作者：Jesse M. Cedarbaum (1)
Diane Stephenson (2)
Richard Rudick (3)
Maria C. Carrillo (4)
Glenn Stebbins (5)
Douglas Kerr (6)
Jill Heemskerk (7)
Wendy R. Galpern (8)
Petra Kaufmann (9)
David Cella (10)
Maria Isaac (11)
Marc K. Walton (12)

1. Neurology Early Clinical Development ; Biogen Idec ; 14 Cambridge Center ; Cambridge ; MA ; 02142 ; USA
2. Coalition Against Major Diseases ; Critical Path Institute ; Tucson ; AZ ; USA
3. Value Based Medicine ; Biogen Idec ; Cambridge ; MA ; USA
4. Medical & Scientific Relations ; Alzheimer鈥檚 Association ; Chicago ; IL ; USA
5. Department of Neurological Sciences ; Rush University Medical Center ; Chicago ; IL ; USA
6. Clinical and Safety Sciences ; Biogen Idec ; Cambridge ; MA ; USA
7. Division of Adult Translational Research ; National Institute of Mental Health ; National Institutes of Health ; Bethesda ; MD ; USA
8. Office of Clinical Research ; National Institute of Neurological Disorders and Stroke ; Bethesda ; MD ; USA
9. Division of Clinical Innovation ; National Center for Advancing Translational Sciences ; National Institutes of Health ; Bethesda ; MD ; USA
10. Northwestern University Feinberg School of Medicine ; Chicago ; IL ; USA
11. European Medicines Agency ; London ; UK
12. Office of Translational Sciences Center for Drug Evaluation and Research Food and Drug Administration ; Silver Spring ; MD ; USA

关键词：Clinical trials ; Clinical outcome assessments

刊名：Neurotherapeutics

出版年：2015

作者： Yoshito Hirata ; Kai Morino ; Taiji Suzuki ; Qian Guo…

关键词：mathematical medicine ; dynamical model ; parameter estimation

刊名：Quantitative Biology

出版年：2016

作者：Philip Zeitler (1)
Hubert S. Chou (2)
Kenneth C. Copeland (3)
Mitchell Geffner (4)

1. Department of Pediatrics ; Children鈥檚 Hospital Colorado ; University of Colorado School of Medicine ; 13123 E 16th Avenue ; Aurora ; CO ; USA
2. Clinical Development ; Daiichi Sankyo Pharma Development ; 399 Thornall Street ; Edison ; NJ ; 08837 ; USA
3. Department of Pediatrics ; University of Oklahoma College of Medicine ; 1200 N. Children鈥檚 Ave ; Suite 4500 ; Oklahoma City ; OK ; 73104 ; USA
4. Department of Pediatrics ; Children鈥檚 Hospital of Los Angeles ; University of Southern California School of Medicine ; 4650 Sunset Blvd. ; MS #61 ; Los Angeles ; CA ; 90027 ; USA

关键词：Type 2 diabetes ; Adolescents ; Oral antihyperglycemic agents ; Pediatric diabetes ; TODAY ; Clinical trials

刊名：Current Diabetes Reports

出版年：2015

作者：David Buchbinder (1) (12)
Rebecca Baker (2)
Yu Nee Lee (3)
Juan Ravell (2)
Yu Zhang (4)
Joshua McElwee (5)
Diane Nugent (1)
Emily M. Coonrod (7)
Jacob D. Durtschi (7)
Nancy H. Augustine (7) (8)
Karl V. Voelkerding (7) (8)
Krisztian Csomos (11)
Lindsey Rosen (2)
Sarah Browne (2)
Jolan E. Walter (11) (6)
Luigi D. Notarangelo (6)
Harry R. Hill (10) (7) (8) (9)
Attila Kum谩novics (7) (8)

1. Pediatrics / Hematology ; CHOC Children鈥檚 Hospital鈥擴C Irvine ; Orange ; CA ; USA
12. Division of Hematology ; CHOC Children鈥檚 Hospital ; 1201 La Veta ; Orange ; CA ; 92868 ; USA
2. Laboratory of Clinical Infectious Diseases ; NIAID ; NIH ; Bethesda ; MD ; USA
3. Division of Immunology ; Boston Children鈥檚 Hospital Harvard Medical School ; Boston ; MA ; USA
4. Laboratory of Host Defenses ; National Institutes of Allergy and Infectious Diseases ; NIH ; Bethesda ; MD ; USA
5. Merck Research Laboratories ; Merck & Co. Inc. ; Boston ; MA ; USA
7. ARUP Institute for Clinical and Experimental Pathology ; Salt Lake City ; UT ; USA
8. Department of Pathology ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA
11. Pediatric Allergy & Immunology and the Center for Immunology and Inflammatory Diseases ; Massachusetts General Hospital ; Harvard Medical School ; Boston ; MA ; USA
6. Division of Immunology ; Boston Children鈥檚 Hospital ; Boston ; MA ; USA
10. Department of Pediatrics ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA
9. Department of Internal Medicine ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA

关键词：RAG1 ; RAG deficiency ; primary immunodeficiency ; severe combined immune deficiency ; common variable immunodeficiency disorder ; exome sequencing ; gene panel

刊名：Journal of Clinical Immunology

出版年：2015

作者：Bonnie Kaul Nastasi (1)
Jean J. Schensul (2)
Stephen L. Schensul (3)
Abelwahed Mekki-Berrada (4)
Pertti J. Pelto (8)
Shubhada Maitra (5)
Ravi Verma (6)
Niranjan Saggurti (7)

1. Department of Psychology ; Tulane University ; 2007 Percival Stern Hall ; 6400 Freret Street ; New Orleans ; LA ; 70130 ; USA
2. Institute for Community Research ; Hartford ; CT ; USA
3. University of Connecticut School of Medicine ; Farmington ; CT ; USA
4. Universite Laval ; Quebec ; QC ; Canada
8. University of Connecticut ; Storrs ; CT ; USA
5. Tata Institute of Social Sciences ; Mumbai ; India
6. International Center for Research on Women ; New Delhi ; India
7. Population Council ; New Delhi ; India

关键词：Cultural construction ; Clinical practice ; HIV/STI prevention ; Evidence ; based practice ; Narrative intervention model

刊名：Culture, Medicine and Psychiatry

出版年：2015

作者：Ronald Boellaard (1)
Roberto Delgado-Bolton (2)
Wim J. G. Oyen (3)
Francesco Giammarile (4)
Klaus Tatsch (5)
Wolfgang Eschner (6)
Fred J. Verzijlbergen (7)
Sally F. Barrington (8)
Lucy C. Pike (8)
Wolfgang A. Weber (9)
Sigrid Stroobants (10)
Dominique Delbeke (11)
Kevin J. Donohoe (12)
Scott Holbrook (13)
Michael M. Graham (14)
Giorgio Testanera (15)
Otto S. Hoekstra (1)
Josee Zijlstra (16)
Eric Visser (3)
Corneline J. Hoekstra (17)
Jan Pruim (18)
Antoon Willemsen (18)
Bertjan Arends (19)
J枚rg Kotzerke (20)
Andreas Bockisch (21)
Thomas Beyer (22)
Arturo Chiti (15)
Bernd J. Krause (23)

1. Department of Radiology & Nuclear Medicine ; VU University Medical Centre ; De Boelelaan 1117 ; 1081 HV ; Amsterdam ; The Netherlands
2. Department of Diagnostic Imaging (Radiology) and Nuclear Medicine ; San Pedro Hospital and Centre for Biomedical Research of La Rioja (CIBIR) ; University of La Rioja ; Logro帽o ; La Rioja ; Spain
3. Department of Radiology & Nuclear Medicine ; Radboud University Nijmegen Medical Centre ; Nijmegen ; The Netherlands
4. Department of Nuclear Medicine ; Centre Hospitalier Universitaire de Lyon ; Lyon ; France
5. Department of Nuclear Medicine ; Municipal Hospital Karlsruhe Inc. ; Karlsruhe ; Germany
6. Department of Nuclear Medicine ; University of Cologne ; Cologne ; Germany
7. Department of Nuclear Medicine ; Erasmus Medical Center ; Rotterdam ; The Netherlands
8. PET Imaging Centre ; St Thomas鈥?Hospital ; Division of Imaging Sciences and Biomedical Engineering ; King鈥檚 College London ; King鈥檚 Health Partners ; London ; UK
9. Department of Radiology ; Memorial Sloan Kettering Center ; New York ; NY ; USA
10. Department of Nuclear Medicine ; Antwerp University Hospital ; Antwerp ; Belgium
11. Department of Radiology and Radiological Sciences ; Vanderbilt University Medical Center ; Nashville ; TN ; USA
12. Beth Israel Deaconess Medical Center ; Boston ; MA ; USA
13. Invivo Molecular Imaging LLC ; Gray ; TN ; USA
14. Department of Radiology ; University of Iowa ; Iowa City ; IA ; USA
15. Department of Nuclear Medicine ; Humanitas Clinical and Research Center ; Rozzano ; MI ; Italy
16. Department of Hematology ; VU University Medical Centre ; Amsterdam ; The Netherlands
17. Department of Nuclear Medicine ; Jeroen Bosch Hospital ; Den Bosch ; The Netherlands
18. Department of Nuclear Medicine & Molecular Imaging ; University Medical Centre Groningen ; Groningen ; The Netherlands
19. Department of Clinical Physics ; Catharina Hospital ; Eindhoven ; The Netherlands
20. Clinic and Outpatient Clinic for Nuclear Medicine ; University Hospital Dresden ; Dresden ; Germany
21. Clinic for Nuclear Medicine ; University Hospital Essen ; Essen ; Germany
22. Centre for Medical Physics and Biomedical Engineering ; Medical University of Vienna ; Vienna ; Austria
23. Department of Nuclear Medicine ; University Hospital Rostock ; Rostock ; Germany

关键词：FDG ; PET/CT ; Imaging procedure ; Tumour ; Oncology ; Quantification

刊名：European Journal of Nuclear Medicine and Molecular Imaging

出版年：2015

作者：Whitney L. Stoppel (1)
Chiara E. Ghezzi (1)
Stephanie L. McNamara (1) (2) (3)
Lauren D. Black III (1) (2)
David L. Kaplan (1)

1. Department of Biomedical Engineering ; Tufts University ; Medford ; MA ; 02155 ; USA
2. Cellular ; Molecular and Developmental Biology Program ; Sackler School of Graduate Biomedical Sciences ; Tufts University School of Medicine ; Boston ; MA ; 02111 ; USA
3. The Harvard/MIT MD-PhD Program ; Harvard Medical School ; Boston ; MA ; 02115 ; USA

关键词：Biopolymers ; Scaffolds ; Regenerative medicine

刊名：Annals of Biomedical Engineering

出版年：2015

作者：Matthias Samwald (1)
Jose Antonio Mi帽arro Gim茅nez (1) (2)
Richard D Boyce (3)
Robert R Freimuth (4)
Klaus-Peter Adlassnig (1) (5)
Michel Dumontier (6)

1. Center for Medical Statistics ; Informatics ; and Intelligent Systems ; Medical University of Vienna ; Spitalgasse 23 ; 1090 ; Vienna ; Austria
2. Institute of Medical Informatics ; Statistics ; and Documentation ; Medical University of Graz ; Auenbruggerplatz 2 ; 8036 ; Graz ; Austria
3. Department of Biomedical Informatics ; University of Pittsburgh ; 5607 Baum Blvd ; Suite 419 ; Pittsburgh ; PA ; 15206-3701 ; USA
4. Department of Health Sciences Research ; Mayo Clinic ; 200 First Street SW ; Rochester ; MN ; 55905 ; USA
5. Medexter Healthcare GmbH ; Borschkegasse 7/5 ; 1090 ; Vienna ; Austria
6. Stanford Center for Biomedical Informatics Research ; Stanford University ; 1265 Welch Road ; Stanford ; CA ; 94305-5479 ; USA

关键词：Pharmacogenomics ; Ontology ; Automated reasoning ; Personalized medicine ; Clinical decision support

刊名：BMC Medical Informatics and Decision Making

出版年：2015

作者：Fei Chen (1)
Xueqian Zhuang (1)
Liangyu Lin (1)
Pengfei Yu (1)
Ying Wang (1)
Yufang Shi (1) (2)
Guohong Hu (1)
Yu Sun (1) (3) (4) (5)

1. Key Laboratory of Stem Cell Biology ; Institute of Health Sciences ; Shanghai Institutes for Biological Sciences ; Chinese Academy of Sciences/Shanghai Jiaotong University School of Medicine ; Shanghai ; 200031 ; China
2. Soochow Institutes for Translational Medicine ; Soochow University ; Suzhou ; 215123 ; China
3. VA Seattle Medical Center ; Seattle ; WA ; 98108 ; USA
4. Department of Medicine ; University of Washington ; Seattle ; WA ; 98195 ; USA
5. Institute of Health Sciences ; Shanghai Institutes for Biological Sciences (SIBS) ; Chinese Academy of Sciences (CAS) and Shanghai Jiaotong University School of Medicine (SJTUSM) ; 320 Yue Yang Road ; Biological Research Building A ; Shanghai ; 200031 ; China

关键词：Acquired resistance ; Clinical oncology ; Combination therapy ; Distant metastasis ; Immunomodulation ; Targeting strategy ; Therapeutic intervention ; Translational medicine ; Tumor microenvironment

刊名：BMC Medicine

出版年：2015

作者：Carol Yimlui Cheung (1) (2) (3)
M. Kamran Ikram (1) (2) (3)
Ronald Klein (4)
Tien Yin Wong (1) (2) (3)

1. Singapore Eye Research Institute ; Singapore National Eye Centre ; Singapore ; 11 Third Hospital Avenue ; Singapore ; 168751 ; Republic of Singapore
2. Ophthalmology and Visual Sciences Academic Clinical Programme ; Duke-NUS Graduate Medical School ; Singapore ; Republic of Singapore
3. Department of Ophthalmology ; Yong Loo Lin School of Medicine ; National University of Singapore ; Singapore ; Republic of Singapore
4. Ocular Epidemiology Research Group ; Department of Ophthalmology and Visual Sciences ; The University of Wisconsin ; Madison ; WI ; USA

关键词：Diabetes ; Diabetic complications ; Retina ; Retinal microvasculature ; Retinal vascular changes ; Retinal vascular function ; Retinal vascular structure ; Retinal vessels ; Review

刊名：Diabetologia

出版年：2015