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在“Elsevier”中，命中：1,565条，耗时：0.0659738 秒

1.Increased myofilament Cap>2+p> sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice

作者：Bodvaë ; l Frayssep>ap>p> ; p>p>bp>p> ; p>p>1p> ; Florian Weinbergerp>cp>p> ; p>p>1p> ; Sonya C. Bardswellp>dp>p> ; p>p>1p> ; Friederike Cuellop>dp> ; Nicolas Vignierp>ap>p> ; p>p>bp> ; Birgit Geertzp>cp> ; Jutta Starbattyp>cp> ; Elisabeth Krä ; merp>cp> ; Catherine Coiraultp>ap>p> ; p>p>bp> ; Thomas Eschenhagenp>cp> ; Jonathan C. Kentishp>dp> ; Metin Avkiranp>dp> ; Lucie Carrierp>ap>p> ; p>p>bp>p> ; p>p>cp>p> ; p>p>l.carrier@uke.dep>

关键词：cMyBP-C ; cardiac myosin-binding protein C ; cTnI ; cardiac troponin I ; CSQ ; calsequestrin ; HCM ; hypertrophic cardiomyopathy ; Het ; heterozygous Mybpc3-targeted knock-in mice ; KI ; homozygous Mybpc3-targeted knock-in mice ; KO ; homozygous Mybpc3-targeted knock-

刊名：Journal of Molecular and Cellular Cardiology

出版年：2012

2.Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein

作者：Antu K. Deyp>ap>p> ; p>p>antu.dey@novartis.comp> ; Brian Burkep>ap> ; Yide Sunp>ap> ; Karin Hartogp>ap> ; Jonathan L. Heeneyp>bp> ; David Montefiorip>cp> ; Indresh K. Srivastavap>ap>p> ; p>p>1p> ; Susan W. Barnettp>ap>p> ; p>p>susan.barnett@novartis.comp>

关键词：HIV ; SF162 ; gp140 ; Adjuvant ; Carbopol ; MF59

刊名：Vaccine

出版年：2012

3.Cyclic AMP-specific phosphodiesterase, PDE8A1, is activated by protein kinase A-mediated phosphorylation

作者：Kim M. Brownp>1p> ; Louisa C.Y. Leep>1p> ; Jane E. Findlay ; Jonathan P. Day ; George S. Bailliep> ; p>p>George.Baillie@glasgow.ac.ukp>p> ; p>p>G.Baillie@bio.gla.ac.ukp>

关键词：PDE8 ; phosphodiesterase 8 ; PKA ; protein kinase A ; cAMP ; cyclic-AMP ; PI3K ; phosphoinositide 3-kinase ; DNAPK ; DNA_dependent protein kinase ; FSK ; forskolin ; EPAC ; exchange protein directly activated by cAMP ; cGMP ; cyclic guanine monophosphate

刊名：FEBS Letters

出版年：2012

4.In聽vivo targeting and positron emission tomography imaging of tumor vasculature with p>66p>Ga-labeled nano-graphene

作者：Hao Hongp>ap>p> ; p>p>1p> ; Yin Zhangp>bp>p> ; p>p>1p> ; Jonathan W. Englep>bp> ; Tapas R. Nayakp>ap> ; Charles P. Theuerp>cp> ; Robert J. Nicklesp>bp> ; Todd E. Barnhartp>bp> ; Weibo Caip>ap>p> ; p>p>bp>p> ; p>p>dp>p> ; p>p>wcai@uwhealth.orgp>

关键词：Graphene ; 66Ga ; CD105 (endoglin) ; Positron emission tomography (PET) ; Molecular imaging ; Tumor angiogenesis

刊名：Biomaterials

出版年：2012

5.Immuno-inhibitory PD-L1 can be induced by a Peptidoglycan/NOD2 mediated pathway in primary monocytic cells and is deficient in Crohn's patients with homozygous NOD2 mutations.

作者：Rachel E. Hewittp>ap>p> ; p>p>1p> ; Laetitia C. Pelep>ap>p> ; p>p>1p> ; Mark Tremellingp>bp> ; Andrew Metzp>bp> ; Miles Parkesp>bp> ; Jonathan J. Powellp>ap>p> ; p>p>jonathan.powell@mrc-hnr.cam.ac.ukp>

关键词：Peptidoglycan ; NOD2 ; TLR2 ; PD-L1 ; CD14 ; Crohn's disease

刊名：Clinical Immunology

出版年：2012

6.Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint

作者：Lindsey ; A. Shepperdp>1p>p> ; p>p>3p> ; John ; C. Meadowsp>1p>p> ; p>p>3p> ; Alicja ; M. Sochajp>2p>p> ; p>p>3p> ; Theresa ; C. Lancasterp>1p> ; Juan Zoup>2p> ; Graham ; J. Buttrickp>1p> ; Juri Rappsilberp>2p> ; Kevin ; G. Hardwickp>2p>p> ; p>p>kevin.hardwick@ed.ac.ukp> ; Jonathan ; B.A. Millarp>1p>p> ; p>p>j.millar@warwick.ac.ukp>

刊名：Current Biology

出版年：2012

7.Substrate analog studies of the 蠅-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1

作者：Jonathan B. Johnstonp>ap> ; Arti A. Singhp>bp> ; Anaelle A. Claryp>cp> ; Chiung-Kuan Chenp>dp> ; Patricia Y. Hayesp>bp> ; Sharon Chowp>bp> ; James J. De Vossp>bp> ; Paul R. Ortiz de Montellanop>ap>p> ; p>p>ortiz@cgl.ucsf.edup>

关键词：CYP ; cytochrome P450 ; BSTFA ; N ; O-bis(trimethylsilyl)trifluoroacetamide ; DIBAL-H ; diisobutylaluminum hydride ; M尾CD ; methyl 尾-cyclodextrin ; MCE ; mammalian cell entry ; MDR-TB ; multi-drug resistant tuberculosis ; Mtb ; Mycobacterium tuberculosis ; P450 ; cytoch

刊名：Bioorganic and Medicinal Chemistry

出版年：2012

8.A thermosensitive liposome prepared with a Cup>2+p> gradient demonstrates improved pharmacokinetics, drug delivery and antitumor efficacy

作者：Tatsuaki Tagamip>1p>p> ; p>p>2p> ; Jonathan P. Mayp>2p> ; Mark J. Ernsting ; Shyh-Dar Lip> ; p>p>sli@oicr.on.cap>

关键词：Thermosensitive liposomes ; Triggered drug release ; Tumor-targeted drug delivery ; Mild hyperthermia ; Brij78 ; Copper gradient for drug loading

刊名：Journal of Controlled Release

出版年：2012

9.Diastereoselective synthesis of highly functionalized 尾p>2,2,3p>-substituted amino acids from 4-substituted-1,3-oxazinan-6-ones

作者：Nghi H. Nguyenp>ap> ; Brad E. Sleebsp>bp>p> ; p>p>cp> ; Jonathan M. Whitep>dp> ; Andrew B. Hughesp>ap>p> ; p>p>andrew.hughes2@optusnet.com.aup>

关键词：Beta-amino acids ; Oxazinanones ; Stereoselective ; Enolate ; N-Methyl amino acids

刊名：Tetrahedron

出版年：2012

10.The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells

作者：Xiangwen Chen-Deutschp>ap> ; Andrzej Kutnerp>bp> ; Jonathan S. Harrisonp>cp> ; George P. Studzinskip>ap>p> ; p>p>studzins@umdnj.edup>

关键词：Caspases ; AML ; CML ; Vitamin D ; HPK1 pathway ; Q-VD-OPh

刊名：Leukemia Research

出版年：2012

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