作者：Jesse M. Cedarbaum (1)
Diane Stephenson (2)
Richard Rudick (3)
Maria C. Carrillo (4)
Glenn Stebbins (5)
Douglas Kerr (6)
Jill Heemskerk (7)
Wendy R. Galpern (8)
Petra Kaufmann (9)
David Cella (10)
Maria Isaac (11)
Marc K. Walton (12)

1. Neurology Early Clinical Development ; Biogen Idec ; 14 Cambridge Center ; Cambridge ; MA ; 02142 ; USA
2. Coalition Against Major Diseases ; Critical Path Institute ; Tucson ; AZ ; USA
3. Value Based Medicine ; Biogen Idec ; Cambridge ; MA ; USA
4. Medical & Scientific Relations ; Alzheimer鈥檚 Association ; Chicago ; IL ; USA
5. Department of Neurological Sciences ; Rush University Medical Center ; Chicago ; IL ; USA
6. Clinical and Safety Sciences ; Biogen Idec ; Cambridge ; MA ; USA
7. Division of Adult Translational Research ; National Institute of Mental Health ; National Institutes of Health ; Bethesda ; MD ; USA
8. Office of Clinical Research ; National Institute of Neurological Disorders and Stroke ; Bethesda ; MD ; USA
9. Division of Clinical Innovation ; National Center for Advancing Translational Sciences ; National Institutes of Health ; Bethesda ; MD ; USA
10. Northwestern University Feinberg School of Medicine ; Chicago ; IL ; USA
11. European Medicines Agency ; London ; UK
12. Office of Translational Sciences Center for Drug Evaluation and Research Food and Drug Administration ; Silver Spring ; MD ; USA

关键词：Clinical trials ; Clinical outcome assessments

刊名：Neurotherapeutics

出版年：2015

作者：Anika C. Jahns (1) (2) (4)
Bernd H. A. Rehm (1) (2) (3)

1. Institute of Fundamental Sciences ; Massey University ; Private Bag 11222 ; Palmerston North ; 4442 ; New Zealand
2. PolyBatics Ltd ; BioCommerce Centre ; Dairy Farm Road ; Palmerston North ; 4442 ; New Zealand
4. Department of Medical Biosciences ; Ume氓 University ; 90185 ; Ume氓 ; Sweden
3. MacDiarmid Institute for Advanced Materials and Nanotechnology ; Kelburn Parade ; Wellington ; 6140 ; New Zealand

关键词：Beads ; Lipase ; PHA synthase (PhaC) ; Polyhydroxyalkanoate beads

刊名：Biotechnology Letters

出版年：2015

作者：David J. Irwin (1) (2)
Nigel J. Cairns (4)
Murray Grossman (2)
Corey T. McMillan (2)
Edward B. Lee (3)
Vivianna M. Van Deerlin (1)
Virginia M.-Y. Lee (1)
John Q. Trojanowski (1)

1. Department of Pathology and Laboratory Medicine ; Center for Neurodegenerative Disease Research ; Institute on Ageing ; University of Pennsylvania School of Medicine ; HUP Maloney 3rd Floor ; 36th and Spruce Streets ; Philadelphia ; PA ; 19104-4283 ; USA
2. Department of Neurology ; Penn Frontotemporal Degeneration Center ; University of Pennsylvania ; Philadelphia ; PA ; 19104 ; USA
4. Department of Pathology and Immunology ; Washington University School of Medicine ; St. Louis ; MO ; 63110 ; USA
3. Translational Neuropathology Research Laboratory ; Department of Pathology and Laboratory Medicine ; Perelman School of Medicine ; University of Pennsylvania ; Philadelphia ; PA ; 19104 ; USA

关键词：FTLD ; TDP ; 43 ; Tau ; ALS ; C9orf72 ; GRN ; MAPT

刊名：Acta Neuropathologica

出版年：2015

作者：Thomas M. Bocan (1) (2)
Rekha G. Panchal (1)
Sina Bavari (1)

1. Molecular and Translational Sciences ; US Army Medical Research Institute of Infectious Diseases (USAMRIID) ; 1425 Porter Street ; Ft. Detrick ; MD ; 21702 ; USA
2. The Geneva Foundation ; 917 Pacific Ave ; Suite 600 ; Tacoma ; WA ; 98402 ; USA

关键词：In vivo imaging ; MRI ; PET ; SPECT ; CT ; Optical ; Ultrasound ; BSL3/4 pathogens

刊名：Molecular Imaging and Biology

出版年：2015

作者：Jonas Ecker (1)
Ina Oehme (1)
Ralph Mazitschek (2) (3)
Andrey Korshunov (4) (5)
Marcel Kool (6) (7)
Thomas Hielscher (8)
Judit Kiss (1) (9)
Florian Selt (1) (9)
Carina Konrad (1)
Marco Lodrini (1) (10)
Hedwig E Deubzer (1) (10) (9)
Andreas von Deimling (4) (5)
Andreas E Kulozik (9)
Stefan M Pfister (6) (7) (9)
Olaf Witt (1) (9)
Till Milde (1) (9)

1. Clinical Cooperation Unit Pediatric Oncology (G340) ; German Cancer Research Center (DKFZ) ; Im Neuenheimer Feld 280 ; 69120 ; Heidelberg ; Germany
2. Center for Systems Biology ; Massachusetts General Hospital ; Boston ; MA ; 02114 ; USA
3. The Broad Institute of Harvard and MIT ; Cambridge ; Massachusetts ; 02142 ; USA
4. Department of Neuropathology ; University Hospital Heidelberg ; Im Neuenheimer Feld 224 ; 69120 ; Heidelberg ; Germany
5. Clinical Cooperation Unit Neuropathology (G380) ; German Cancer Research Center (DKFZ) ; and German Cancer Consortium (DKTK) ; Heidelberg ; Germany
6. Division of Pediatric Neurooncology (B062) ; German Cancer Research Center (DKFZ) ; Heidelberg ; Germany ; and German Cancer Consortium (DKTK) ; Heidelberg ; Germany
7. German Cancer Consortium (DKTK) ; Heidelberg ; Germany
8. Division of Biostatistics (C060) ; German Cancer Research Center (DKFZ) ; Heidelberg ; Germany
9. Section of Pediatric Brain Tumors ; Department of Pediatric Oncology ; Hematology and Immunology ; University Hospital Heidelberg ; Im Neuenheimer Feld 430 ; 69120 ; Heidelberg ; Germany
10. Department of Pediatric Hematology ; Oncology and Bone Marrow Transplantation ; Charit茅 - University Medicine Berlin ; CVK ; CC17 ; Augustenburger Platz 1 ; 13353 ; Berlin ; Germany

关键词：Medulloblastoma ; HDAC ; HDAC inhibitor ; HDAC2 ; MYC

刊名：Acta Neuropathologica Communications

出版年：2015

作者：Sarah Leyking (1) (2)
Karin Budich (2)
Kai van Bentum (1) (2)
Stephan Thijssen (2) (4)
Hashim Abdul-Khaliq (3)
Danilo Fliser (1)
Martina Sester (2)
Urban Sester (1)

1. Department of Internal Medicine IV ; Saarland University ; Homburg ; Germany
2. Department of Transplant and Infection Immunology ; Saarland University ; D-66421 ; Homburg ; Germany
4. Current affiliation ; Renal Research Institute ; New York ; USA
3. Department of Paediatric Cardiology ; Saarland University ; Homburg ; Germany

关键词：Circadian rhythm ; T ; cell reactivity ; Flow ; cytometry ; Whole blood assay ; Kidney transplantation ; Calcineurin inhibitor ; Tacrolimus ; Cyclosporine A ; Immunosuppression ; Pharmacokinetics ; Pharmacodynamics

刊名：Journal of Translational Medicine

出版年：2015

作者：Jesse M. Cedarbaum (1)
Diane Stephenson (2)
Richard Rudick (3)
Maria C. Carrillo (4)
Glenn Stebbins (5)
Douglas Kerr (6)
Jill Heemskerk (7)
Wendy R. Galpern (8)
Petra Kaufmann (9)
David Cella (10)
Maria Isaac (11)
Marc K. Walton (12)

1. Neurology Early Clinical Development ; Biogen Idec ; 14 CambridgeCenter ; Cambridge ; MA ; 02142 ; USA
2. Coalition Against Major Diseases ; Critical Path Institute ; Tucson ; AZ ; USA
3. Value Based Medicine ; Biogen Idec ; Cambridge ; MA ; USA
4. Medical & Scientific Relations ; Alzheimer鈥檚 Association ; Chicago ; IL ; USA
5. Department of Neurological Sciences ; Rush University Medical Center ; Chicago ; IL ; USA
6. Clinical and Safety Sciences ; Biogen Idec ; Cambridge ; MA ; USA
7. Division of Adult Translational Research ; National Institute of Mental Health ; National Institutes of Health ; Bethesda ; MD ; USA
8. Office of Clinical Research ; National Institute of Neurological Disorders and Stroke ; Bethesda ; MD ; USA
9. Division of Clinical Innovation ; National Center for Advancing Translational Sciences ; National Institutes of Health ; Bethesda ; MD ; USA
10. Northwestern University Feinberg School of Medicine ; Chicago ; IL ; USA
11. European Medicines Agency ; London ; UK
12. Office of Translational Sciences Center for Drug Evaluation and Research Food and Drug Administration ; Silver Spring ; MD ; USA

刊名：Neurotherapeutics

出版年：2015

作者：Sara Tomei (32) (33) (34)
Davide Bedognetti (32) (34)
Valeria De Giorgi (32)
Michele Sommariva (32) (35)
Sara Civini (36)
Jennifer Reinboth (32) (37) (38)
Muna Al Hashmi (34)
Maria Libera Ascierto (32) (39)
Qiuzhen Liu (32)
Ben D Ayotte (40)
Andrea Worschech (33)
Lorenzo Uccellini (32) (41)
Paolo A Ascierto (42)
David Stroncek (36)
Giuseppe Palmieri (43)
Lotfi Chouchane (33)
Ena Wang (32) (34)
Francesco M Marincola (32) (34)

32. Infectious Disease and Immunogenetics Section (IDIS) ; Department of Transfusion Medicine ; Clinical Center and Trans-NIH Center for Human Immunology (CHI) ; National Institutes of Health ; Bethesda ; Maryland ; USA
33. Department of Genetic Medicine ; Weill Cornell Medical College in Qatar ; PO Box 24144 ; Doha ; Qatar
34. Sidra Medical and Research Center ; P.O. Box 26999 ; Doha ; Qatar
35. Department of Biomedical Sciences for Health ; Universita degli Studi di Milano ; Milan ; Italy
36. Cell Processing Section ; Department of Transfusion Medicine ; Clinical Center and Trans-NIH Center for Human Immunology (CHI) ; National Institutes of Health ; Bethesda ; Maryland ; USA
37. Department of Biochemistry ; Biocenter ; University of Wuerzburg ; Wuerzburg ; 97074 ; Germany
38. Genelux Corporation ; San Diego Science Center ; San Diego ; California ; USA
39. Center of Excellence for Biomedical Research (CEBR) ; University of Genoa ; Kragujevac ; Italy
40. Department of Biology ; Northern Michigan University ; Marquette ; MI ; USA
41. Institute of Infectious and Tropical Diseases ; University of Milan ; L. Sacco Hospital ; Milan ; Italy
42. Istituto Nazionale Tumori Fondazione 鈥淕. Pascale鈥? Via G. Semmola ; Naples ; Italy
43. Institute of Biomolecular Chemistry ; National Research Council ; Sassari ; Italy

刊名：Journal of Translational Medicine

出版年：2015

作者：Rachel S Sealfon (1) (2)
Michael F Lin (3)
Irwin Jungreis (1) (2)
Maxim Y Wolf (1) (2)
Manolis Kellis (1) (2)
Pardis C Sabeti (2) (4)

1. MIT ; Computer Science and Artificial Intelligence Laboratory ; Cambridge ; MA ; 02139 ; USA
2. Broad Institute ; Cambridge ; MA ; 02142 ; USA
3. DNANexus ; Mountain View ; CA ; 94040 ; USA
4. Department of Organismic and Evolutionary Biology ; Harvard University ; Cambridge ; MA ; 02138 ; USA

刊名：Genome Biology

出版年：2015

作者：Jaladhi Nayak (1)
Adam J Gastonguay (1)
Marat R Talipov (2)
Padmanabhan Vakeel (1)
Elise A Span (4)
Kelsey S Kalous (4)
Raman G Kutty (1)
Davin R Jensen (3)
Phani Raj Pokkuluri (5)
Daniel S Sem (4)
Rajendra Rathore (2)
Ramani Ramchandran (1) (6)

1. Department of Pediatrics ; Medical College of Wisconsin ; CRI Developmental Vascular Biology Program ; P.O. Box 26509 ; C3420 ; 8701 Watertown Plank Road ; Milwaukee ; WI ; 53226 ; USA
2. Department of Chemistry ; Marquette University ; Wehr Chemistry Building ; P.O. Box 1881 ; 535聽N. 14th Street ; Milwaukee ; WI ; 53201 ; USA
4. Center for Structure-based Drug Design and Development ; Department of Pharmaceutical Sciences ; Concordia University of Wisconsin ; Mequon ; WI ; 53097 ; USA
3. Department of Biochemistry ; Medical College of Wisconsin ; Children鈥檚 Research Institute (CRI) Developmental Vascular Biology Program ; Translational and Biomedical Research Center ; 8701 Watertown Plank Road ; P.O. Box 26509 ; Milwaukee ; WI ; 53226 ; USA
5. Biosciences Division ; Argonne National Laboratory ; 9700聽S. Cass Avenue Lemont ; Argonne ; IL ; 60439 ; USA
6. Department of Obstetrics and Gynecology ; CRI Developmental Vascular Biology Program ; P.O. Box 26509 ; C3420 ; 8701 Watertown Plank Road ; Milwaukee ; WI ; 53226 ; USA

关键词：DUSP5 ; Mutation ; Vascular anomalies ; Protein purification ; Molecular modeling

刊名：BMC Biochemistry

出版年：2014