搜索页_+Tubulin-binding

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在“Elsevier电子期刊”中，命中：958条，耗时：0.0259893 秒

在所有数据库中总计命中：4,037条

1.Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation

作者：Raghuram Ambadipudi ; Elias Georges ; ^{elias.georges@mcgill.ca}

关键词：MRP1 ; ABCC1 ; Protein interactions ; Tubulin ; Linker 1 domain ; Phosphorylation

刊名：Biochemical and Biophysical Research Communications

出版年：2017

2.Structural Basis of cis- and trans-Combretastatin Binding to Tubulin

作者：Roberto Gaspari¹ ; ⁴ ; Andrea E. Prota² ; ⁴ ; Katja Bargsten² ; Andrea Cavalli¹ ; ³ ; ^{andrea.cavalli@iit.it} ; Michel O. Steinmetz² ; ⁵ ; ^{michel.steinmetz@psi.ch}

关键词：microtubule-targeting agents ; tubulin ; protein-ligand interaction ; cis-trans isomerism ; switchable molecules ; X-ray crystallography ; metadynamics

刊名：Chem

出版年：2017

3.Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers

作者：A.V. Subba Rao^a ; ^b ; Konderu Swapna^c ; Siddiq Pasha Shaik^a ; ^b ; V. Lakshma Nayak^a ; T. Srinivasa Reddy^c ; Satish Sunkari^a ; ^b ; Thokhir Basha Shaik^a ; Chandrakant Bagul^c ; Ahmed Kamal^a ; ^b ; ^c ;

关键词：Combretastatin A-4 ; Benzothiazole ; Triazoles and tetrazoles ; Antiproliferative activity ; Tubulin polymerization ; Colchicine competition assay ; Apoptosis

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors

作者：Ilhem Khelifi^a ; Timothé ; e Naret^a ; Dolor Renko^a ; Abdallah Hamze^a ; Guillaume Bernadat^a ; Jé ; rome Bignon^b ; Christine Lenoir^b ; Joë ; lle Dubois^b ; Jean-Daniel Brion^a ; Olivier Provot^a ; ^{olivier.provot@u-psud.fr} ; Mouad Alami^a ; ^{mouad.alami@u-psud.fr}

关键词：Cancer ; Quinoline ; isoCA-4 ; Cytotoxicity ; Tubulin ; Binding

刊名：European Journal of Medicinal Chemistry

出版年：2017

5.The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase

作者：Caezar Al-Jassar¹ ; ² ; Antonina Andreeva¹ ; ² ; Deepak D. Barnabas¹ ; Stephen H. McLaughlin¹ ; Christopher M. Johnson¹ ; Minmin Yu¹ ; Mark van Breugel¹ ; ³ ; ^{vanbreug@mrc-lmb.cam.ac.uk}

关键词：Cep104 ; TOG ; tubulin ; zinc finger ; Nek1 ; CP110 ; centriole ; basal body ; cilia

刊名：Structure

出版年：2017

6.Understanding the Binding of cis and trans Isomers of Combretastatin to Tubulin

作者：Isabel Rozas¹ ; ^{rozasi@tcd.ie}

刊名：Chem

出版年：2017

7.Synthesis and cytostatic properties of polyfunctionalized furanoallocolchicinoids

作者：Iuliia A. Gracheva^a ; Iuliia V. Voitovich^a ; Vladimir I. Faerman^a ; Nikolay S. Sitnikov^a ; Ekaterina V. Myrsikova^b ; Hans-Gunther Schmalz^c ; ^{schmalz@uni-koeln.de} ; Elena V. Svirshevskaya^b ; ^d ; ^{esvir@yandex.ru} ; Alexey Yu Fedorov^a ; ^{afnn@rambler.ru}

关键词：Colchicine ; Allocolchicinoids ; Cross-coupling ; Antitumor activity ; Tubulin binding agents

刊名：European Journal of Medicinal Chemistry

出版年：2017

8.JAK family members: Molecular cloning, expression profiles and their roles in leptin influencing lipid metabolism in Synechogobius hasta

作者：Kun Wu^a ; Xiao-Ying Tan^a ; ^b ; ^{txy7933@163.com} ; ^{txy7933@mail.hzau.edu.cn} ; Yi-Huan Xu^a ; Xi Shi^a ; Yao-Fang Fan^a ; Dan-Dan Li^a ; Xu Liu^c

关键词：ACC ; acetyl-CoA carboxylase ; ATGL ; adipose triglyceride lipase ; FAS ; fatty acid synthase ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; HPRT ; hypoxanthine-guanine phosphoribosyl transferase ; HSL ; hormone-sensitive lipase ; JAK ; janus kinase ; LepR ; leptin receptor ; ME ; malic enzyme ; MS-222 ; tricaine methanesulfonate ; RPL7 ; ribosomal protein L7 ; STAT ; signal transducer and activator of transcription ; TBP ; TATA-box-binding protein ; TG ; triglyceride ; TUBA ; tubulin alpha chain ; UBCE ; ubiquitin-conj

刊名：Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

出版年：2017

9.Characterization of the γ-aminobutyric acid signaling system in the zebrafish (Danio rerio Hamilton) central nervous system by reverse transcription-quantitative polymerase chain reaction

作者：Arianna Cocco ^{arianna.cocco@neuro.uu.se} ; A.M. Carolina Rö ; nnberg ^{carrr0-@hotmail.com} ; Zhe Jin ^{zhe.jin@neuro.uu.se} ; Gonç ; alo Igreja André ; ¹ ; ^{goncalo.igrejaandre@research.uwa.edu.au} ; Laura E. Vossen ^{laura.vossen@neuro.uu.se} ; Amol K. Bhandage ^{amol.bhandage@neuro.uu.se} ; Per-Ove Thö ; rnqvist ^{per-ove.thornqvist@neuro.uu.se} ; Bryndis Birnir ^{bryndis.birnir@neuro.uu.se} ; Svante Winberg ; ^{svante.winberg@neuro.uu.se}

关键词：abat ; 4-aminobutyrate aminotransferase ; actb1 ; actin β1 ; CCCs ; chloride-cation co-transporters ; EDTA ; ethylenediaminetetraacetic acid ; GABA ; γ-aminobutyric acid ; GABA-T ; GABA-α-ketoglutarate transaminase ; GAD ; glutamate decarboxylase ; RT-qPCR ; reverse transcription&ndash ; quantitative polymerase chain reaction ; SLC6 ; solute carrier 6 ; TAE ; Tris&ndash ; Acetate&ndash ; EDTA ; TBE ; Tris&ndash ; Borate&ndash ; EDTA ; tbp ; TATA-box binding protein ; tuba1b ; tubulin α1b

刊名：Neuroscience

出版年：2017

10.Novel drug design for Chagas disease via targeting Trypanosoma cruzi tubulin: Homology modeling and binding pocket prediction on Trypanosoma cruzi tubulin polymerization inhibition by naphthoquinone derivatives

作者：Charles O. Ogindo^a ; Mozna H. Khraiwesh^b ; Matthew George Jr.^c ; Yakini Brandy^a ; Nailah Brandy^a ; Ayele Gugssa^b ; Mohammad Ashraf^d ; Muneer Abbas^e ; ^f ; William M. Southerland^c ; Clarence M. Lee^b ; Oladapo Bakare^a ; Yayin Fang^c ;

关键词：Chagas disease ; Trypanosoma cruzi ; Naphthoquinone derivatives ; Tubulin polymerization inhibition ; Homology modeling ; Binding site prediction ; Structure based drug design (SBDD)

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

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