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在“Elsevier电子期刊”中，命中：27条，耗时：0.0839607 秒

在所有数据库中总计命中：11条

1.Efficacy, safety, and pharmacokinetics of natalizumab in Japanese multiple sclerosis patients: A double-blind, randomized controlled trial and open-label pharmacokinetic study

作者：Takahiko Saida^a ; ^{saida_takahiko@maia.eonet.ne.jp} ; Jun-ichi Kira^b ; Shuji Kishida^c ; Takashi Yamamura^d ; Yukiko Sudo^e ; Kazutaka Ogiwara^e ; JT Tibung^e ; Nisha Lucas^f ; Meena Subramanyam^f ; On behalf of Natalizumab Trial Principal Investigators

关键词：AE ; adverse event ; ARR ; annualized relapse rate ; AUC ; area under the concentration time curve ; AUC0&ndash ; last ; area under the curve to the last measurable concentration of a dosing interval ; AUC0&ndash ; &infin ; area under the curve to infinity ; AUC0&ndash ; 672 ; area under the curve for dosing interval ; CI ; confidence interval ; CL ; systemic clearance ; Cmax ; maximum concentration ; Ctrough ; trough concentration ; EDSS ; Expanded Disability Status Scale ; ELISA ; enzyme-linked immunosorbent assay ; Gd ; g

刊名：Multiple Sclerosis and Related Disorders

出版年：2017

2.Impact of daclizumab versus interferon beta-1a on patient-reported outcomes in relapsing-remitting multiple sclerosis

作者：Ying Liu^a ; ^{ying.liu@biogen.com} ; Timothy Vollmer^b ; ^{timothy.vollmer@ucdenver.edu} ; Eva Havrdova^c ; ^{Eva.Havrdova@lf1.cuni.cz} ; Katherine Riester^a ; ^{katherine.riester@biogen.com} ; Andrew Lee^a ; ^{andrew.lee@biogen.com} ; Glenn Phillips^a ; ^{glenn.phillips@biogen.com} ; Ping Wang^a ; ^{ping.wang@biogen.com} ; Guido Sabatella^a ; ^{guido.sabatella@biogen.com}

关键词：ARR ; annualized relapse rate ; BDI-II ; Beck Depression Inventory-II ; EQ-5D ; Euro-Qol 5-Dimensions ; IFN ; interferon ; IM ; intramuscular ; MRI ; magnetic resonance imaging ; MS ; multiple sclerosis ; MSIS-29 ; 29-item Multiple Sclerosis Impact Scale ; OR ; odds ratio ; PHYS ; physical impact subscale ; PRO ; patient-reported outcome ; PSYCH ; psychological impact subscale ; QoL ; quality of life ; RRMS ; relapsing-remitting multiple sclerosis ; SC ; subcutaneous ; VAS ; visual analog scale

刊名：Multiple Sclerosis and Related Disorders

出版年：2017

3.Vitamin D supplementation reduces relapse rate in relapsing-remitting multiple sclerosis patients treated with natalizumab

作者：Julie Hejgaard Laursen ; ^{juliehejgaard@hotmail.com} ; Helle Bach Sø ; ndergaard ; Per Soelberg Sø ; rensen ; Finn Sellebjerg ; Annette Bang Oturai

关键词：Multiple sclerosis ; 25-hydroxyvitamin D ; Vitamin D3 supplement ; Annualized relapse-rate ; Immunomodulation

刊名：Multiple Sclerosis and Related Disorders

出版年：2016

4.Multiple sclerosis relapses are associated with increased fatigue and reduced health-related quality of life - A post hoc analysis of the TEMSO and TOWER studies

关键词：ARR ; annualized relapse rate ; EDSS ; Expanded Disability Status Scale ; FIS ; fatigue impact scale ; FS ; functional system ; HRQoL ; health-related quality of life ; MCS ; (short form 36) mental health component summary ; MID ; minimally important difference ; PCS ; (short form 36) physical health component summary ; QoL ; quality of life ; SF-6D ; short form 6-dimension ; SF-36 ; short form 36

刊名：Multiple Sclerosis and Related Disorders

出版年：2016

5.Relapse rates in patients with multiple sclerosis treated with fingolimod: Subgroup analyses of pooled data from three phase 3 trials

作者：Tobias Derfuss^a ; ^{Tobias.Derfuss@usb.ch" class="auth_mail" title="E-mail the corresponding author} ; Daniel Ontaneda^b ; Jacqueline Nicholas^c ; Xiangyi Meng^d ; Kathleen Hawker^d ; ¹

关键词：Clinical efficacy ; Early treatment ; Disability

刊名：Multiple Sclerosis and Related Disorders

出版年：2016

6.Comparing outcomes from clinical studies of oral disease-modifying therapies (dimethyl fumarate, fingolimod, and teriflunomide) in relapsing MS: Assessing absolute differences using a number needed to treat analysis

作者：Mark S. Freedman^a ; ^{mfreedman@toh.ca} ; Xavier Montalban^b ; Aaron E. Miller^c ; Catherine Dive-Pouletty^d ; Steven Hass^e ; Karthinathan Thangavelu^e ; Thomas P. Leist^f

关键词：AE ; adverse event ; ARR ; annualized relapse rate ; DMF ; dimethyl fumarate ; DMT ; disease-modifying therapy ; EDSS ; Expanded Disability Status Scale ; FS ; Functional System ; IV ; intravenous ; MS ; multiple sclerosis ; NNH ; number needed to harm ; NNT ; number needed to treat

刊名：Multiple Sclerosis and Related Disorders

出版年：2016

7.Subcutaneous interferon β-1a in pediatric patients with multiple sclerosis: Regional differences in clinical features, disease management, and treatment outcomes in an international retrospective study

作者：Lauren B. Krupp^a ; ^{lauren.krupp@nyumc.org" class="auth_mail" title="E-mail the corresponding author} ; Daniela Pohl^b ; Angelo Ghezzi^c ; Alexey Boyko^d ; Silvia Tenembaum^e ; Liang Chen^f ; Ernesto Aycardi^f ; ¹ ; Brenda Banwell^g ; on behalf of the REPLAY Study Group

关键词：ARR ; annualized relapse rate ; BMI ; body mass index ; DMD ; disease-modifying therapy ; DMT ; disease-modifying therapy ; IFN ; interferon ; ME ; medical events ; MS ; multiple sclerosis ; ROW ; rest of the world ; SD ; standard deviation ; US ; United States

刊名：Journal of the Neurological Sciences

出版年：2016

8.Comparison of efficacy and tolerability of azathioprine, mycophenolate mofetil, and cyclophosphamide among patients with neuromyelitis optica spectrum disorder: A prospective cohort study

作者：Yan Xu^a ; ¹ ; Qian Wang^b ; ¹ ; Hai-tao Ren^a ; Lin Qiao^b ; Yao Zhang^a ; Yun-Yun Fei^b ; Yan Zhao^b ; Li-ying Cui^c ; ^d ; ^{pumchcuily@sina.com" class="auth_mail" title="E-mail the corresponding author}

关键词：NMO ; neuromyelitis optica ; CNS ; central nervous system ; AQP4-IgG ; autoantibodies to aquaporin-4 ; NMOSD ; NMO spectrum disorder ; SLE ; systemic lupus erythematosus ; SS ; Sjö ; qren's syndrome ; AZA ; azathioprine ; MMF ; mycophenolate mofetil ; CTX ; cyclophosphamide ; EDSS ; Expanded Disability Status Scale ; ARR ; annualized relapse rate ; KM ; Kaplan-Meier

刊名：Journal of the Neurological Sciences

出版年：2016

9.Increased resistin levels in the serum and cerebrospinal fluid of patients with neuromyelitis optica

作者：Yuan Qi^a ; Kun Jia^a ; Da-Qi Zhang^a ; Ting Li^a ; Li-Min Li^a ; Lin-Jie Zhang^a ; Jing Wang^a ; Chun-Li Gao^a ; Li-Sha Sun^c ; Fu-Dong Shi^a ; ^b ; Li Yang^a ; ^{yangli2001@tmu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; ^{yungli2001@yahoo.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Resistin ; Neuromyelitis optica ; Inflammation ; Annualized relapse rate ; hs-CRP

刊名：Clinica Chimica Acta

出版年：2016

10.Long-term efficacy and safety of intramuscular interferon beta-1a: Randomized postmarketing trial of two dosing regimens in Japanese patients with relapsing-remitting multiple sclerosis

作者：Takahiko Saida^a ; ^{Saida_takahiko@maia.eonet.ne.jp" class="auth_mail" title="E-mail the corresponding author} ; Jun-ichi Kira^b ; ^{kira@neuro.med.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Yasuhiro Ueno^c ; ^{yasuhiro.ueno@biogen.com" class="auth_mail" title="E-mail the corresponding author} ; Naozumi Harada^c ; ^{nysharad@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Toshiyuki Hirakata^c ; ^{toshiyuki.hirakata@biogen.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ARR ; annualized relapse rate ; CI ; confidence interval ; EDSS ; Expanded Disability Status Scores ; Gd+ ; gadolinium-enhancing ; IFN beta ; interferon beta ; IFN beta-1a ; interferon beta-1a ; IM ; intramuscular ; MedDRA ; Medical Dictionary for Regulatory Activities ; MRI ; magnetic resonance imaging ; MS ; multiple sclerosis ; MSCRG ; Multiple Sclerosis Collaborative Research Group ; RRMS ; relapsing remitting multiple sclerosis ; SD ; standard deviation

刊名：Multiple Sclerosis and Related Disorders

出版年：2016

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