作者：David Buchbinder (1) (12)
Rebecca Baker (2)
Yu Nee Lee (3)
Juan Ravell (2)
Yu Zhang (4)
Joshua McElwee (5)
Diane Nugent (1)
Emily M. Coonrod (7)
Jacob D. Durtschi (7)
Nancy H. Augustine (7) (8)
Karl V. Voelkerding (7) (8)
Krisztian Csomos (11)
Lindsey Rosen (2)
Sarah Browne (2)
Jolan E. Walter (11) (6)
Luigi D. Notarangelo (6)
Harry R. Hill (10) (7) (8) (9)
Attila Kum谩novics (7) (8)

1. Pediatrics / Hematology ; CHOC Children鈥檚 Hospital鈥擴C Irvine ; Orange ; CA ; USA
12. Division of Hematology ; CHOC Children鈥檚 Hospital ; 1201 La Veta ; Orange ; CA ; 92868 ; USA
2. Laboratory of Clinical Infectious Diseases ; NIAID ; NIH ; Bethesda ; MD ; USA
3. Division of Immunology ; Boston Children鈥檚 Hospital Harvard Medical School ; Boston ; MA ; USA
4. Laboratory of Host Defenses ; National Institutes of Allergy and Infectious Diseases ; NIH ; Bethesda ; MD ; USA
5. Merck Research Laboratories ; Merck & Co. Inc. ; Boston ; MA ; USA
7. ARUP Institute for Clinical and Experimental Pathology ; Salt Lake City ; UT ; USA
8. Department of Pathology ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA
11. Pediatric Allergy & Immunology and the Center for Immunology and Inflammatory Diseases ; Massachusetts General Hospital ; Harvard Medical School ; Boston ; MA ; USA
6. Division of Immunology ; Boston Children鈥檚 Hospital ; Boston ; MA ; USA
10. Department of Pediatrics ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA
9. Department of Internal Medicine ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA

关键词：RAG1 ; RAG deficiency ; primary immunodeficiency ; severe combined immune deficiency ; common variable immunodeficiency disorder ; exome sequencing ; gene panel

刊名：Journal of Clinical Immunology

出版年：2015

作者：Birgit Rathkolb (1) (2)
Martina Klempt (1)
Sibylle Sabrautzki (2) (6)
Dian Michel (2) (6)
Matthias Klaften (2) (6)
J眉rgen Laufs (3)
Reinhard Sedlmeier (3)
Wolfgang Hans (2) (6)
Helmut Fuchs (2) (6)
Martina U. Muckenthaler (4)
Marion Horsch (2) (6)
Dean R. Campagna (5)
Mark Fleming (5)
Martin Hrab茅 de Angelis (2) (6) (7)
Eckhard Wolf (1)
Bernhard Aigner (1)

1. Chair for Molecular Animal Breeding and Biotechnology ; Department of Veterinary Sciences ; and Laboratory for Functional Genome Analysis (LAFUGA) ; Gene Center ; LMU Munich ; Feodor-Lynen-Str. 25 ; 81377 ; Munich ; Germany
2. Institute of Experimental Genetics ; Helmholtz Zentrum M眉nchen ; German Research Center for Environmental Health ; Neuherberg ; TU Munich ; Freising-Weihenstephan ; Germany
6. Chair for Experimental Genetics ; TU Munich ; Freising-Weihenstephan ; Germany
3. Ingenium Pharmaceuticals ; Martinsried ; Germany
4. Department of Paediatric Oncology ; Hematology and Immunology ; University of Heidelberg ; Heidelberg ; Germany
5. Department of Pathology ; Boston Children鈥檚 Hospital ; Boston ; MA ; USA
7. German Center for Diabetes Research ; Neuherberg ; Germany

关键词：Iron ; Ferritin ; Transferrin ; Mouse ; ENU ; Mutagenesis ; Hyperferritinemia

刊名：Biometals

出版年：2015

作者：Federico Comoglio (1)
Cem Sievers (1) (2) (3)
Renato Paro (1) (4)

1. Department of Biosystems Science and Engineering ; Swiss Federal Institute of Technology Zurich ; Mattenstrasse 26 ; Basel ; 4058 ; Switzerland
2. Department of Pathology and Center for Cancer Research ; Massachusetts General Hospital and Harvard Medical School ; Boston ; USA
3. Broad Institute of MIT and Harvard ; Cambridge ; USA
4. Faculty of Science ; University of Basel ; Klingelbergstrasse 504056 ; Basel ; Switzerland

关键词：PAR ; CLIP ; RNA ; RNA binding proteins ; Bayesian statistics

刊名：BMC Bioinformatics

出版年：2015

作者：Hyong Woo Choi (1) (2)
Byung Kook Hwang (1)

1. Laboratory of Molecular Plant Pathology ; College of Life Sciences and Biotechnology ; Korea University ; Anam-dong ; Sungbuk-ku ; Seoul ; 136-713 ; Republic of Korea
2. Boyce Thompson Institute for Plant Research ; Tower Road ; Ithaca ; NY ; 14853-1801 ; USA

关键词：Capsicum annuum ; Hypersensitive cell death ; Defense ; Cell death gene ; Disease resistance ; Disease ; associated cell death

刊名：Planta

出版年：2015

作者：Ammad Ahmad Farooqi (1)
Fazlul H Sarkar (2)

1. Laboratory for Translational Oncology and Personalized Medicine ; Rashid Latif Medical College ; 35 Km Ferozepur Road ; Lahore ; Pakistan
2. Departments of Pathology and Oncology ; Karmanos Cancer Institute ; Wayne State University School of Medicine ; 740 HWCRC ; 4100 JohnR Street ; Detroit ; MI ; 48201 ; USA

关键词：Prostate cancer ; Intracellular signaling ; Apoptosis

刊名：Cancer Cell International

出版年：2015

作者：Francesco Abate (1) (2) (3)
Sakellarios Zairis (2)
Elisa Ficarra (3)
Andrea Acquaviva (3)
Chris H Wiggins (2) (6) (7)
Veronique Frattini (5)
Anna Lasorella (5)
Antonio Iavarone (5)
Giorgio Inghirami (4)
Raul Rabadan (1) (2)

1. Department of Biomedical Informatics ; Columbia University ; 1130 St. Nicholas Ave ; New York ; NY ; 10032 ; USA
2. Center for Computational Biology and Bioinformatics ; Columbia University ; 1130 St. Nicholas Ave ; New York ; NY ; 10032 ; USA
3. Department of Control and Computer Engineering ; Politecnico di Torino ; Torino ; 10129 ; Italy
6. Department of Applied Physics and Applied Mathematics ; The Fu Foundation School for Engineering and Applied Sciences ; Columbia University ; 500 W. 120th Street ; Mudd 200 ; MC 4701 ; New York ; New York ; 10027 ; USA
7. Institute for Data Sciences and Engineering ; Columbia University ; 500 W. 120th Street ; Mudd 524 ; New York ; New York ; 10027 ; USA
5. Institute for Cancer Genetics ; Columbia University Medical Center ; New York ; New York ; USA
4. Department of Pathology ; Center for Experimental Research and Medical Studies ; Laboratory of Functional Genomics ; University of Torino ; Torino ; Italy

关键词：Gene fusion ; Next ; generation sequencing ; Machine learning

刊名：BMC Systems Biology

出版年：2014

作者：Timothy H Ciesielski (1) (2)
Sarah A Pendergrass (3) (4)
Marquitta J White (1) (2) (5)
Nuri Kodaman (1) (2) (5)
Rafal S Sobota (1) (2) (5)
Minjun Huang (1)
Jacquelaine Bartlett (2)
Jing Li (1)
Qinxin Pan (1)
Jiang Gui (2) (6)
Scott B Selleck (4)
Christopher I Amos (2) (6)
Marylyn D Ritchie (3) (4)
Jason H Moore (1) (2) (6)
Scott M Williams (1) (2)

1. Department of Genetics ; Geisel School of Medicine at Dartmouth ; Hanover ; NH ; 03755 ; USA
2. Institute for Quantitative Biomedical Sciences ; Dartmouth College ; Hanover ; NH ; 03755 ; USA
3. Center for Systems Genomics ; Pennsylvania State University ; University Park ; PA ; 16802 ; USA
4. Department of Biochemistry & Molecular Biology ; Pennsylvania State University ; University Park ; PA ; 16802 ; USA
5. Center for Human Genetics Research ; Vanderbilt University ; Nashville ; TN ; 37232-0700 ; USA
6. Community and Family Medicine ; Section of Biostatistics & Epidemiology ; Geisel School of Medicine ; Hanover ; NH ; 03766 ; USA

关键词：Replication ; Validation ; Complex disease ; Heterogeneity ; GWAS ; Omics ; Type 2 error ; Type 1 error ; False negatives ; False positives

刊名：BioData Mining

出版年：2014

作者：John E Greenlee (1) (2) (3)
Susan A Clawson (1) (2)
Kenneth E Hill (1) (2)
Blair Wood (1) (2)
Stacey L Clardy (1) (2)
Ikuo Tsunoda (4)
Troy D Jaskowski (5)
Noel G Carlson (2) (3) (6) (7) (8)

1. Neurology Service ; George E. Wahlen Veterans Affairs Medical Center ; 500 Foothill Drive ; Salt Lake City ; UT ; 84148 ; USA
2. Department of Neurology ; University of Utah School of Medicine ; 50 North Medical Drive ; Salt Lake City ; UT ; 84132 ; USA
3. Brain Institute ; University of Utah ; 383 Colorow Drive ; Salt Lake City ; UT ; 84108 ; USA
4. Department of Microbiology and Immunology ; Louisiana State University Health Science Center ; 1501 Kings Highway ; Shreveport ; LA ; 71130 ; USA
5. Institute for Clinical and Experimental Pathology ; ARUP ; 500 Chipeta Way ; Salt Lake City ; UT ; 84108 ; USA
6. GRECC ; George E. Wahlen Veterans Affairs Medical Center ; 500 Foothill Drive ; Salt Lake City ; UT ; 84148 ; USA
7. Department of Neurobiology and Anatomy ; University of Utah School of Medicine ; 50 North Medical Drive ; Salt Lake City ; UT ; 84132 ; USA
8. Center on Aging ; University of Utah ; 10 South 2000 East ; Salt Lake City ; UT ; 84112-5880 ; USA

关键词：Paraneoplastic syndromes ; Anti ; Hu antibody ; Anti ; Ri antibody ; Neurons ; Brain slice cultures ; Organotypic brain cultures ; Cell death ; Apoptosis ; Hu antigens ANNA1 ; ANNA2

刊名：Journal of Neuroinflammation

出版年：2014

作者：Xin Qi (1) (2)
Daihou Wang (2) (3)
Ivan Rodero (3)
Javier Diaz-Montes (3)
Rebekah H Gensure (1)
Fuyong Xing (5)
Hua Zhong (1)
Lauri Goodell (1)
Manish Parashar (3)
David J Foran (1) (2) (4)
Lin Yang (5)

1. Department of Pathology and Laboratory Medicine ; Rutger Robert Wood Johnson Medical School ; 675 Hoes Lane ; Piscataway ; NJ ; USA
2. Center for Biomedical Imaging and Informatics ; Rutgers Cancer Institute of New Jersey ; New Brunswick ; NJ ; USA
3. Rutgers Discovery Informatics Institute and NSF Cloud and Autonomic Computing Center ; Department of Electrical and Computer Engineering ; Rutgers University ; Piscataway ; NJ ; USA
5. Division of Biomedical Informatics ; Department of Biostatistics ; Department of Computer Science ; University of Kentucky ; Lexington ; KY ; USA
4. Department of Radiology ; Rutgers - Robert Wood Johnson Medical School ; Piscataway ; NJ ; USA

关键词：Histopathology ; Digital pathology ; Content ; based image retrieval ; High performance computing

刊名：BMC Bioinformatics

出版年：2014

作者：Yunshan Wang (6) (7)
Pengju Zhang (8)
Ziming Liu (9)
Qin Wang (10)
Mingxin Wen (6)
Yuli Wang (6)
Hongtu Yuan (11)
Jian-Hua Mao (12)
Guangwei Wei (6)

6. Department of Anatomy and Key Laboratory of Experimental Teratology ; Ministry of Education ; Shandong University School of Medicine ; 44 Wenhua Xi Road ; Jinan ; Shandong ; 250012 ; P.R. China
7. Department of International Biotechnology R&D Center ; Shandong University School of Ocean ; 180 Wenhua Xi Road ; Weihai ; Shandong ; 264209 ; P.R. China
8. Department of Biochemistry and Molecular Biology ; Shandong University School of Medicine ; 44 Wenhua Xi Road ; Jinan ; Shandong ; 250012 ; P.R. China
9. Department of Neurosurgery ; The Fifth People鈥檚 Hospital ; 447 Jingshen Road ; Jinan ; 250022 ; P.R. China
10. Department of Anesthesiology ; Qilu Hospital ; Shandong University ; 107 Wenhua Xi Road ; Jinan ; 250012 ; P.R. China
11. Department of Pathology ; Shandong Cancer Hospital and Institute ; Jinan ; 250012 ; P.R. China
12. Life Sciences Division ; Lawrence Berkeley National Laboratory ; Berkeley ; CA ; 94127 ; USA

关键词：CUL4A ; Lung cancer ; EGFR ; Erlotinib

刊名：Molecular Cancer

出版年：2014