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在“Elsevier电子期刊”中，命中：169条，耗时：小于0.01 秒

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1.Possible roles of long-chain sphingomyelines and sphingomyelin synthase 2 in mouse macrophage inflammatory response

作者：Hideaki Sakamoto^a ; ^{hideaki.sakamoto@shionogi.co.jp} ; Tetsuya Yoshida^a ; Takao Sanaki^b ; Shuhei Shigaki^b ; Hirotoshi Morita^b ; Miki Oyama^a ; Masaru Mitsui^a ; Yoshikazu Tanaka^a ; Toru Nakano^a ; Susumu Mitsutake^c ; ¹ ; Yasuyuki Igarashi^c ; Hiroshi Takemoto^a

关键词：Sphingomyelin synthase 2 ; Long-chain sphingomyelin ; Inflammation

刊名：Biochemical and Biophysical Research Communications

出版年：2017

2.Stressful learning paradigm precludes manifestation of cognitive ability in sphingomyelin synthase-2 knockout mice

作者：Min Wang^a ; ^c ; ^d ; Osamu Uchiumi^a ; Hideo Ogiso^b ; Yuan Shui^a ; Jingyu Zou^a ; ^e ; Chieko Hashizume^b ; Makoto Taniguchi^b ; ^c ; Toshiro Okazaki^b ; Nobuo Kato^a ; ^{kato@kanazawa-med.ac.jp}

关键词：Novel object recognition test ; Context-dependent fear learning ; Morris water maze ; Long-term potentiation ; Paired-pulse facilitation ; Synaptic plasticity

刊名：Behavioural Brain Research

出版年：2017

3.Inhibitors of the sphingomyelin cycle: Sphingomyelin synthases and sphingomyelinases

作者：Mohamad Adada^a ; Chiara Luberto^b ; Daniel Canals^a ; ^{Daniel.Canals@stonybrookmedicine.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：alk-SMase ; alkaline sphingomyelinase ; aSMAse ; acid sphingomyelinase ; ATRA ; all-trans retinoic acid ; BMP ; bismonoacylglycerophosphate ; CAD ; cationic amphiphilic drugs ; CerS ; (dihydro)ceramide synthases ; D609 ; tricyclodecan-9-yl-xanthogenate ; DAG ; diacylglycerol ; IL ; interleukin ; L-aSMAse ; lysosomal-aSMase ; LCD ; lysosomal cell death ; LDLs ; low-density lipoproteins ; LPS ; ly&ndash ; popolysaccharide ; Ma-nSMase ; mitochondrial associated nSMase ; MDR ; multidrug resistant ; NPD ; Niemman&ndash ; Pick disease

刊名：Chemistry and Physics of Lipids

出版年：2016

4.Characterization of the role of sphingomyelin synthase 2 in glucose metabolism in whole-body and peripheral tissues in mice

作者：Masayuki Sugimoto^a ; ^b ; Yoichi Shimizu^c ; ^d ; Songji Zhao^e ; Naoyuki Ukon^e ; Ken-ichi Nishijima^a ; ^c ; Masato Wakabayashi^b ; Takeshi Yoshioka^b ; Kenichi Higashino^b ; Yoshito Numata^b ; Tomohiko Okuda^f ; Nagara Tamaki^g ; Hisatoshi Hanamatsu^h ; Yasuyuki Igarashi^h ; Yuji Kuge^a ; ^c ; ^{kuge@ric.hokudai.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：SM ; sphingomyelin ; SMS ; sphingomyelin synthase ; Cer ; ceramide ; CerS ; ceramide synthase ; S1P ; sphingosine 1 phosphate ; LC/ESI-MS/MS ; liquid chromatography/electrospray ionization-tandem mass spectrometry ; VLCFA ; very long-chain fatty acid ; HexCer ; hexosylceramide ; DhCer ; dihydroceramide ; 18F-FDG ; 18F-2-fluoro-2-deoxy-d-glucose ; OGTT ; oral glucose tolerance test ; ITT ; insulin tolerance test ; GSIS ; glucose stimulated-insulin secretion ; HOMA-R ; homeostasis model assessment-insulin resistance ; T2DM

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2016

5.Regulation of sphingomyelin metabolism

作者：Kamil Bienias^a ; Anna Fiedorowicz^a ; ^b ; Anna Sadowska^a ; Sławomir Prokopiuk^a ; Halina Car^a ; ^{zfarmdosw@umb.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：α-syn ; α-synuclein ; Aβ ; amyloid β ; AD ; Alzheimer disease ; APP ; amyloid precursor protein ; a-SMase ; acid sphingomyelinase ; alk-SMase ; Alkaline SMase ; Cer ; ceramide ; CERT ; ceramide transfer protein ; CSF ; cerebrospinal fluid ; D609 ; tricyclodecan-9-yl-xanthogenate ; DAG ; diacyglicerol ; ER ; endoplasmic reticulum ; FasL ; Fas ligand ; FIASMA ; Functional Inhibitor of Acid SphingoMyelinAse ; GSH ; glutathione ; IR ; ischemia/reperfusion ; l-SMaze ; lysosome sphingomyelinase ; MA-nSMase ; mitochondrial sphingomyelin

刊名：Pharmacological Reports

出版年：2016

6.Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors

作者：Ya-li Li^a ; Xiang-yu Qi^a ; Hui Jiang^b ; Xiao-dong Deng^a ; Yan-ping Dong^d ; Ting-bo Ding^a ; Lu Zhou^a ; Peng Men^a ; Yong Chu^a ; Ren-xiao Wang^c ; ^{wangrx@mail.sioc.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Xian-cheng Jiang^a ; ^b ; ^{xjiang@downstate.edu" class="auth_mail" title="E-mail the corresponding author} ; De-yong Ye^a ; ^{dyye@shmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：SM ; sphingomyelin ; SMS ; sphingomyelin synthase ; PC ; phosphatidylcholine ; DAG ; diacylglycerol ; TM ; transmembrane ; hSMS1 ; human sphingomyelin synthase 1 ; His ; histidine ; Asp ; aspartic acid ; SAPA ; 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamide ; SAR ; structure&ndash ; activity relationships ; Phe ; phenylalanine ; Leu ; leucine ; Ala ; alanine ; Arg ; arginine ; Trp ; tryptophane ; Tyr ; tyrosine ; C6-NBD-Cer ; 6-((N-(7-nitrobenz-2-oxa-1 ; 3-diazol-4-yl)amino)hexanoyl)-sphingosine ; DMPC ; 1 ; 2-dimyristoyl-sn-glycero-3-ph

刊名：Bioorganic & Medicinal Chemistry

出版年：2015

7.Cholesterol-dependent increases in glucosylceramide synthase activity in Niemann-Pick disease type C model cells: Abnormal trafficking of endogenously formed ceramide metabolites by inhibition of the enzyme

作者：Naohiro Hashimoto¹ ; Ikiru Matsumoto¹ ; Hiromasa Takahashi ; Hitomi Ashikawa ; Hiroyuki Nakamura ; ^{nakahiro@faculty.chiba-u.jp" class="auth_mail" title="E-mail the corresponding author} ; Toshihiko Murayama

关键词：Niemann-Pick disease type C ; Cholesterol ; Glucosylceramide synthase ; Sphingomyelin ; Vesicular trafficking

刊名：Neuropharmacology

出版年：2016

8.Caged ceramide 1-phosphate (C1P) analogs: Novel tools for studying C1P biology

作者：Antonio Gomez-Muñ ; oz ; ^{antonio.gomez@ehu.es" class="auth_mail" title="E-mail the corresponding author} ; Patricia Gangoiti ; Io-Guané ; Rivera ; Natalia Presa ; Ana Gomez-Larrauri ; Marta Ordoñ ; ez

关键词：Akt (PKB) ; protein kinase ; B BHNB ; 4-bromo-5-hydroxy-2-nitrobenzhydryl ; BMDM ; bone marrow-derived macrophages ; CerK ; ceramide kinase ; C1P ; ceramide 1-phosphate ; cPLA2 ; calcium-dependent cytosolic phospholipase 2 ; DECM ; 7-(N ; N-diethylamino)coumarin ; ERK ; extracellularly regulated kinases ; GLUT ; glucose transporter ; iNOS ; inducible nitric oxide synthase ; PKC ; protein kinase C ; PI3K ; phosphatidylinositol 3-kinase ; PTX ; pertussis toxin ; ROS ; reacfive oxygen species ; SMase ; sphingomyelinase ; SPT ; ser

刊名：Chemistry and Physics of Lipids

出版年：2016

9.Histological analyses by matrix-assisted laser desorption/ionization-imaging mass spectrometry reveal differential localization of sphingomyelin molecular species regulated by particular ceramide synthase in mouse brains

作者：Masayuki Sugimoto^a ; ^b ; Yoichi Shimizu^c ; Takeshi Yoshioka^a ; Masato Wakabayashi^a ; Yukari Tanaka^d ; Kenichi Higashino^a ; Yoshito Numata^a ; Shota Sakai^e ; Akio Kihara^f ; Yasuyuki Igarashi^e ; Yuji Kuge^b ; ^c ; ^{kuge@ric.hokudai.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：SM ; sphingomyelin ; SMS ; sphingomyelin synthase ; Cer ; ceramide ; CerS ; ceramide synthase ; LC/ESI-MS/MS ; liquid chromatography/electrospray ionization-tandem mass spectrometry ; IMS ; imaging mass spectrometry ; ISH ; in situ hybridization ; MALDI ; matrix-assisted laser desorption/ionization ; FTICR ; Fourier transform ion cyclotron resonance ; VLCFA ; very long-chain fatty acid ; HexCer ; hexosylceramide ; GlcCer ; glucosylceramide ; GalCer ; galactosylceramide ; LacCer ; lactosylceramide

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2015

10.Inhibitors of sphingosine-1-phosphate metabolism (sphingosine kinases and sphingosine-1-phosphate lyase)

作者：Pol Sanllehí ; ^a ; ^b ; José ; -Luis Abad^a ; Josefina Casas^a ; Antonio Delgado^a ; ^b ; ^{delgado@rubam.net" class="auth_mail" title="E-mail the corresponding author}

关键词：3-kdhSo ; 3-ketodihydrosphingosine ; aSMase ; acid sphingomyelinase ; aCDase ; acid ceramidase ; C1P ; ceramide-1-phosphate ; Cer ; ceramide ; CerK ; ceramide kinase ; CerS ; ceramide synthases ; CerT ; ceramide transporter protein ; cPLA2a ; cytosolic phospholipase A2 ; Des1 ; dhCer desaturase ; dhCer ; dihydroceramide ; dhSo ; dihydrosphingosine (sphinganine) ; ER ; endoplasmic reticulum ; FAPP2 ; four-phosphate adaptor protein ; GC ; glucosyl ceramide ; GCS ; glucosyl ceramide synthase ; GSL ; complex glycosphingolipids ; HDL

刊名：Chemistry and Physics of Lipids

出版年：2016

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