搜索页_1-methyl-4-phenylpyridinium

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在“Elsevier电子期刊”中，命中：501条，耗时：0.0170212 秒

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1.The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA

作者：Jolanta Konieczny^a ; ^{koniecz@if-pan.krakow.pl} ; Anna Czarnecka^a ; ^&dagger ; ; Tomasz Lenda^a ; Kinga Kamińska^a ; Lucyna Antkiewicz-Michaluk^b

关键词：DA ; dopamine ; DOPAC ; dihydroxyphenylacetic acid ; HVA ; homovanilic acid ; MPP+ ; 1-methyl-4-phenylpyridinium ion ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; PD ; Parkinson&rsquo ; s disease ; SN ; substantia nigra ; SNc ; substantia nigra pars compacta ; SNr ; substantia nigra pars reticulata ; UPS ; ubiquitin&ndash ; proteasome system

刊名：Neuroscience

出版年：2017

2.Resveratrol attenuates MPP⁺-induced mitochondrial dysfunction and cell apoptosis via AKT/GSK-3β pathway in SN4741 cells

作者：Weijun Zeng^a ; ¹ ; Wei Zhang^b ; ^c ; ¹ ; Fangfang Lu^a ; Li Gao^a ; Guodong Gao^a ; ^{gaogd1954@163.com}

关键词：Res ; Resveratrol ; MPP+ ; 1-methyl-4-phenylpyridinium ; PD ; Parkinson&rsquo ; s disease ; GSK-3 ; Glycogen synthase kinase-3 ; GSK-3β ; Glycogen synthase kinase-3 beta ; AKT ; Protein kinase B ; MMP ; Mitochondrial membrane potential ; PI3K ; Phosphatidylinositol 3-kinase ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; MTT ; 3-(4 ; 5-dimethylthiazol-2yl)-2 ; 5-diphenyltetrazolium bromide

刊名：Neuroscience Letters

出版年：2017

3.Effects of frequently used pharmaceutical excipients on the organic cation transporters 1-3 and peptide transporters 1/2 stably expressed in MDCKII cells

作者：Marcus Otter ; Stefan Oswald ; Werner Siegmund ; Markus Keiser ; ^{markus.keiser@uni-greifswald.de}

关键词：Pharmaceutical excipients ; Solubilizing agents ; Drug transporter ; Uptake transport ; Organic cation transporter (OCT) ; Peptide transporter (PEPT) ; Polyethylene glycol (PEG) ; Hydroxypropyl-β-cyclodextrin ; Solutol HS 15 (macrogol 15 hydroxystearate ; polyoxyl 15 hydroxystearate) ; Cremophor ; Tween (polysorbate) ; Kolliphor (poloxamer) ; MDCK cells ; In vitro ; Cell model ; Competition assay ; Inhibition assay

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

4.MPP⁺ inhibits mGluR1/5-mediated long-term depression in mouse hippocampus by calpain activation

作者：Junyao Li^a ; ¹ ; Hui Chen^a ; ¹ ; Shengbing Wu^a ; Yuefa Cheng^b ; Qinglin Li^a ; Jing Wang^a ; ^{wangjing2161@126.com} ; Guoqi Zhu^a ; ^{guoqizhu@gmail.com}

关键词：MPP+ ; Calpain ; DHPG ; Hippocampus ; Long-term depression

刊名：European Journal of Pharmacology

出版年：2017

5.In-vivo evidence that high mobility group box 1 exerts deleterious effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and Parkinson's disease which can be attenuated by glycyrrhizin

作者：Matteo Santoro^a ; ¹ ; Walter Maetzler^b ; ^c ; ¹ ; Petros Stathakos^a ; Heather L. Martin^a ; Markus A. Hobert^b ; ^c ; Tim W. Rattay^b ; ^c ; Thomas Gasser^b ; ^c ; John V. Forrester^a ; ^d ; ^e ; Daniela Berg^b ; ^c ; Kevin J. Tracey^f ; Gernot Riedel^a ; Peter Teismann^a ; ^{pteismann@gmx.de" class="auth_mail" title="E-mail the corresponding author}

关键词：COX ; cyclooxygenase ; CSF ; Cerebrospinal fluid ; DOPAC ; 3 ; 4-Dihydroxyphenylacetic acid ; GFAP ; glial fibrillary acidic protein ; H&Y ; Hoehn & Yahr ; HMGB1 ; high-mobility group box 1 ; HVA ; homovanillic acid ; MPP+ ; ; 1-methyl-4-phenylpyridinium ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; OD ; optical density ; PD ; Parkinson's disease ; RAGE ; receptor for advanced glycation endproducts ; SNpc ; substantia nigra pars compacta ; TH ; tyrosine-hydroxylase ; TNF-α ; tumour necrosis factor-alpha ; Wt ; wil

刊名：Neurobiology of Disease

出版年：2016

6.Alteration of nuclear factor-kappaB pathway promote neuroinflammation depending on the functions of estrogen receptors in substantia nigra after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment

作者：Soham Mitra^a ; ^{soham_envs@yahoo.co.in" class="auth_mail" title="E-mail the corresponding author} ; Nabanita Ghosh^a ; ^{ngdiya@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Priyobrata Sinha^b ; ^{priyobiochem@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Nilkanta Chakrabarti^b ; ^{nilchakra@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Arindam Bhattacharyya^a ; ^{arindam19@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; ^{arigene@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：PD ; Parkinson's disease ; SN ; substantia nigra ; Iba1 ; ionized calcium binding adaptor molecule 1 ; MPP+ ; 1-methyl-4-phenylpyridinium ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; TNF-α ; tumor necrosis factor-alpha ; b.w. ; body weight ; GFAP ; glial fibrillary acidic protein ; NF-κB ; nuclear factor kappa B

刊名：Neuroscience Letters

出版年：2016

7.Protective effects of DJ-1 medicated Akt phosphorylation on mitochondrial function are promoted by Da-Bu-Yin-Wan in 1-methyl-4-phenylpyridinium-treated human neuroblastoma SH-SY5Y cells

作者：Yi Zhang^a ; ^f ; ¹ ; ^{zy_dalian@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; ^{yizhang@bucm.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Xiao-Gang Gong^a ; ^g ; ¹ ; Zhen-Zhen Wang^b ; Hong-Mei Sun^a ; ^{hm.sun@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Zhen-Yu Guo^a ; Cong Gai^a ; Jing-Hong Hu^c ; Ling Ma^a ; Ping Li^d ; Nai-Hong Chen^b ; ^e

关键词：Parkinson's disease ; Mitochondrial dysfunction ; DJ-1 ; Akt ; Phosphorylation ; Da-Bu-Yin-Wan

刊名：Journal of Ethnopharmacology

出版年：2016

8.Involvement of IGF-1 receptor signaling pathway in the neuroprotective effects of Icaritin against MPP⁺-induced toxicity in MES23.5 cells

作者：Ming-Chun Jiang^a ; ^b ; ^c ; ^d ; Xiao-Han Chen^a ; ^b ; Xia Zhao^a ; ^b ; Xue-Jie Zhang^a ; ^b ; Wen-Fang Chen^a ; ^b ; ^{chenwenfangqd@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Icaritin ; 1-Methyl-4-phenylpyridinium ion ; Insulin-like growth factor-1 receptor ; Akt ; ERK1/2 ; MES23.5 cells

刊名：European Journal of Pharmacology

出版年：2016

9.Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson’s disease

作者：H. Sun^a ; R. Liang^a ; B. Yang^a ; Y. Zhou^a ; M. Liu^a ; F. Fang^a ; J. Ding^a ; Y. Fan^a ; ^{Yfan@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; G. Hu^a ; ^b ; ^c ; ^d ; ^{Ghu@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：AQP4 ; aquaporin-4 ; CD11b-ir ; CD11b-immunoreactive ; CNS ; central nervous system ; DIV ; day in vitro ; DMSO ; dimethyl sulfoxide ; EAE ; experimental autoimmune encephalomyelitis ; ELISA ; enzyme-linked immunosorbent assay ; GFAP ; glial fibrillary acidic protein ; GFAP-ir ; GFAP-immunoreactive ; IL-1β ; interleukin-1β ; KO ; knockout ; LDH ; lactate dehydrogenase ; MPP+ ; 1-methyl-4-phenylpyridinium ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; MPTP/p ; MPTP/probenecid ; PD ; Parkinson disease ; qRT-PCR ; quantit

刊名：Neuroscience

出版年：2016

10.Metformin, besides exhibiting strong in vivo anti-inflammatory properties, increases mptp-induced damage to the nigrostriatal dopaminergic system

作者：Afrah A.K. Ismaiel ; Ana M. Espinosa-Oliva ; Martiniano Santiago ; Albert Garcí ; a-Quintanilla ; Marí ; a J. Oliva-Martín ; Antonio J. Herrera ; José ; L. Venero ; Rocí ; o M. de Pablos ; ^{depablos@us.es" class="auth_mail" title="E-mail the corresponding author}

关键词：AMPK ; adenosine monophosphate-activated protein kinase ; BBB ; blood brain barrier ; cAMP ; dibutyryl cyclic adenosine monophosphate ; DA ; dopamine ; DAT ; dopamine transporter ; DOPAC ; 3 ; 4-dihydroxyphenylacetic acid ; FBS ; fetal bovine serum ; HPLC ; high-performance liquid chromatography ; iNOS ; inducible nitric oxide synthase ; IL ; interleukine ; MPP+ ; ; 1-methyl-4-phenylpyridinium ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; OCT ; organic cation transport ; PD ; Parkinson's disease ; PINK1 ; PTEN-i

刊名：Toxicology and Applied Pharmacology

出版年：2016

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