作者：Ingrid Slade (1) (2) (3)
Daniel Riddell (1)
Clare Turnbull (1) (4)
Helen Hanson (1) (4)
Nazneen Rahman (1) (4)
for the MCG programme

1. The Institute of Cancer Research ; 15 Cotswold Road ; Sutton ; Surrey ; SM2 5NG ; UK
2. The Ethox Centre ; Nuffield Department of Population Health ; University of Oxford ; Old Road Campus ; Oxford ; OX3 7LF ; UK
3. Centre for Personalised Medicine ; Wellcome Trust Centre for Human Genetics ; St Anne鈥檚 College ; University of Oxford ; Oxford ; OX2 6HS ; UK
4. Royal Marsden NHS Foundation Trust ; Downs Road ; Sutton ; Surrey ; SM2 5PT ; UK

刊名：Genome Medicine

出版年：2015

作者：Jonny Coppel (1)
Philip Hennis (1)
Edward Gilbert-Kawai (1)
Michael PW Grocott (1) (2) (3) (4)

1. University College London Centre for Altitude Space and Extreme Environment Medicine ; UCLH NIHR Biomedical Research Centre ; Institute of Sport and Exercise Health ; 170 Tottenham Court Road ; London ; W1T 7HA ; UK
2. Integrative Physiology and Critical Illness Group ; Clinical and Experimental Sciences ; Mailpoint 810 ; Sir Henry Wellcome Laboratories ; Faculty of Medicine ; University of Southampton ; University Hospital Southampton NHS Foundation Trust ; Tremona Road ; Southampton ; SO16 6YD ; UK
3. Anaesthesia and Critical Care Research Unit ; University Hospital Southampton NHS Foundation Trust ; Mailpoint 27 ; D Level ; Centre Block ; Tremona Road ; Southampton ; SO16 6YD ; UK
4. NIHR Southampton Respiratory Biomedical Research Unit ; Southampton ; SO16 5ST ; UK

关键词：Normobaric hypoxia ; Hypobaric hypoxia ; Altitude

刊名：Extreme Physiology & Medicine

出版年：2015

作者：Paul Charlesworth (1) (2)
Ellese Cotterill (3)
Andrew Morton (1) (4)
Seth GN Grant (5)
Stephen J Eglen (3)

1. Genes to Cognition Programme ; Wellcome Trust Sanger Institute ; Genome Campus ; CB10 1SA ; Hinxton ; UK
2. Current address ; Department of Physiology ; Development and Neuroscience ; Physiological Laboratory ; Downing Street ; Cambridge ; CB2 3EG ; UK
3. Cambridge Computational Biology Institute ; University of Cambridge ; Wilberforce Road ; Cambridge ; CB3 0WA ; UK
4. Current address ; Centre for Integrative Physiology ; University of Edinburgh School of Biomedical Sciences ; EH8 9XD ; Edinburgh ; UK
5. Centre for Clinical Brain Sciences and Centre for Neuroregeneration ; Chancellors Building ; Edinburgh University ; 49 Little France Crescent ; Edinburgh ; EH16 4SB ; UK

关键词：Multielectrode array ; Spontaneous activity ; Cortex ; Hippocampus ; Principal component analysis ; Support vector machine ; Classification tree

刊名：Neural Development

出版年：2015

作者：Jette Bork-Jensen (1) (2)
Camilla Scheele (3)
Daniel V. Christophersen (1) (4)
Emma Nilsson (1)
Martin Friedrichsen (1) (2) (5)
Denise S. Fernandez-Twinn (6)
Louise G. Grunnet (2)
Thomas Litman (7)
Kim Holmstr酶m (8)
Birgitte Vind (9)
Kurt H酶jlund (9)
Henning Beck-Nielsen (9)
J酶rgen Wojtaszewski (5)
Susan E. Ozanne (6)
Bente K. Pedersen (3)
Pernille Poulsen (1) (4)
Allan Vaag (1) (2)

1. Steno Diabetes Center ; Gentofte ; Denmark
2. Department of Endocrinology (Diabetes and Metabolism) ; Rigshospitalet ; sec. 7652 ; Tagensvej 20 ; DK-2200 ; Copenhagen N ; Denmark
3. Centre of Inflammation and Metabolism ; Faculty of Health Sciences ; University of Copenhagen ; Copenhagen ; Denmark
4. Novo Nordisk ; Bagsv忙rd ; Denmark
5. Department of Exercise and Sport Sciences ; University of Copenhagen ; Copenhagen ; Denmark
6. University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit ; Wellcome Trust-Institute of Metabolic Science ; Addenbrooke鈥檚 Treatment Centre ; Addenbrooke鈥檚 Hospital ; Cambridge ; UK
7. Molecular Biomedicine ; LEO Pharma ; Ballerup ; Denmark
8. Bioneer ; H酶rsholm ; Denmark
9. Odense University Hospital ; Odense ; Denmark

关键词：Insulin signalling ; Low birthweight ; MicroRNA ; miR ; 15b ; miR ; 16 ; Muscle ; Twins ; Type 2 diabetes

刊名：Diabetologia

出版年：2015

作者：Nicole Gossan (1)
Ray Boot-Handford (2)
Qing-Jun Meng (1)

1. Faculty of Life Sciences ; University of Manchester ; A.V. Hill Building ; Oxford Road ; Manchester ; M13 9PT ; UK
2. Wellcome Trust Centre for Cell Matrix Research ; University of Manchester ; Oxford Road ; Manchester ; M13 9PT ; UK

关键词：Osteoarthritis ; Ageing ; Circadian clock ; Chondrocytes ; Extracellular matrix

刊名：Biogerontology

出版年：2015

作者：Benjamin Lehne (1)
Alexander W Drong (2)
Marie Loh (1) (3)
Weihua Zhang (1) (4)
William R Scott (1) (5)
Sian-Tsung Tan (4) (5)
Uzma Afzal (1) (4)
James Scott (5)
Marjo-Riitta Jarvelin (1) (3) (6) (7) (8) (9)
Paul Elliott (1) (9)
Mark I McCarthy (10) (2)
Jaspal S Kooner (11) (4) (5)
John C Chambers (1) (11) (4)

1. Department of Epidemiology and Biostatistics ; Imperial College London ; London ; W2 1PG ; UK
2. Wellcome Trust Centre for Human Genetics ; University of Oxford ; Oxford ; UK
3. Institute of Health Sciences ; University of Oulu ; P.O. Box 5000 ; Oulu ; FI-90014 ; Finland
4. Ealing Hospital NHS Trust ; Middlesex ; UB1 3HW ; UK
5. National Heart and Lung Institute ; Imperial College London ; London ; W12 0NN ; UK
6. Biocenter Oulu ; University of Oulu ; P.O. Box 5000 ; Aapistie 5A ; Oulu ; FI-90014 ; Finland
7. Unit of Primary Care ; Oulu University Hospital ; Kajaanintie 50 ; P.O. Box 20 ; FI-90220 ; Oulu ; 90029 OYS ; Finland
8. Department of Children and Young People and Families ; National Institute for Health and Welfare ; Aapistie 1 ; Box 310 ; Oulu ; FI-90101 ; Finland
9. MRC-PHE Centre for Environment and Health ; School of Public Health ; Imperial College London ; London ; W2 1PG ; UK
10. Oxford Centre for Diabetes Endocrinology and Metabolism ; University of Oxford ; Oxford ; UK
11. Imperial College Healthcare NHS Trust ; London ; W12 0HS ; UK

刊名：Genome Biology

出版年：2015

作者：Piero Poletti (1) (2)
Stefano Merler (2)
Marco Ajelli (2)
Piero Manfredi (3)
Patrick K Munywoki (4)
D James Nokes (4) (5)
Alessia Melegaro (1)

1. Dondena Centre for Research on Social Dynamics and Public Policy ; Department of Policy Analysis and Public Management ; Universit谩 Commerciale L. Bocconi ; via Rontgen n. 1 ; Milan ; Italy
2. Center for Information Technology ; Bruno Kessler Foundation ; via Sommarive ; 18 ; Trento ; Italy
3. Department of Statistics and Mathematics Applied to Economics ; University of Pisa ; via Ridolfi 10 ; Pisa ; Italy
4. Kenyan Medical Research Institute (KEMRI) - Wellcome Trust Research Programme ; Centre for Geographic Medicine Research (Coast) ; Hospital Road ; Kilifi ; Kenya
5. School of Life Sciences and WIDER ; University of Warwick ; Coventry CV4 7AL ; Warwick ; UK

关键词：Computational models ; Infectious diseases ; RSV ; Vaccination ; Household transmission

刊名：BMC Medicine

出版年：2015

作者：Daniela Moralli (1)
Zoia L. Monaco (2)

1. The Wellcome Trust Centre for Human Genetics ; University of Oxford ; Roosevelt Drive ; Oxford ; OX3 7BN ; UK
2. Department of Biomedical Engineering ; Tufts University ; 4 Colby Street ; 02155-6013 ; Medford ; MA ; USA

关键词：gene therapy ; gene expression ; viral replication ; viral vector

刊名：Chromosome Research

出版年：2015

作者：Isidro Cortes-Ciriano (1)
Daniel S Murrell (2)
Gerard JP van Westen (3)
Andreas Bender (2)
Th茅r猫se E Malliavin (1)

1. D茅partement de Biologie Structurale et Chimie ; Institut Pasteur ; Unit茅 de Bioinformatique Structurale ; CNRS UMR 3825 ; 25 ; rue du Dr Roux ; Paris ; 75015 ; France
2. Centre for Molecular Science Informatics ; Department of Chemistry ; University of Cambridge ; Cambridge ; UK
3. European Molecular Biology Laboratory European Bioinformatics Institute Wellcome Trust Genome Campus ; Hinxton ; Cambridge ; CB10 1SD ; UK

关键词：Proteochemometrics ; Cyclooxygenases ; Chemogenomics ; QSAR ; Ensemble modeling ; Applicability domain

刊名：Journal of Cheminformatics

出版年：2015

作者：Colin G Stirrat (27) (28)
Shirjel Alam (27) (28)
Thomas J MacGillivray (27) (29)
Calum D Gray (27) (29)
Marc R Dweck (27) (28)
Saeed Mirsadraee (27) (30)
Graham McKillop (30)
Peter A Henriksen (27) (28)
David Newby (27) (28)
Scott Semple (27) (28)

27. Clinical Research Imaging Centre ; University of Edinburgh ; Edinburgh ; UK
28. Centre for Cardiovascular Science ; University of Edinburgh ; Edinburgh ; UK
29. Wellcome Trust Clinical Research Facility ; NHS Lothian ; Edinburgh ; UK
30. Department of Radiology ; NHS Lothian ; Edinburgh ; UK

刊名：Journal of Cardiovascular Magnetic Resonance

出版年：2015