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在“Elsevier电子期刊”中，命中：3,268条，耗时：0.0269614 秒

在所有数据库中总计命中：10,618条

1.Design, synthesis and biological evaluation of (E)-3,4-dihydroxystyryl 4-acylaminophenethyl sulfone, sulfoxide derivatives as dual inhibitors of HIV-1 CCR5 and integrase

作者：Yixing Sun^a ; ¹ ; Weisi Xu^b ; ¹ ; Ningning Fan^a ; Xuefeng Sun^a ; Xianling Ning^a ; Liying Ma^b ; ^{mal@chinaaids.cn} ; Junyi Liu^a ; ^c ; ^{jyliu@bjmu.edu.cn} ; Xiaowei Wang^a ; ^{xiaoweiwang@bjmu.edu.cn}

关键词：HIV dual inhibitors ; CCR5 receptor ; HIV integrase ; Sulfones ; Sulfoxides

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction

作者：Feng-Hua Zhang^a ; Bikash Debnath^b ; Zhong-Liang Xu^a ; Liu-Meng Yang^c ; Li-Rui Song^a ; Yong-Tang Zheng^c ; Nouri Neamati^b ; ^{neamati@umich.edu} ; Ya-Qiu Long^a ; ^{yqlong@simm.ac.cn}

关键词：HIV-1 integrase ; Allosteric inhibitor ; LEDGF/p75 ; Dimerization ; 3-Hydroxypicolinamide

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Enhanced potency of bivalent small molecule gp41 inhibitors

作者：Vladimir Sofiyev^a ; Hardeep Kaur^a ; Beth A. Snyder^c ; Priscilla A. Hogan^c ; Roger G. Ptak^c ; Peter Hwang^d ; Miriam Gochin^a ; ^b ; ^{miriam.gochin@tu.edu}

关键词：HIV-1 gp41 ; Hydrophobic pocket ; Fusion inhibition ; Peptidomimetic inhibitors ; Bivalent inhibitors ; Fluorescence ; Surface plasmon resonance ; Kinetics ; Cooperativity

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.Identifications of drug resistance mutations among antiretroviral treatment naive HIV-1 patients in Peninsular Malaysia

作者：Rozainanee Mohd Zain ; ^{rozainanee@yahoo.com} ; Nabila Ibrahim ; Suriani Ismail ; Jeyanthi Suppiah ; Nor Aziyah Mat Rahim ; Ravindran Thayan

关键词：HIV ; Resistance ; Malaysia ; Antiretroviral treatment naive

刊名：Asian Pacific Journal of Tropical Medicine

出版年：2017

5.Catalytic synthesis of α-amino chromone phosphonates and their antimicrobial, toxicity and potential HIV-1 RT inhibitors based on silico screening

作者：Abosede Oluwabukola Jaiyeola^a ; K. Anand^a ; ^b ; ^{organicanand@gmail.com} ; K. Kasumbwe^c ; M. Ramesh^d ; R.M. Gengan^a ; ^{genganrm@dut.ac.za}

关键词：Boron nitride ; Kabachnik-Fields reaction ; Molecular docking ; Antimicrobial ; HIV-1 reverse transcriptase

刊名：Journal of Photochemistry and Photobiology B: Biology

出版年：2017

6.Body composition and metabolic outcomes after 96 weeks of treatment with ritonavir-boosted lopinavir plus either nucleoside or nucleotide reverse transcriptase inhibitors or raltegravir in patients with HIV with virological failure of a standard first-line antiretroviral therapy regimen: a substudy of the randomised, open-label, non-inferiority SEC

作者：Prof Mark A Boyd ; MD^a ; ^b ; ^{mark.boyd@adelaide.edu.au} ; Janaki Amin ; PhD^b ; Patrick W G Mallon ; PhD^c ; Nagalingeswaran Kumarasamy ; MD^d ; Johan Lombaard ; MD^e ; Prof Robin Wood ; PhD^f ; Prof Ploenchan Chetchotisakd ; MD^g ; Prof Praphan Phanuphak ; PhD^h ; Lerato Mohapi ; MDⁱ ; Iskandar Azwa ; MD^j ; Waldo H Belloso ; MD^k ; Prof Jean-Michel Molina ; PhD^l ; Prof Jennifer Hoy ; MD^m ; Cecilia L Moore ; MIPH^b ; Prof Sean Emery ; PhD^b ; Prof David A Cooper ; FAA^b ; on behalf of the SECOND-LINE Study Group^&dagger ;

刊名：The Lancet HIV

出版年：2017

7.Mitochondrial defects arise from nucleoside/nucleotide reverse transcriptase inhibitors in neurons: Potential contribution to HIV-associated neurocognitive disorders

作者：Kui-Ming Hung^a ; ^b ; Pei-Chun Chen^b ; Han-Chieh Hsieh^c ; Marcus J Calkins^a ; ^{mjcalkins@mail.ncku.edu.tw}

关键词：NRTI ; nucleoside/nucleotide reverse transcriptase inhibitor ; HAND ; HIV-associated neurocognitive disorders ; cART ; combination antiretroviral therapy ; pol γ ; polymerase γ ; mtDNA ; mitochondrial DNA ; ddI ; didanosine ; AZT ; zidovudine ; FTC ; emtricitabine ; TDF ; tenofovir ; ddC ; zalcitabine ; d4T ; stavudine ; 3TC ; lamivudine ; ABC ; abacavir ; PGC-1α ; peroxisome proliferator-activated receptor γ coactivator 1α ; mtUPR ; mitochondrial unfolded protein response ; CO1 ; Cytochrome oxidase I ; ND1 ; NADH Dehydrogenase

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

8.3D-QSAR and molecular docking studies on HIV protease inhibitors

作者：Jianbo Tong ; ^{jianbotong@aliyun.com} ; Yingji Wu ; Min Bai ; Pei Zhan

关键词：Cyclic-urea derivatives ; 3D-QSAR ; CoMSIA ; Molecular docking

刊名：Journal of Molecular Structure

出版年：2017

9.HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation

作者：Patrick J. Gannon^&lowast ; ; ^&dagger ; ; Cagla Akay-Espinoza^&dagger ; ; Alan C. Yee^&dagger ; ; Lisa A. Briand^&Dagger ; ; Michelle A. Erickson^&dagger ; ; Benjamin B. Gelman^§ ; ; Yan Gao^¶ ; ; Norman J. Haughey^‖ ; M. Christine Zink^&lowast ; &lowast ; ; Janice E. Clements^&lowast ; &lowast ; ; Nicholas S. Kim^&dagger ; ; Gabriel Van De Walle^&dagger ; ; Brigid K. Jensen^&dagger ; ; Robert Vassar^&dagger ; &dagger ; ; R. Christopher Pierce^&Dagger ; &Dagger ; ; Alexander J. Gill^§ ; § ; ; Dennis L. Kolson^§ ; § ; ; J. Alan Diehl^¶ ; ; Joseph L. Mankowski^‖ ; Kelly L. Jordan-Sciutto^&dagger ; ; ^{jordank@upenn.edu}

刊名：The American Journal of Pathology

出版年：2017

10.Design, synthesis and anti-HIV-1 RT evaluation of 2-(benzyl(4-chlorophenyl)amino)-1-(piperazin-1-yl)ethanone derivatives

作者：Subhash Chander^a ; Ping Wang^b ; Penta Ashok^a ; Liu-Meng Yang^b ; Yong-Tang Zheng^b ; ^{zhengyt@mail.kiz.ac.cn} ; Murugesan Sankaranarayanan^a ; ^{murugesan@pilani.bits-pilani.ac.in}

关键词：Enzymatic assay ; Wild strain ; Reverse transcriptase ; Docking ; Cytotoxicity

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

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