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在“Elsevier”中，命中：422条，耗时：0.0869564 秒

1.Combination therapy for hepatocellular carcinoma: Additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib

作者：Anja Lachenmayerp>1p>p> ; p>p>2p> ; Sara Toffaninp>1p>p> ; p>p>3p> ; Laia Cabellosp>1p> ; Clara Alsinetp>1p>p> ; p>p>4p> ; Yujin Hoshidap>5p> ; Augusto Villanuevap>4p> ; Beatriz Minguezp>1p> ; Hung-Wen Tsaip>1p> ; Stephen C. Wardp>1p> ; Swan Thungp>1p> ; Scott L. Friedmanp>1p> ; Josep M. Llovetp>1p>p> ; p>p>4p>p> ; p>p>6p>p> ; p>p>Josep.Llovet@mssm.edup>p> ; p>p>jmllovet@clinic.ub.esp>

关键词：BCLC ; Barcelona Clinic Liver Cancer ; CI ; confidence interval ; FACS ; fluorescent-activated cell sorting ; HCC ; hepatocellular carcinoma ; HBV ; hepatitis B virus ; HCV ; hepatitis C virus ; HDAC ; histone deacetylase ; HDACi ; histone deacetylase inhibitor ; HSP90

刊名：Journal of Hepatology

出版年：2012

2.Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease

作者：Haiqun Jiap>ap> ; Judit Pallosp>bp> ; Vincent Jacquesp>cp> ; Alice Laup>dp> ; Bin Tangp>ap> ; Andrew Cooperp>cp> ; Adeela Syedp>bp> ; Judith Purcellp>bp> ; Yi Chenp>cp> ; Shefali Sharmap>cp> ; Gavin R. Sangreyp>ep> ; Shayna B. Darnellp>ep> ; Heather Plastererp>cp> ; Ghazaleh Sadri-Vakilip>ep> ; Joel M. Gottesfeldp>ap> ; Leslie M. Thompsonp>dp>p> ; p>p>fp> ; James R. Ruschep>cp> ; J. Lawrence Marshp>bp> ; Elizabeth A. Thomasp>ap>p> ; p>p>bthomas@scripps.edup>

关键词：(HDAC) ; histone deacetylase ; (HDACi) ; HDAC inhibitor ; (HD) ; Huntington's disease ; (Ppp1r1b) ; Protein phosphatase 1 ; regulatory (inhibitor) subunit 1B ; (Htt) ; Huntingtin

刊名：Neurobiology of Disease

出版年：2012

3.Baicalin is anti-inflammatory in cigarette smoke-induced inflammatory models in vivo and in vitro: A possible role for HDAC2 activity

作者：Lulu Lip>ap> ; Hong Baop>bp> ; Jinfeng Wup>ap> ; Xiaohong Duanp>ap> ; Baojun Liup>ap> ; Jing Sunp>ap> ; Weiyi Gongp>ap> ; Yubao Lvp>ap> ; Hongying Zhangp>ap> ; Qingli Luop>ap> ; Xiao Wup>ap> ; Jingcheng Dongp>ap>p> ; p>p>jcdong2004@hotmail.comp>

关键词：Baicalin ; Cigarette smoke ; Inflammation ; COPD ; HDAC2

刊名：International Immunopharmacology

出版年：2012

4.Pardoprunox as adjunct therapy to levodopa in patients with Parkinson鈥檚 disease experiencing motor fluctuations: Results of a double-blind, randomized, placebo-controlled, trial

作者：O. Rascolp>ap>p> ; p>p>1p>p> ; p>p>rascol@cict.frp> ; J. Bronzovap>bp>p> ; p>p>1p> ; R.A. Hauserp>cp>p> ; p>p>1p> ; A.E. Langp>dp>p> ; p>p>1p> ; C. Sampaiop>ep>p> ; p>p>1p> ; A. Theeuwesp>fp>p> ; p>p>1p> ; S.V. van de Wittep>bp>p> ; p>p>1p>

关键词：Parkinson&rsquo ; s disease ; Pardoprunox (SLV308) ; Partial dopamine agonist ; Motor fluctuations ; Dyskinesia

刊名：Parkinsonism and Related Disorders

出版年：2012

5.MuLV IN mutants responsive to HDAC inhibitors enhance transcription from unintegrated retroviral DNA

作者：William M. Schneiderp>1p>p> ; p>p>wschneider@rockefeller.edup> ; Dai-tze Wu p>wuta@umdnj.edup> ; Vaibhav Amin p>aminva@umdnj.edup> ; Sriram Aiyer p>aiyerss@umdnj.edup> ; Monica J. Rothp> ; p>p>roth@umdnj.edup>

关键词：IN ; Integrase ; M-MuLV ; Moloney murine leukemia virus ; PIC ; pre-integration complex ; TSA ; Trichostatin A ; HDAC ; histone deacetylase

刊名：Virology

出版年：2012

6.Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms

作者：Christen Lykkegaard Andersenp>ap>p> ; p>p>bp>p> ; p>p>christenla@gmail.comp> ; Hans Hasselbalchp>bp> ; Kirsten Grø ; nbæ ; kp>ap>

关键词：Chronic Ph-negative myeloproliferative disorders ; Tyrosine kinases ; Epigenetic regulation ; Histone acetyltransferase (HAT) genes ; CREEBP ; EP300 ; Histone deacetylases (HDAC) ; Histone deacetylase inhibition (HDACi)

刊名：Leukemia Research

出版年：2012

7.HDAC inhibitor M344 suppresses MCF-7 breast cancer cell proliferation

作者：Angie Yeung ; Rishi K. Bhargava ; Raphael Ahn ; Sarra Bahna ; Na Hyea Kang ; Ayush Lacoul ; Lennard P. Nilesp> ; p>p>niles@mcmaster.cap>

关键词：MTT assay ; p21 ; Apoptosis

刊名：Biomedicine and Pharmacotherapy

出版年：2012

8.NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape

作者：Tsutomu Morip>ap>p> ; p>p>1p>p> ; p>p>tmori@fmu.ac.jpp> ; Daisuke D. Ikedap>bp>p> ; p>p>1p> ; Yoshiki Yamaguchip>cp>p> ; p>p>1p> ; Motoko Unokip>dp>p> ; p>p>1p> ; NIRF Projectp>1p>

关键词：CAN gene ; candidate cancer gene ; CD ; cluster of differentiation ; CDK ; cyclin-dependent kinase ; COPA ; cancer outlier profile analysis ; DNMT ; DNA methyltransferase ; GRN ; gene regulatory network ; HDAC ; histone deacetylase ; H3K9 ; Histone H3 lysine 9 ; ICBP90

刊名：FEBS Letters

出版年：2012

9.HDAg-L variants in covert hepatitis D and HBV occult infection among Amerindians of Argentina: new insights

作者：Cecilia M. Delfinop>ap>p> ; p>p>bp>p> ; p>p>cdelfino@fmed.uba.arp> ; Marí ; a E. Eirinp>ap> ; Carolina Berinip>ap> ; Richard Malanp>cp> ; Emiliano Gentilep>bp> ; Amalia Castillop>bp> ; Williams Pedrozop>cp> ; Ramó ; n Kruppp>cp> ; Jorgelina Blejerp>dp> ; José ; R. Oubiñ ; ap>bp> ; Veró ; nica L. Mathetp>bp>p> ; p>p>1p> ; Mirna M. Biglionep>ap>p> ; p>p>1p>

关键词：Covert hepatitis D infection ; Occult hepatitis B infection ; Amerindians

刊名：Journal of Clinical Virology

出版年：2012

10.Combining microRNA-449a/b with a HDAC inhibitor has a synergistic effect on growth arrest in lung cancer

作者：Hyo Sung Jeonp>ap> ; Soo Young Leep>bp> ; Eun Jin Leep>ap> ; Seong Cheol Yunp>cp> ; Eun Jung Chap>dp> ; Eugene Choip>cp> ; Moon Jun Nap>cp> ; Jae Yong Parkp>ep> ; Jaeku Kangp>fp>p> ; p>p>jaeku@konyang.ac.krp> ; Ji Woong Sonp>bp>p> ; p>p>cp>p> ; p>p>sk1609@hanmail.netp>

关键词：HDAC1 ; MicroRNA ; Non-small cell lung cancer

刊名：Lung Cancer

出版年：2012

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