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在“Elsevier电子期刊”中，命中：118条，耗时：0.0719686 秒

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1.Gut microbiome and liver disease

作者：Naga S. Betrapally^a ; Patrick M. Gillevet^a ; Jasmohan S. Bajaj^b ; ^{jasmohan.bajaj@vcuhealth.org}

关键词：NAFLD ; nonalcoholic fatty liver disease ; ALD ; alcoholic liver disease ; TLRs ; Toll-like receptors ; NLRs ; Nod-like receptors ; NASH ; nonalcoholic steatohepatitis ; BT ; bacterial translocation ; HE ; hepatic encephalopathy ; ACLF ; acute on chronic liver failure ; TNF-α ; tumor necrosis factor alpha ; RELMβ ; resistin-like molecule β ; MCD ; methionine-choline deficient ; NCD ; normal chow diet ; LPS ; lipopolysaccharide ; IM ; intestinal microbiota ; SCFA ; short chain fatty acids ; LCFA ; long chain fatty acids ; sAH

刊名：Translational Research

出版年：2017

2.A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer

作者：Amon Asgharpour¹ ; ^&dagger ; ; Sophie C. Cazanave¹ ; ^&dagger ; ; ^{sophie.cazanave@vcuhealth.org" class="auth_mail" title="E-mail the corresponding author} ; Tommy Pacana¹ ; Mulugeta Seneshaw¹ ; Robert Vincent¹ ; Bubu A. Banini¹ ; Divya Prasanna Kumar¹ ; Kalyani Daita¹ ; Hae-Ki Min¹ ; Faridoddin Mirshahi¹ ; Pierre Bedossa² ; Xiaochen Sun³ ; Yujin Hoshida³ ; Srinivas V. Koduru⁴ ; Daniel Contaifer Jr.⁵ ; Urszula Osinska Warncke⁵ ; ⁶ ; Dayanjan S. Wijesinghe⁵ ; ⁶ ; Arun J. Sanyal¹ ; ^{arun.sanyal@vcuhealth.org" class="auth_mail" title="E-mail the corresponding author}

关键词：ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; B6 ; C57BL/6J ; CD ; chow diet ; CK-18 ; cytokeratin-18 ; DIAMOND ; diet-induced animal model of non-alcoholic fatty liver disease ; ER ; endoplasmic reticulum ; FDR ; false discovery rate ; GTT ; glucose tolerance test ; IRE-1 ; inositol-requiring enzyme-1 ; ITT ; insulin tolerance test ; JNK ; c-Jun NH2-terminal kinase ; LDL-c ; low-density lipoprotein-cholesterol ; MCD ; methionine choline deficient ; NAFLD ; non-alcoholic fatty liver disease ; NASH ; non-

刊名：Journal of Hepatology

出版年：2016

3.Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design

作者：Scott Friedman^a ; ^{scott.friedman@mssm.edu" class="auth_mail" title="E-mail the corresponding author} ; Arun Sanyal^b ; Zachary Goodman^c ; Eric Lefebvre^d ; Mildred Gottwald^d ; Laurent Fischer^d ; Vlad Ratziu^e

关键词：Cenicriviroc ; Non-alcoholic steatohepatitis ; Non-alcoholic fatty liver ; Liver fibrosis ; Metabolic syndrome ; Type 2 diabetes mellitus

刊名：Contemporary Clinical Trials

出版年：2016

4.(S)YS-51, a novel isoquinoline alkaloid, attenuates obesity-associated non-alcoholic fatty liver disease in mice by suppressing lipogenesis, inflammation and coagulation

作者：Eun Jung Park^a ; ^b ; Young Min Kim^a ; Hye Jung Kim^a ; ^b ; Se-Yun Jang^c ; Moo Hyun Oh^c ; Duck-Hyung Lee^c ; ^{dhlee@sogang.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Ki Churl Chang^a ; ^b ; ^{kcchang@gnu.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：(S)YS-51 ; (S)6 ; 7-dihydroxy-1-(β-naphthylmethyl)-123 ; 4-tetrahydroisoquinoline ; ALT ; alanine aminotransferase ; CD36 ; cluster of differentiation 36 ; GTT ; glucose tolerance test ; HMGB1 ; high mobility group box 1 ; ICAM-1 ; intercellular cell adhesion molecule-1 ; IR ; insulin resistance ; ITT ; insulin tolerance test ; LDH ; lactate dehydrogenase ; LKB1 ; liver kinase B1 ; MCP-1 ; monocyte chemotactic protein-1 ; NAFLD ; nonalcoholic fatty liver disease ; NASH ; nonalcoholic steatohepatitis ; PAI-1 ; plasminogen ac

刊名：European Journal of Pharmacology

出版年：2016

5.Betaine chemistry, roles, and potential use in liver disease

作者：Christopher R. Day^a ; Stephen A. Kempson^b ; ^{skempson@iupui.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ALD ; alcoholic liver disease ; AMPK ; AMP-activated protein kinase ; BGT1 ; Na+/Cl&minus ; -dependent betaine&ndash ; GABA transporter ; BHMT ; betaine&ndash ; homocysteine methyltransferase ; DMG ; dimethylglycine ; NAFLD ; non-alcoholic fatty liver disease ; NASH ; non-alcoholic steatohepatitis ; OCTN2 ; organic cation/carnitine transporter ; SAH ; S-adenosylhomocysteine ; SAM ; S-adenosylmethionine ; SIT1 ; Na+-dependent imino acid transporter ; SNAT ; Na+-dependent neutral amino acid transporter

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2016

6.Chronic fructose intake accelerates non-alcoholic fatty liver disease in the presence of essential hypertension

作者：Layla Mendonç ; a Lí ; rio^a ; Ludimila Forechi^a ; Tadeu Caliman Zanardo^b ; Hiago Martins Batista^c ; Eduardo Frizera Meira^a ; ^c ; Breno Valentim Nogueira^b ; José ; Geraldo Mill^a ; Marcelo Perim Baldo^a ; ^{marcelobaldo@ymail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Fructose ; Metabolic disorder ; Visceral fat ; Hypertension ; Fat liver disease

刊名：Journal of Diabetes and its Complications

出版年：2016

7.Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models

作者：Bernd Schnabl^a ; Salman Farshchi-Heydari^b ; Rohit Loomba^a ; Robert F. Mattrey^b ; ^c ; ^d ; Carl K. Hoh^b ; ^c ; ^d ; Claude B. Sirlin^b ; ^c ; ^d ; David A. Brenner^a ; Cynthia A. Behling^e ; David R. Vera^b ; ^c ; ^d ; ^f ; ^{dvera@ucsd.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CDAA ; choline-deficient L-amino acid-defined ; CSAA ; choline-supplemented L-amino acid-defined ; DEN ; N-diethylnitrosamine ; FPF ; false-positive fraction ; GSA ; Galactosyl human serum albumin ; NAFLD ; non-alcoholic fatty liver disease ; NASH ; non-alcoholic steatohepatitis ; PET ; positron-emission tomography ; TAC ; time&ndash ; activity curve ; TPF ; true-positive fraction

刊名：Nuclear Medicine and Biology

出版年：2016

8.CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy

作者：Xiang Zhang¹ ; Juqiang Han¹ ; ² ; Kwan Man³ ; Xiaoxing Li¹ ; ⁴ ; Jinghua Du¹ ; ⁵ ; Eagle S.H. Chu¹ ; Minnie Y.Y. Go¹ ; Joseph J.Y. Sung¹ ; Jun Yu¹ ; ^{junyu@cuhk.edu.hk" class="auth_mail" title="E-mail the corresponding author}

关键词：CXCR3 ; CXC chemokine receptor 3 ; NASH ; non-alcoholic steatohepatitis ; NAFLD ; non-alcoholic fatty liver disease ; CXCR3&minus ; /&minus ; CXCR3 knockout ; WT ; wild-type ; MCD ; methionine-and-choline-deficient ; HFHC ; high-fat high-carbohydrate high-cholesterol ; ER ; endoplasmic reticulum ; TNF-α ; tumor necrosis factor alpha ; MCP-1 ; monocyte chemoattractant protein 1 ; IL ; interleukin ; ICAM-1 ; intercellular adhesion molecule-1 ; LXR ; liver X receptors ; SREBP-1c ; sterol regulatory element binding protein iso

刊名：Journal of Hepatology

出版年：2016

9.Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease

作者：Kristine Griffett ; Thomas P. Burris ; ^{burristp@slu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Nuclear receptor ; LXR ; Transcription ; NASH ; Lipogenesis ; Drug discovery

刊名：Biochemical and Biophysical Research Communications

出版年：2016

10.Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency

作者：Benjamin L. Farah¹ ; Dustin J. Landau² ; Rohit A. Sinha¹ ; Elizabeth D. Brooks² ; ³ ; Yajun Wu⁴ ; Suet Yin Sarah Fung⁵ ; Tomohiro Tanaka⁶ ; Masahiro Hirayama⁶ ; Boon-Huat Bay⁴ ; Dwight D. Koeberl² ; ⁷ ; ^{dwight.koeberl@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Paul M. Yen¹ ; ⁸ ; ^{paul.yen@duke-nus.edu.sg" class="auth_mail" title="E-mail the corresponding author}

关键词：G6Pase α ; glucose-6-phosphatase α ; G6PC ; glucose-6-phosphatase α catalytic subunit ; GSDIa ; glycogen storage disease type Ia ; G6P ; glucose-6-phosphate ; mTOR ; mammalian target of rapamycin ; AMPK ; 5&rsquo ; AMP-activated protein kinase ; ULK1 ; Unc51-like kinase 1 ; NAFLD ; non-alcoholic fatty liver disease ; GSDII ; glycogen storage disease type II ; LC3 ; microtubule-associated protein 1A/1B-light chain 3 ; C-C3 ; cleaved caspase 3 ; Rap ; rapamycin ; AAV ; adeno-associated virus ; GFP ; green fluorescent protein

刊名：Journal of Hepatology

出版年：2016

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