搜索页_+Target+evaluation

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在“Elsevier电子期刊”中，命中：15,313条，耗时：0.1289107 秒

在所有数据库中总计命中：154,881条

1.Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents

作者：Roheeth Kumar Pavana^a ; Shruti Choudhary^a ; Anja Bastian^b ; Michael A. Ihnat^c ; Ruoli Bai^d ; Ernest Hamel^d ; Aleem Gangjee^a ; ^{gangjee@duq.edu}

关键词：AA ; antiangiogenic agents ; MTA ; microtubule targeting agents ; VEGFR-2 ; vascular endothelial growth factor receptor-2 ; PDGFR-β ; platelet-derived growth factor receptor-β ; CAM ; chorioallantoic membrane ; CA ; combretastatin A-4 ; Pgp ; P-glycoprotein ; EGFR ; epidermal growth factor receptor ; TBS ; Tris-buffered saline ; HRP ; horseradish peroxidase ; PY ; phosphotyrosine

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.Synthesis, characterization and liver targeting evaluation of self-assembled hyaluronic acid nanoparticles functionalized with glycyrrhetinic acid

作者：Xiaodan Wang ; Xiangqin Gu ; Huimin Wang ; Yujiao Sun ; Haiyang Wu ; Shirui Mao ; ^{maoshirui@syphu.edu.cn}

关键词：Hyaluronic acid ; Glycyrrhetinic acid ; Polymeric nanoparticles ; Liver-targeting

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

3.Threat evaluation of enemy air fighters via neural network-based Markov chain modeling

作者：Hoyeop Lee^a ; Byeong Ju Choi^a ; Chang Ouk Kim^a ; ^{kimco@yonsei.ac.kr} ; Jin Soo Kim^b ; Ji Eun Kim^b

关键词：Threat evaluation ; Target asset prediction ; Markov chain ; Neural network ; Simulation

刊名：Knowledge-Based Systems

出版年：2017

4.Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations

作者：Elvar Ö ; rn Viktorsson^a ; Mari Gabrielsen^b ; Nugalya Kumarachandran^c ; Ingebrigt Sylte^b ; På ; l Rongved^a ; Ove Alexander Hø ; gmoen Å ; strand^a ; ¹ ; ^{o.a.h.astrand@farmasi.uio.no} ; Eili Tranheim Kase^c ; ¹

关键词：Liver X receptors ; Oxysterols ; Steroid synthesis ; Molecular modelling ; Biological evaluation

刊名：Steroids

出版年：2017

5.Synthesis and in vitro evaluation of pH-sensitive magnetic nanocomposites as methotrexate delivery system for targeted cancer therapy

作者：Juan Wu^a ; Aipeng Deng^b ; Wei Jiang^a ; ^{superfine_jw@126.com} ; Renbing Tian^a ; Yewen Shen^a

关键词：Fe3O4 ; LDH ; MTX ; pH-sensitivity ; Controlled release ; Targeted therapy

刊名：Materials Science and Engineering: C

出版年：2017

6.From the Medical Board of the National Psoriasis Foundation: Treatment targets for plaque psoriasis

作者：April W. Armstrong ; MD ; MPH^a ; ^{aprilarmstrong@post.harvard.edu} ; Michael P. Siegel ; PhD^b ; Jerry Bagel ; MD^c ; ^d ; Erin E. Boh ; MD ; PhD^e ; Megan Buell^b ; Kevin D. Cooper ; MD^f ; Kristina Callis Duffin ; MD ; MS^g ; Lawrence F. Eichenfield ; MD^h ; Amit Garg ; MDⁱ ; Joel M. Gelfand ; MD ; MSCE^j ; Alice B. Gottlieb ; MD ; PhD^k ; John Y.M. Koo ; MD^l ; Neil J. Korman ; MD ; PhD^f ; Gerald G. Krueger ; MD^g ; Mark G. Lebwohl ; MD^m ; Craig L. Leonardi ; MDⁿ ; Arthur M. Mandelin ; MD ; PhD^o ; M. Alan Menter ; MD^p ; Joseph F. Merola ; MD ; MMSC^q ; David M. Pariser ; MD^r ; ^s ; Ronald B. Prussick ; MD ; FRCP^t ; Caitriona Ryan ; MD^p ; Kara N. Shah ; MD^u ; Jeffrey M. Weinberg ; MD^m ; MaryJane O.U. Williams ; MD^a ; Jashin J. Wu ; MD^v ; Paul S. Yamauchi ; MD ; PhD^w ; Abby S. Van Voorhees ; MD^r

关键词：biologics ; body surface area ; outcome measures ; Physician Global Assessment ; psoriasis ; systemic therapies ; treat to target ; treatment ; treatment goals

刊名：Journal of the American Academy of Dermatology

出版年：2017

7.Evaluation of both targeted and non-targeted cell wall polysaccharides in transgenic potatoes

作者：Jie-Hong Huang^a ; ^{jiehonghuang0216@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Anne Kortstee^b ; ^{anne.kortstee@outlook.com" class="auth_mail" title="E-mail the corresponding author} ; Dianka C.T. Dees^b ; ^{dianka.dees@wur.nl" class="auth_mail" title="E-mail the corresponding author} ; Luisa M. Trindade^b ; ^{luisa.trindade@wur.nl" class="auth_mail" title="E-mail the corresponding author} ; Richard G.F. Visser^b ; ^{richard.visser@wur.nl" class="auth_mail" title="E-mail the corresponding author} ; Harry Gruppen^a ; ^{harry.gruppen@wur.nl" class="auth_mail" title="E-mail the corresponding author} ; Henk A. Schols^a ; ^{Henk.Schols@wur.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：Pectin biosynthesis ; Plant cell wall ; Galacturonosyltransferase 1 ; Rhamnosyltransferase ; Solanum tuberosum

刊名：Carbohydrate Polymers

出版年：2017

8.Policy indicators for use in impact evaluations of protected area networks

作者：Vera H. Hausner ; ^{vera.hausner@uit.no} ; Sigrid Engen ; Ellen K. Bludd ; Nigel G. Yoccoz

关键词：Impact evaluations ; Protected areas ; Gifi system ; Alpine ; IUCN ; Aichi target ; Management effectiveness ; PADDD ; Norway ; British Columbia

刊名：Ecological Indicators

出版年：2017

9.“Gold nanoparticles composite-folic acid conjugated graphene oxide nanohybrids” for targeted chemo-thermal cancer ablation: In vitro screening and in vivo studies

作者：Gaurav Chauhan^a ; Vianni Chopra^b ; ^c ; Amit Tyagi^c ; Goutam Rath^a ; Rakesh K Sharma^c ; Amit K. Goyal ; Dr.^a ; ^{amitkumargoyal1979@gmail.com} (Professor Head)

关键词：Graphene oxide ; Gold nanoparticles ; targeted chemotherapy ; Near-infrared (NIR) sensitivity ; Photo-thermal tumor ablation

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

10.Screening and identification of molecular targets for cancer therapy

作者：Alshaimaa Abdelmoez^a ; ^b ; Dé ; bora C. Coraç ; a-Huber^c ; Gudrun C. Thurner^b ; Paul Debbage^b ; Peter Lukas^a ; Sergej Skvortsov^a ; Ira-Ida Skvortsova^a ; ^{ira.skvortsova@i-med.ac.at}

关键词：Cancer ; Cellular membranes ; Proteomics ; Target ; Signaling pathways ; Cancer stem cells

刊名：Cancer Letters

出版年：2017

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