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在“Elsevier电子期刊”中，命中：13条，耗时：小于0.01 秒

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1.Characterizing drug-metabolizing enzymes and transporters that are bona fide CAR-target genes in mouse intestine

作者：Shinhee Park^&dagger ; ; Sunny Lihua Cheng^&dagger ; ; Julia Yue Cui ; ^{juliacui@uw.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Aldh ; aldehyde dehydrogenase ; Asbt ; solute carrier family 10 ; member 2 (apical sodium/bile acid cotransporter) ; CAR ; constitutive androstane receptor ; cDNA ; complementary DNA ; CITCO ; 6-(4-chlorophenyl)imidazo [2 ; 1-b](1 ; 3)thiazole-5-carbaldehyde O-(3 ; 4-dichlorobenzyl)oxime ; Cq ; quantification cycle ; Cyp ; cytochrome P450 ; ddCq ; delta delta Cq ; DPGs ; drug-processing genes (genes that encodes drug metabolizing enzymes or transporters) ; Gst ; glutathione S-trasnferase ; H3 ; Histone 3 ; hCAR ; human const

刊名：Acta Pharmaceutica Sinica B

出版年：2016

2.Insights into CYP2B6-mediated drug-drug interactions

作者：William D. Hedrich ; Hazem E. Hassan ; Hongbing Wang ; ^{hwang@rx.umaryland.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CAR ; constitutive androstane receptor ; C/EBP ; CCAAT/enhancer-binding protein ; CHOP ; cyclophosphamide&ndash ; doxorubicin&ndash ; vincristine&ndash ; prednisone ; CITCO ; (6-(4-chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehyde-O-(3 ; 4-dichlorobenzyl)oxime) ; COUP-TF ; chicken ovalbumin upstream promoter-transcription factor ; CPA ; cyclophosphamide ; 4-OH-CPA ; 4-hydroxycyclophosphamide ; CYP ; cytochrome P450 ; DDI ; drug&ndash ; drug interaction ; DEX ; dexamethasone ; EFV ; efavirenz ; E2 ; estradiol ; ERE ; estroge

刊名：Acta Pharmaceutica Sinica B

出版年：2016

3.Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes

作者：Benjamin A. Kandel^a ; ^b ; Maria Thomas^a ; ^b ; Stefan Winter^a ; ^b ; Georg Damm^c ; Daniel Seehofer^c ; Oliver Burk^a ; ^b ; Matthias Schwab^a ; ^b ; ^d ; Ulrich M. Zanger^a ; ^b ; ^{uli.zanger@ikp-stuttgart.de" class="auth_mail" title="E-mail the corresponding author}

关键词：ADME ; absorption ; distribution ; metabolism ; excretion ; CAR ; constitutive androstane receptor (NR1I3) ; CITCO ; 6-(4-Chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehyde O-(3 ; 4-dichlorobenzyl)oxime ; CYP ; cytochrome P450 ; DMET ; drug metabolism and transport ; PHH ; primary human hepatocytes ; PPARα ; peroxisome proliferator-activated receptor alpha (NR1C1) ; PXR ; pregnane X receptor (NR1I2) ; WY14 ; 643 ; [[4-chloro-6-[(2 ; 3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-acetic acid

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2016

4.Mechanisms of xenobiotic receptor activation: Direct vs. indirect

作者：Bryan Mackowiak ; Hongbing Wang ; ^{hwang@rx.umaryland.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AhR ; aryl hydrocarbon receptor ; ARNT ; aryl hydrocarbon nuclear translocator ; CAR ; constitutive androstane receptor ; CCRP ; cytoplasmic retention protein ; CITCO ; 6-(4-chlorophenyl)imidazo [2 ; 1-beta][1 ; 3]thiazole-5-carbaldehyde-O-(3 ; 4-dichlorobenzyl)oxime ; DBD ; DNA-binding domain ; EGFR ; epidermal growth factor receptor ; ERK ; extracellular signal-regulated kinase ; FRET ; fluorescence resonance energy transfer ; GRIP1 ; glucocorticoid receptor interacting protein 1 ; HSP ; heat-shock protein ; LBD ; ligand-

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2016

5.Constitutive androstane receptor (Car)-driven regeneration protects liver from failure following tissue loss

作者：Christoph Tschuor¹ ; Ekaterina Kachaylo¹ ; Pë ; rparim Limani¹ ; Dimitri A. Raptis¹ ; Michael Linecker¹ ; Yinghua Tian¹ ; Uli Herrmann² ; Kamile Grabliauskaite¹ ; Achim Weber³ ; Amedeo Columbano⁴ ; Rolf Graf¹ ; Bostjan Humar¹ ; ^&dagger ; ; ^{bostjan.humar@usz.ch" class="auth_mail" title="E-mail the corresponding author} ; Pierre-Alain Clavien¹ ; ^&dagger ; ; ^{clavien@access.uzh.ch" class="auth_mail" title="E-mail the corresponding author}

关键词：CAR ; constitutive androstane receptor ; CITCO ; (6-(4-chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehydeO-(3 ; 4-dichlorobenzyl)oxime) ; eHx ; extended hepatectomy ; huCAR ; humanized CAR ; SFSS ; small-for-size syndrome ; sHx ; standard hepatectomy ; TCP ; 1 ; 4-bis(2-(3 ; 5-dichloropyridyloxy))benzene

刊名：Journal of Hepatology

出版年：2016

6.Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells

作者：Daochuan Li^a ; Bryan Mackowiak^a ; Timothy G. Brayman^b ; Michael Mitchell^b ; Lei Zhang^c ; Shiew-Mei Huang^c ; Hongbing Wang^a ; ^{hwang@rx.umaryland.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CAR ; constitutive androstane receptor ; CITCO ; 6-(4-chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehyde-O-(3 ; 4-dichlorobenzyl)oxime ; CYP ; cytochrome P450 ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; GPR56 ; G protein-coupled receptor 56 ; GPX2 ; glutathione peroxidase 2 ; HPH ; human primary hepatocytes ; Nrf2 ; nuclear factor (erythroid-derived 2)-like 2 ; PB ; phenobarbital ; PXR ; pregnane X receptor ; TCPOBOP ; 1 ; 4-bis[2-(3 ; 5-dichloropyridyloxy)]benzene ; TEK ; angiopoietin-1 receptor

刊名：Biochemical Pharmacology

出版年：2015

7.Fetal bovine serum and human constitutive androstane receptor: Evidence for activation of the SV23 splice variant by artemisinin, artemether, and arteether in a serum-free cell culture system

作者：Aik Jiang Lau ; Thomas K.H. Chang ; ^{thomas.chang@ubc.ca" class="auth_mail}

关键词：CAR ; constitutive androstane receptor ; CAS ; Chemical Abstracts Service ; CITCO ; 6-(4-chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehyde O-(3 ; 4-dichlorobenzyl)oxime ; CS-FBS ; charcoal-stripped ; dextran-treated fetal bovine serum ; DEHP ; di-(2-ethylhexyl)phthalate ; DMSO ; dimethyl sulfoxide ; FBS ; fetal bovine serum ; hCAR ; human constitutive androstane receptor ; hRXR伪 ; human retinoid X receptor alpha ; MEM ; Minimum Essential Medium ; MEM-RS ; Minimum Essential Medium-Reduced Serum ; RXR伪 ; retinoid X r

刊名：Toxicology and Applied Pharmacology

出版年：1 June 2014

8.Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system

作者：Prapapan Pimkaew ; Jenni K¨¹blbeck ; Aleksanteri Petsalo ; Jouni Jukka ; Apichart Suksamrarn ; Risto Juvonen ; Seppo Auriola ; Pawinee Piyachaturawat ; Paavo Honkakoski

关键词：ACN ; acetonitrile ; AhR ; aryl hydrocarbon receptor ; CAR ; constitutive androstane receptor ; CITCO ; 6-(4-chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehyde O-(3 ; 4-dichloro-benzyl)oxime ; CYP ; cytochrome P450 ; DMSO ; dimethyl sulfoxide ; GAPDH ; glyseraldehy

刊名：Toxicology in Vitro

出版年：2013

9.Dual roles of nuclear receptor liver X receptor ¦Á (LXR¦Á) in the CYP3A4 expression in human hepatocytes as a positive and negative regulator

作者：Keisuke Watanabe ; Kaori Sakurai ; Yuri Tsuchiya ; Yasushi Yamazoe ; Kouichi Yoshinari

关键词：24S-HC ; 24(S)-hydroxycholesterol ; CAR ; constitutive active/androstane receptor ; CITCO ; 6-(4-chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehyde-O-(3 ; 4-dichlorobenzyl)oxime ; DMSO ; dimethyl sulfoxide ; DR-4 ; direct repeat separated by 4 nucleotides ; EMSA

刊名：Biochemical Pharmacology

出版年：2013

10.Effects of nuclear receptor transactivation on steroid hormone synthesis and gene expression in porcine Leydig cells

作者：Matthew A. Gray ; E. James Squires ; ^{jsquires@uoguelph.ca}

关键词：16-Androstenes ; Nuclear receptors ; Leydig cells ; Transcription ; Steroidogenesis

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2013

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