒

在所有数据库中总计命中：423条

1.Shape-based virtual screening, synthesis and evaluation of novel pyrrolone derivatives as antiviral agents against HCV

作者：Marcella Bassetto^a ; ^{bassettom@cardiff.ac.uk} ; Pieter Leyssen^b ; Johan Neyts^b ; Mark M. Yerukhimovich^c ; David N. Frick^c ; Andrea Brancale^a

关键词：Ligand-based virtual screening ; Shape-similarity search ; Novel pyrrolones ; Anti-HCV activity

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase

作者：Marcella Bassetto^a ; ^{bassettom@cardiff.ac.uk} ; Pieter Leyssen^b ; Johan Neyts^b ; Mark M. Yerukhimovich^c ; David N. Frick^c ; Matthew Courtney-Smith^a ; Andrea Brancale^a

关键词：Structure-based virtual screening ; HCV NS3-helicase ; Piperazine derivatives ; Anti-HCV activity ; NS3 helicase inhibitors

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Construction of a subgenomic CV-B3 replicon expressing emerald green fluorescent protein to assess viral replication of a cardiotropic enterovirus strain in cultured human cells

作者：Michel Wehbe^a ; ^b ; Antoine Huguenin^a ; ^c ; Nicolas Leveque^a ; ^c ; ^d ; Bert L. Semler^d ; Monzer Hamze^b ; Laurent Andreoletti^a ; ^c ; Alexis Bouin^a ; ^{alexis.bouin@etudiant.univ-reims.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Coxsackievirus B3 ; EmGFP reporter ; Enterovirus infection ; Viral replication

刊名：Journal of Virological Methods

出版年：2016

4.Assessment of the activity of directly acting antivirals and other products against different genotypes of hepatitis C virus prevalent in resource-poor countries

作者：Hayat Khan^a ; ^b ; Jan Paeshuyse^a ; Sheeba Murad^b ; Johan Neyts^a ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author}

关键词：Hepatitis C virus ; Direct acting antivirals ; Food additives ; Subgenomic replicons

刊名：Antiviral Research

出版年：2016

5.Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication

作者：Nicky Helsen¹ ; ^&dagger ; ; ^{nicky.helsen@med.kuleuven.be" class="auth_mail" title="E-mail the corresponding author} ; Yannick Debing² ; ^&dagger ; ; Jan Paeshuyse² ; Kai Dallmeier² ; Ruben Boon¹ ; Mar Coll³ ; Pau Sancho-Bru³ ; Christel Claes¹ ; Johan Neyts² ; ^&Dagger ; ; Catherine M. Verfaillie¹ ; ^&Dagger ;

关键词：(+)ssRNA ; positive strand RNA ; (&minus ; )ssRNA ; negative strand RNA ; αSMA ; alpha smooth muscle actin ; AAT ; alpha 1-antitrypsin ; AFP ; alpha fetoprotein ; BLBP ; brain lipid-binding protein ; BMP4 ; bone morphogenetic protein 4 ; COL1A1 ; collagen type 1 alpha 1 ; DLX2 ; distal-less homeobox 2 ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; FBS ; fetal bovine serum ; FGF ; fibroblast growth factor ; FISH ; fluorescence in situ hybridization ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; hESC ; human em

刊名：Journal of Hepatology

出版年：2016

6.Computer-aided identification, synthesis and evaluation of substituted thienopyrimidines as novel inhibitors of HCV replication

作者：Marcella Bassetto^a ; ^{bassettom@cardiff.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Pieter Leyssen^b ; Johan Neyts^b ; Mark M. Yerukhimovich^c ; David N. Frick^c ; Andrea Brancale^a

关键词：Structure-based virtual screening ; Substituted thieno-pyrimidines ; Anti-HCV activity

刊名：European Journal of Medicinal Chemistry

出版年：2016

7.Silencing of hepatitis C virus replication by a non-viral vector based on solid lipid nanoparticles containing a shRNA targeted to the internal ribosome entry site (IRES)

关键词：Hepatitis C ; Solid lipid nanoparticles ; RNAi ; shRNA ; Hyaluronic acid ; HCV-IRES

刊名：Colloids and Surfaces B: Biointerfaces

出版年：2016

8.Soraphen A: A broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity

作者：George Koutsoudakis¹ ; ^# ; Iné ; s Romero-Brey² ; ^&dagger ; ; Carola Berger² ; ^&dagger ; ; Gemma Pé ; rez-Vilaró ; ¹ ; Paula Monteiro Perin³ ; ⁴ ; Florian Wolfgang Rudolf Vondran⁴ ; ⁵ ; Markus Kalesse⁶ ; Kirsten Harmrolfs⁷ ; Rolf Mü ; ller⁷ ; Javier P. Martinez⁸ ; Thomas Pietschmann³ ; ⁴ ; Ralf Bartenschlager² ; ⁹ ; Mark Brö ; nstrup⁶ ; Andreas Meyerhans⁸ ; ¹⁰ ; Juana Dí ; ez¹ ; ^{juana.diez@upf.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：HCV ; hepatitis C virus ; HIV ; human immunodeficiency virus ; VLDL ; very low density lipoprotein ; LDL ; low density lipoprotein ; ACC ; acetyl-CoA carboxylase ; SorA ; Soraphen A ; DMVs ; double membrane vesicles ; HCVcc ; cell culture-derived HCV ; TOFA ; 5-(tetradecyloxy)-2-furoic acid ; MOI ; multiplicity of infection ; EC50 ; half maximal effective concentration ; CC50 ; half maximal cytotoxic concentration ; SI ; selectivity index ; 2&prime ; -C-Met ; 2&prime ; -C-methyladenosine ; PHHs ; primary human hepatocytes ; TCID

刊名：Journal of Hepatology

出版年：2015

9.Dengue virus subgenomic RNA induces apoptosis through the Bcl-2-mediated PI3k/Akt signaling pathway

作者：Yi Liu ; Haibin Liu ; Jing Zou ; Bo Zhang ; Zhiming Yuan

关键词：DENV-2 ; Subgenomic RNA ; Cytopathicity ; Apoptosis ; Bcl-2 ; PI3k/Akt pathway

刊名：Virology

出版年：5 January, 2014

10.Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a

作者：Helen Kylefjord ; Axel Danielsson ; Susanne Sedig ; Oscar Belda ; Daniel Wiktelius ; Lotta Vrang ; Paul Targett-Adams

关键词：Hepatitis C virus ; Genotype 3 ; Replicon ; NS5A ; NS5B ; chimera

刊名：Journal of Virological Methods

出版年：January, 2014

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