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在“Elsevier电子期刊”中，命中：1,069条，耗时：0.241881 秒

在所有数据库中总计命中：40,844条

1.Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein

作者：Yeomoon Sim^a ; Gunhyuk Park^a ; Hyeyoon Eo^b ; Eugene Huh^b ; ^c ; Pil Sung Gu^b ; Seon-Pyo Hong^b ; Youngmi Kim Pak^d ; Myung Sook Oh^a ; ^b ; ^{msohok@khu.ac.kr}

关键词：6-OHDA ; 6-hydroxydopamine ; DAT ; dopamine transporter ; ERK ; extracellular signal-regulated kinase ; HPLC ; high-performance liquid chromatography ; MABH ; herbal extract combination of Bupleuri Radix ; Moutan Cortex Radicis and Angelica Dahuricae Radix ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; Nurr1 ; nuclear receptor-related 1 protein ; PBS ; phosphate-buffered saline ; PD ; Parkinson&rsquo ; s disease ; ROP ; ropinirole ; SNpc ; substantia nigra pars compacta ; ST ; striatum ; TH ; tyrosine hydroxylase

刊名：Neuroscience

出版年：2017

2.Possible involvement of Nrf2 and PPARγ up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity

作者：Ayman M. Mahmoud^a ; ^{ayman.mahmoud@science.bsu.edu.eg} ; Mousa O. Germoush^b ; Mohammed F. Alotaibi^c ; Omnia E. Hussein^a

关键词：UMB ; umbelliferone ; PPARγ ; peroxisome proliferator activated receptor gamma ; CP ; cyclophosphamide ; Nrf2 ; nuclear factor erythroid 2-related factor 2 ; iNOS ; inducible nitric oxide synthase ; NF-κB ; nuclear factor-kappa B ; HO-1 ; heme oxygenase 1 ; ROS ; Reactive oxygen species ; Keap 1 ; Kelch-like ECH2-associated protein ; RXR ; retinoid X receptor ; ARE ; antioxidant response element ; ALP ; alkaline phosphatase ; ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; MDA ; malondialdehyde ; NO ; nitr

刊名：Biomedicine & Pharmacotherapy

出版年：2017

3.Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex

作者：Xiaotian Dong^a ; ¹ ; ^{xiaotiandong@zju.edu.cn} ; Xiaoru Su^b ; ¹ ; ^{sxr1240@163.com} ; Jiong Yu^a ; ^{yujiong@zju.edu.cn} ; Jingqi Liu^a ; ^{jqliu97@zju.edu.cn} ; Xiaowei Shi^c ; ^{sxwschy@163.com} ; Qiaoling Pan^a ; ^{qiaolingpan@zju.edu.cn} ; Jinfeng Yang^a ; ^{jinfengjinfengyang@163.com} ; Jiajia Chen^a ; ^{jiajiatale@163.com} ; Lanjuan Li^a ; ^{ljli@zju.edu.cn} ; Hongcui Cao^a ; ^{hccao@zju.edu.cn} ; ^{zjucaohc@163.com}

关键词：HIF2α ; hypoxia-inducible factor 2α ; VHL ; Von Hippel&ndash ; Lindau ; pVHL ; von Hippel Lindau tumor suppressor protein ; CODD ; C-terminal oxygen-dependent degradation domain ; 3D ; three-dimensional ; ARNT ; aryl hydrocarbon receptor nuclear translocator ; HRE ; hypoxia response element ; EPO ; erythropoietin ; VEGF ; vascular endothelial growth factor ; GLUT1 ; glucose transporter 1 ; EDN1 ; endothelin 1 ; TFDP3 ; transcription factor DP family member 3 ; NMR ; nuclear magnetic resonance ; Blastp ; protein&ndash ; protei

刊名：Journal of Molecular Graphics and Modelling

出版年：2017

4.Abnormal mitochondrial dynamics and impaired mitochondrial biogenesis in trigeminal ganglion neurons in a rat model of migraine

作者：Xin Dong^a ; ¹ ; Xinying Guan^a ; ¹ ; Keyan Chen^a ; Shanquan Jin^a ; Chengyun Wang^b ; Lanyun Yan^a ; Zhaochun Shi^a ; Xue Zhang^a ; Ling Chen^c ; Qi Wan^a ; ^{qi_wan@126.com}

关键词：ROS ; reactive oxygen species ; TG ; trigeminal ganglion ; Drp1 ; Dynamin related protein 1 ; Mfn1 ; Mitofusin1 ; mtDNA ; mitochondrial DNA ; PGC-1a ; peroxisome proliferator-activated receptor-gamma coactivator-1a ; NRF1 ; nuclear respiratory factor 1 ; NRF2 ; nuclear respiratory factor 2 ; TFAM ; mitochondrial transcription factor A ; IS ; inflammatory soup

刊名：Neuroscience Letters

出版年：2017

5.Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation

作者：Yimeng Zhang ; Youwei Xu ; Yan Qi ; Lina Xu ; Shasha Song ; Lianhong Yin ; Xufeng Tao ; Yuhong Zhen ; Xu Han ; Xiaodong Ma ; Kexin Liu ; Jinyong Peng ; ^{jinyongpeng2014@163.com} ; ^{jinyongpeng2005@163.com}

关键词：Dox ; doxorubicin ; FXR ; the farnesoid X receptor ; AMPKα ; AMP- activated protein kinase α ; HO-1 ; hemeoxygenase-1 ; GST ; glutathione-s-transferase ; Nrf2 ; NF-E2-related factor 2 ; BUN ; blood urea nitrogen ; Cr ; creatinine ; HMGB1 ; high mobility group box 1 ; NF-κB ; nuclear factor kappa B ; IL-1β ; interleukin-1β ; IL-6 ; interleukin-6 ; TNF-α ; tumor necrosis factor alpha ; siRNA ; small interfering RNA ; H12 ; helix12

刊名：Toxicology

出版年：2017

6.Drug discovery targeting heme-based sensors and their coupled activities

作者：Eduardo Henrique Silva Sousa^a ; ^{eduardohss@dqoi.ufc.br} ; Luiz Gonzaga de Franç ; a Lopes^a ; Gonzalo Gonzalez^b ; Marie-Alda Gilles-Gonzalez^b ; ^{marie-alda.gilles-gonzalez@utsouthwestern.edu}

关键词：Drug discovery ; Heme-based sensor ; Nucleotide cyclase ; Phosphodiesterase ; Histidine protein kinase ; Nuclear receptor

刊名：Journal of Inorganic Biochemistry

出版年：2017

7.TLR4/NF-κB/Ceramide signaling contributes to Ox-LDL-induced calcification of human vascular smooth muscle cells

作者：Yan Song^a ; Menglin Hou^a ; Zhenlin Li^b ; Chufan Luo^c ; Jing-Song Ou^d ; ^e ; Huimin Yu^f ; Jianyun Yan^b ; ^{yanjy790@163.com} ; Lihe Lu^a ; ^{lulihe@mail.sysu.edu.cn}

关键词：Oxidized low density lipoprotein ; Toll like receptor 4 ; Nuclear factor kappa B ; Vascular smooth muscle cells ; Calcification

刊名：European Journal of Pharmacology

出版年：2017

8.Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress

作者：Bing-Hang Li^a ; ¹ ; Fang-Ping He^b ; ¹ ; Xin Yang^c ; Yuan-Wen Chen^a ; ^{drchenyuanwen@163.com} ; Jian-Gao Fan^a ; ^{fattyliver2004@126.com}

关键词：CCL5 ; chemokine (C-C motif) ligand 5 ; RANTES ; regulated upon activation normal T-cell expressed and secreted ; CCR5 ; C-C chemokine receptor type 5 ; NAFLD ; nonalcoholic fatty liver disease ; NASH ; non-alcoholic steatohepatitis ; HFD ; high-fat-diet ; α-SMA ; alpha smooth muscle actin ; TGF-β ; transforming growth factor-β ; FFA ; free fatty acid ; MMP-2 ; matrix metalloproteinase-2 ; C/EBP-β ; CCAAT/enhancer-binding protein-β ; NF-κB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; XBP-1 ; X box

刊名：Translational Research

出版年：2017

9.Quercetin and baicalein suppress monocrotaline-induced hepatic sinusoidal obstruction syndrome in rats

作者：Jiaqi Zhang^a ; Yuchen Sheng^b ; ^{shengych@163.com} ; Liang Shi^a ; Zhiyong Zheng^a ; Minwei Chen^a ; Bin Lu^a ; Lili Ji^a ; ^{lichenyue1307@126.com}

关键词：Sinusoidal obstruction syndrome ; TLRs/NFκB ; Egr1 ; Nrf2 ; MAPKs ; PI3K

刊名：European Journal of Pharmacology

出版年：2017

10.Neuronal low-density lipoprotein receptor-related protein 1 (LRP1) enhances the anti-apoptotic effect of intravenous immunoglobulin (IVIg) in ischemic stroke

作者：Ker Zhing Lok^a ; ^b ; Silvia Manzanero^c ; ^{s.manzanero@uq.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Thiruma V. Arumugam^a ; ^b ; ^d ; ^{phstva@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author}

关键词：APP ; amyloid precursor protein ; BBB ; blood brain barrier ; IFN-γ ; interferon-gamma ; IVIg ; Intravenous immunoglobulin ; I/R ; ischemia and reperfusion ; LDL ; low-density lipoprotein ; LRP1 ; low-density lipoprotein receptor-related protein 1 ; LPS ; lipopolysaccharide ; MAPKs ; mitogen-activated protein kinases ; NF-κB ; Nuclear factor-κB ; OGD ; oxygen and glucose deprivation ; RAP ; receptor associated protein ; TLR ; toll like receptor

刊名：Brain Research

出版年：2016

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