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在“Elsevier电子期刊”中，命中：67条，耗时：小于0.01 秒

1.Ischemic Preconditioning protects hepatocytes from ischemia-reperfusion injury via TGR5-mediated anti-apoptosis

作者：Lin Zhuang^a ; ^b ; Ye Fan^a ; ^b ; Ling Lu^a ; ^b ; Wenbin Ding^a ; ^b ; Chuangye Ni^a ; ^b ; Xuehao Wang^a ; ^b ; Feng Zhang^a ; ^b ; ^{zhangfeng1958@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jianhua Rao^a ; ^b ; ^{jianhuarao@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：TGR5 ; Ischemic preconditioning ; Ischemia-reperfusion injury ; Hepatocellular apoptosis

刊名：Biochemical and Biophysical Research Communications

出版年：2016

2.Berberine attenuates high glucose-induced fibrosis by activating the G protein-coupled bile acid receptor TGR5 and repressing the S1P2/MAPK signaling pathway in glomerular mesangial cells

作者：Zhiying Yang^a ; ^c ; ¹ ; Jie Li^b ; ¹ ; Fengxiao Xiong^a ; Junying Huang^a ; Cheng Chen^a ; Peiqing Liu^a ; ^c ; Heqing Huang^a ; ^b ; ^c ; ^{huangheq@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：AP-1 ; active protein-1 ; BBR ; berberine ; DN ; diabetic nephropathy ; ERK ; extracellular signal-regulated kinase ; FN ; fibronectin ; GMCs ; glomerular mesangial cells ; ICAM-1 ; intercellular adhesion molecule-1 ; JNK ; c-Jun-NH2-terminal kinase ; MAPK ; mitogen-activated protein kinase ; S1P ; sphingosine 1-phosphate ; S1P2 ; sphingosine 1-phosphate receptor 2 ; Sphk1 ; sphingosine kinase ; TGF-β1 ; transforming growth factor-beta 1 ; TGR5 ; takeda G -protein-coupled receptor 5

刊名：Experimental Cell Research

出版年：2016

3.Naturally-occurring TGR5 agonists modulating glucagon-like peptide-1 biosynthesis and secretion

作者：Laila Jafri^a ; ^d ; ² ; ^{lailashah9@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Samreen Saleem^b ; ^d ; ^{samreen.qau@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Danielle Calderwood^c ; ^{dcalderwood01@qub.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Anna Gillespie^c ; ^{agillespie14@qub.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Bushra Mirza^d ; ¹ ; ^{bushramirza@qau.edu.pk" class="auth_mail" title="E-mail the corresponding author} ; Brian D. Green^c ; ¹ ; ^{b.green@qub.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：GLP-1 ; GIP ; Incretin ; Secretagogue ; TGR5

刊名：Peptides

出版年：2016

4.TGR5 activation suppressed S1P/S1P2 signaling and resisted high glucose-induced fibrosis in glomerular mesangial cells

作者：Zhiying Yang^a ; ^b ; ^c ; Fengxiao Xiong^a ; Yu Wang^a ; Wenyan Gong^a ; Junying Huang^a ; Cheng Chen^a ; Peiqing Liu^a ; ^b ; ^c ; Heqing Huang^a ; ^b ; ^c ; ^{huangheq@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：INT-777 (PubChem CID ; 45483949) ; JTE-013 (PubChem CID ; 10223146)

刊名：Pharmacological Research

出版年：2016

5.TGR5 and Immunometabolism: Insights from Physiology and Pharmacology

作者：Alessia Perino ; Kristina Schoonjans ; ^{kristina.schoonjans@epfl.ch" class="auth_mail" title="E-mail the corresponding author}

关键词：inflammation ; macrophages ; metabolism ; bile acids ; TGR5

刊名：Trends in Pharmacological Sciences

出版年：2015

6.Novel FXR (farnesoid X receptor) modulators: Potential therapies for cholesterol gallstone disease

作者：Donna D. Yu ; Sreenath S. Andrali ; Hongzhi Li ; Min Lin ; Wendong Huang ; Barry M. Forman

关键词：FXR ; farnesoid X receptor ; CDCA ; chenodeoxycholic acid ; UDCA ; ursodeoxycholic acid ; 6EUDCA ; 6-αethyl-ursodeoxycholic acid ; qPCR ; quantitative polymerase chain reaction ; TGR5 ; G-protein-coupled receptor

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

7.The bile acid TUDCA increases glucose-induced insulin secretion via the cAMP/PKA pathway in pancreatic beta cells

作者：Jean Franciesco Vettorazzi^a ; ^d ; Rosane Aparecida Ribeiro^b ; Patricia Cristine Borck^a ; Renato Chaves Souto Branco^a ; Sergi Soriano^c ; Beatriz Merino^d ; Antô ; nio Carlos Boschero^a ; Angel Nadal^d ; Ivan Quesada^d ; ¹ ; Everardo Magalhã ; es Carneiro^a ; ¹ ; ^{emc@unicamp.br" class="auth_mail" title="E-mail the corresponding author}

关键词：6E-CDCA ; 6-Ethyl-chedeoxycholic acid ; ADP ; Adenosine diphosphate ; AKT or PTB ; Protein kinase B ; ATP ; Adenosine triphosphate ; AUC ; Area under curve ; BSA ; Bovine serum albumin ; cAMP ; Cyclic adenosine monophosphate ; CREB ; cAMP response element-binding protein ; DZX ; Diazoxide ; FXR ; Farnesoid X receptor ; GAPDH ; Glyceraldehyde 3-phosphate dehydrogenase ; GLP-1 ; Glucagon-like peptide 1 ; GLUT-2 ; Glucose transporter 2 ; GSIS ; Glucose-stimulated insulin secretion ; H89 ; Protein kinase A inhibitor ; INT-777 ; 6

刊名：Metabolism

出版年：2016

8.Tu1828 GPBAR1(TGR5) Is Highly Expressed in Human Gastric Cancers and Its Activation by Selective or GPBAR1/FXR Dual Ligands Promotes Epithelial Mesenchymal Transition and Tumor Spreading

作者：Claudio D'Amore ; Luigina Graziosi ; Barbara Renga ; Eleonora Distrutti ; Patrizia Ricci ; Mario Rende ; Annibale Donini ; Stefano Fiorucci

刊名：Gastroenterology

出版年：2016

9.14 TGR5 Promote Tumorigenesis of Cholangiocarcinoma by Up-Regulation of Mortalin

作者：Ai-Di Li ; Xiao-Li Xie ; Junji Ma ; Xiaoyu Jiang ; Lei Chen ; Wei Qi ; Qian Ding ; Jing Han ; Yi-chao Yang ; Dong-xuan Zhang ; MIao-miao Wang ; Huiqing Jiang

刊名：Gastroenterology

出版年：2016

10.Sa1657 FXR and/or TGR5 Bile Acid Receptor Agonists Differently Ameliorate Liver Injury and Steatosis After Acute Binge or Prolonged Alcohol Feeding in Mice

作者：Arvin Iracheta-Vellve ; Jan Petrasek ; Aditya Ambade ; Karen Kodys ; Luciano Adorini ; Gyongyi Szabo

刊名：Gastroenterology

出版年：2016

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