搜索页_HIV-1+fusion+inhibitor

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在“Elsevier电子期刊”中，命中：267条，耗时：0.0369824 秒

在所有数据库中总计命中：2,230条

1.Enfuvirtide−PEG conjugate: A potent HIV fusion inhibitor with improved pharmacokinetic properties

作者：Shuihong Cheng^a ; ^b ; ¹ ; Yan Wang^c ; ¹ ; Zhenxing Zhang^a ; ^d ; Xun Lv^a ; George F. Gao^a ; ^e ; Yiming Shao^c ; Liying Ma^c ; ^{mal@chinaaids.cn" class="auth_mail" title="E-mail the corresponding author} ; Xuebing Li^a ; ^b ; ^e ; ^{lixb@im.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Conjugation ; Enfuvirtide ; Fusion inhibitor ; Human immunodeficiency virus ; Pharmacokinetics ; Poly(ethylene glycol)

刊名：European Journal of Medicinal Chemistry

出版年：2016

2.Insights into the Functions of M-T Hook Structure in HIV Fusion Inhibitor Using Molecular Modeling

作者：Jianjun Tan ; ^{tanjianjun@bjut.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Hongling Yuan ; Chunhua Li ; ^{chunhuali@bjut.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Xiaoyi Zhang ; Cunxin Wang

关键词：Molecular dynamic simulation ; MM-PB/GBSA ; Binding free energy ; HIV-1 ; Fusion inhibitors

刊名：Computational Biology and Chemistry

出版年：2016

3.Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy

作者：Ayako Hoshi^a ; Takeshi Sakamoto^a ; ^{sakamoto@josai.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Jun Takayama^a ; Meiyan Xuan^a ; Mari Okazaki^a ; Tracy L. Hartman^b ; Robert W. Buckheit Jr.^b ; Christophe Pannecouque^c ; Mark Cushman^d ; ^{cushman@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ADAM ; alkenyldiarylmethane ; NNRTI ; non-nucleoside reverse transcriptase inhibitor ; RT ; reverse transcriptase ; HIV-1 ; human immunodeficiency virus type 1 ; AIDS ; acquired immune deficiency syndrome ; ART ; antiretroviral therapy ; NRTI ; nucleoside reverse transcriptase inhibitor ; PI ; protease inhibitor ; INI ; integrase inhibitors ; FI ; fusion inhibitor ; CCR5I ; CC chemokine receptor inhibitor ; dNTPs ; deoxynucleoside triphosphate ; AZT ; azidothymidine (zidovudine) ; EDCI ; 1-(3-dimethylaminopropyl)-3-ethylc

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.Definition of an 18-mer Synthetic Peptide Derived from the GB virus C E1 Protein as a New HIV-1 Entry Inhibitor

作者：M.J. Gó ; mara^a ; ^{mariajose.gomara@iqac.csic.es" class="auth_mail" title="E-mail the corresponding author} ; V. Sá ; nchez-Merino^b ; A. Paú ; s^a ; A. Merino-Mansilla^b ; J.M. Gatell^b ; ^c ; E. Yuste^b ; I. Haro^a ; ^{isabel.haro@iqac.csic.es" class="auth_mail" title="E-mail the corresponding author}

关键词：Acm ; acetamidomethyl ; ACN ; acetonitrile ; Dbz ; diaminobenzoyl ; DHB ; 2 ; 5-dihydroxybenzoic acid ; DIPEA ; diisopropylethylamine ; FP ; fusion peptide ; GBV-C ; GB virus C ; HAART ; highly active antiretroviral therapy ; HATU ; 2-(1H-7-azabenzotriazole-1-yl)-113 ; 3-tetramethyluronium hexafluorophosphate methanaminium ; HB ; helix bundle ; HT ; head-to-tail ; LUV ; large unilamelar vesicles ; mAb ; monoclonal antibody ; MPAA ; 4-mercaptophenylacetic acid ; MPER ; membrane proximal external region ; NBD ; 6-(7-nitrobenzofur

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2016

5.Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells

作者：Mercedes Bermejo^a ; ¹ ; Marí ; a Rosa Ló ; pez-Huertas^a ; ¹ ; Javier Garcí ; a-Pé ; rez^a ; Nú ; ria Climent^b ; Benjamin Descours^c ; Juan Ambrosioni^d ; Elena Mateos^a ; Sara Rodrí ; guez-Mora^a ; Lucí ; a Rus-Bercial^a ; Monsef Benkirane^c ; José ; M. Miró ; ^d ; Montserrat Plana^b ; José ; Alcamí ; ^a ; Mayte Coiras^a ; ^{mcoiras@isciii.es" class="auth_mail" title="E-mail the corresponding author}

关键词：HIV-1 reservoir ; Dasatinib ; SAMHD1 ; CD4+ T lymphocytes ; Chronic myeloid leukemia

刊名：Biochemical Pharmacology

出版年：2016

6.Modular assembly of dimeric HIV fusion inhibitor peptides with enhanced antiviral potency

作者：Junpeng Xiao ; Thomas J. Tolbert

关键词：HIV ; Peptide ; Dimeric HIV fusion inhibitor ; C37H6 ; CP32M ; Native chemical ligation ; CuAAC

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2013

7.Intranasally administered peptidic viral fusion inhibitor protected hDPP4 transgenic mice from MERS-CoV infection

作者：Prof Shibo Jiang ; MD^a ; ^b ; ^{shibojiang@fudan.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Xinrong Tao ; PhD Dr^c ; Shuai Xia ; BS^a ; Tania Garron ; MS^c ; Fei Yu ; PhD^a ; Lanying Du ; PhD^b ; Prof Lu Lu ; PhD^a ; Dr Chien-Te K Tseng ; PhD^c ; ^{sktseng@utmb.edu" class="auth_mail" title="E-mail the corresponding author}

刊名：The Lancet

出版年：2015

8.Recombinant approach for the production of HIV fusion inhibitor Enfuvirtide using Escherichia coli

作者：Ravikanth Reddy Kosana ; Chitra Bajji ; Radha Madhavi Kanumuri ; Kalpana Panati ; Lakshmi Narasu Mangamoori ; Muralikrishna Reddy Tummuru ; Venkata Ramireddy Narala

关键词：Enfuvirtide ; Fusion protein expression ; Recombinant T20 ; SDS solubilization

刊名：Protein Expression and Purification

出版年：March, 2014

9.ADS-J1 inhibits HIV-1 infection and membrane fusion by targeting the highly conserved pocket in the gp41 NHR-trimer

作者：Fei Yu^a ; ^b ; ^c ; Lu Lu^b ; Qi Liu^b ; Xiaowen Yu^c ; Lili Wang^c ; Elaine He^c ; Peng Zou^c ; Lanying Du^c ; Rogier W. Sanders^d ; ^e ; Shuwen Liu^a ; ^{liusw@smu.edu.cn" class="auth_mail} ; Shibo Jiang^a ; ^b ; ^c ; ^{shibojiang@fudan.edu.cn" class="auth_mail}

关键词：CD ; Circular Dichroism ; CHR ; C-terminal heptad repeat ; Env ; envelope protein ; Fd ; foldon ; HIV-1 ; human immunodeficiency virus 1 ; IC50 ; concentration causing 50% inhibition ; NHR ; N-terminal heptad repeat ; N-PAGE ; native polyacrylamide gel electrophoresis ; PBD ; pocket-binding domain ; 6-HB ; six-helix bundle

刊名：Biochimica et Biophysica Acta (BBA)/Biomembranes

出版年：May, 2014

10.F(ab鈥?₂ fragment of a gp41 NHR-trimer-induced IgM monoclonal antibody neutralizes HIV-1 infection and blocks viral fusion by targeting the conserved gp41 pocket

作者：Lu Lu ; Meili Wei ; Yanxia Chen ; Weiliang Xiong ; Fei Yu ; Zhi Qi ; Shibo Jiang ; Chungen Pan

关键词：HIV-1 ; gp41 ; Monoclonal antibody ; HIV fusion inhibitor ; Immunotherapeutics

刊名：Microbes and Infection

出版年：November, 2013

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