搜索页_+Tumor-Vascular-Disrupting-Agent

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在“Elsevier电子期刊”中，命中：58条，耗时：0.0569717 秒

在所有数据库中总计命中：684条

1.Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents

作者：Laxman Devkota^a ; ^&dagger ; ; Chen-Ming Lin^a ; ^&dagger ; ; Tracy E. Strecker^a ; Yifan Wang^a ; Justin K. Tidmore^a ; Zhi Chen^a ; Rajsekhar Guddneppanavar^a ; Christopher J. Jelinek^a ; Ramona Lopez^b ; Li Liu^b ; Ernest Hamel^c ; Ralph P. Mason^b ; David J. Chaplin^a ; ^d ; Mary Lynn Trawick^a ; ^{Mery_Lynn_Trawick@baylor.edu" class="auth_mail" title="E-mail the corresponding author} ; Kevin G. Pinney^a ; ^{Kevin_Pinney@baylor.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Small-molecule synthesis ; Inhibitors of tubulin polymerization ; Vascular disrupting agents ; Amino acid prodrug salts ; Anti-cancer agents ; Combretastatin analogs ; Benzosuberene analogs ; Dihydronaphthalene analogs

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

2.TNF alpha signaling is associated with therapeutic responsiveness to vascular disrupting agents in endocrine tumors

作者：Constanze Hantel^a ; ^{Constanze.Hantel@med.uni-muenchen.de" class="auth_mail" title="E-mail the corresponding author} ; Alexandra Ozimek^b ; Regia Lira^c ; Bruno Ragazzon^d ; Carsten Jä ; ckel^e ; Roman Frantsev^a ; Martin Reincke^a ; Jé ; rô ; me Bertherat^d ; Thomas Mussack^b ; Felix Beuschlein^a

关键词：Endocrine tumors ; Tumor-Vascular-Disrupting-Agent ; TNFα ; TNFAIP3/A20

刊名：Molecular and Cellular Endocrinology

出版年：2016

3.CA-1H, a novel oxazole bearing analogue of combretastatin A-4, disrupts the tumor vasculatures and inhibits the tumor growth via inhibiting tubulin polymerization

作者：Fuguo Han^a ; Peng Wang^a ; Wei Zhang^b ; Jing Li^a ; Qun Zhang^c ; Xin Qi^a ; ^{qxhin@163.com" class="auth_mail" title="E-mail the corresponding author} ; Ming Liu^a ; ^{lmouc@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Tumor ; Vascular disrupting agents ; Combretastatin A-4 ; Oxazole

刊名：Biomedicine & Pharmacotherapy

出版年：2016

4.Vascular disrupting activity of combretastatin analogues

作者：Elena Porcù ; ^a ; ¹ ; Alessia Salvador^b ; ¹ ; Irina Primac^b ; Stefania Mitola^c ; Roberto Ronca^c ; Cosetta Ravelli^c ; Roberta Bortolozzi^a ; Daniela Vedaldi^b ; Romeo Romagnoli^d ; Giuseppe Basso^a ; Giampietro Viola^a ; ^{giampietro.viola.1@unipd.it" class="auth_mail" title="E-mail the corresponding author}

关键词：Vascular disrupting agents ; Angiogenesis ; Combretastatin ; Tubulin binding agents ; HUVEC

刊名：Vascular Pharmacology

出版年：2016

5.Tunable release of chemotherapeutic and vascular disrupting agents from injectable fiber fragments potentiates combination chemotherapy

作者：Xiaoming Luo^a ; ^b ; ¹ ; Guisen Xu^c ; ¹ ; Jiaojun Wei^a ; Maohua Chen^a ; Hong Zhang^a ; Xiaohong Li^a ; ^{xhli@swjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; ^{xiaohongli@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Injectable fiber fragment ; Release duration ; Blood vessel disruption ; Antitumor efficacy ; Metastasis inhibition

刊名：International Journal of Pharmaceutics

出版年：2016

6.Combretastatin A-4 derived 5-(1-methyl-4-phenyl-imidazol-5-yl)indoles with superior cytotoxic and anti-vascular effects on chemoresistant cancer cells and tumors

作者：Katharina Mahal^a ; Bernhard Biersack^a ; Sebastian Schruefer^a ; Marcus Resch^b ; Ralf Ficner^b ; Rainer Schobert^a ; ^{rainer.schobert@uni-bayreuth.de" class="auth_mail" title="E-mail the corresponding author} ; Thomas Mueller^c

关键词：Imidazole ; Indole ; Anticancer drugs ; Combretastatin A-4 ; Vascular-disrupting agents ; Mouse tumor xenografts

刊名：European Journal of Medicinal Chemistry

出版年：2016

7.Pharmacokinetic strategies to improve drug penetration and entrapment within solid tumors

作者：Ahmed M. Al-Abd^a ; ^b ; ^c ; Zekra K. Aljehani^c ; Rana W. Gazzaz^c ; Sarah H. Fakhri^c ; Aisha H. Jabbad^c ; Abdulrahman M. Alahdal^c ; Vladimir P. Torchilin^b ; ^d ; ^{v.torchilin@neu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ECM ; extracellular matrix ; IFP ; interstitial fluid pressure ; EPR ; enhanced permeation and retention ; AI ; angiogenesis inhibitors ; VEGF ; vascular endothelial growth factor ; VDA ; vascular disrupting agent ; CEP ; circulating endothelial progenitor ; TACE ; transarterial chemoembolization ; P-gp ; permeability glycoprotein ; MDR ; multidrug resistance protein

刊名：Journal of Controlled Release

出版年：2015

8.Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization

作者：Christine A. Herdman^a ; Laxman Devkota^a ; Chen-Ming Lin^a ; Haichan Niu^a ; Tracy E. Strecker^a ; Ramona Lopez^b ; Li Liu^b ; Clinton S. George^a ; Rajendra P. Tanpure^a ; Ernest Hamel^c ; David J. Chaplin^a ; ^d ; Ralph P. Mason^b ; Mary Lynn Trawick^a ; Kevin G. Pinney^a ; ^{Kevin_Pinney@baylor.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Inhibitors of tubulin polymerization ; Benzosuberene analogues ; Vascular disrupting agents ; Small-molecule synthesis

刊名：Bioorganic & Medicinal Chemistry

出版年：2015

9.The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts

作者：Tracy E. Strecker^a ; ¹ ; Samuel O. Odutola^b ; ¹ ; Ramona Lopez^c ; Morgan S. Cooper^a ; Justin K. Tidmore^a ; Amanda K. Charlton-Sevcik^a ; Li Li^c ; Matthew T. MacDonough^a ; Mallinath B. Hadimani^a ; Anjan Ghatak^a ; ^&dagger ; ; Li Liu^c ; David J. Chaplin^d ; Ralph P. Mason^c ; Kevin G. Pinney^a ; ^b ; Mary Lynn Trawick^a ; ^b ; ^{mary_lynn_trawick@baylor.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ANOVA ; analysis of variance ; BLI ; bioluminescence imaging ; CA4 ; combretastatin A-4 ; CA4P ; combretastatin A-4 phosphate ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; DMSO ; dimethyl sulfoxide ; DTT ; dithiothreitol ; FAK ; focal adhesion kinase ; FDA ; Federal Drug Administration ; FITC ; fluorescein isothiocyanate ; GI50 ; median growth inhibitory concentration ; HRP ; horseradish peroxidase ; HUVEC ; human umbilical vein endothelial cells ; MLC ; myosin light chain ; NMII ; non-muscle myosin II ; OXi8006 ; 2-(3&prime

刊名：Cancer Letters

出版年：2015

10.Introduction to Irreversible Electroporation鈥?/span>Principles and Techniques

作者：Kenneth R. Thomson ; MD ; FRANZCR ; EBIR ; ^{k.thomson@alfred.org.au" class="auth_mail" title="E-mail the corresponding author} ; Helen Kavnoudias ; PhD ; Robert E. Neal II ; PhD

关键词：electroporation ; ablation ; tumor

刊名：Techniques in Vascular and Interventional Radiology

出版年：2015

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