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在“Elsevier”中，命中：550条，耗时：0.0229929 秒

1.Comparison and evaluation of pharmacokinetics of PFOA and PFOS in the adult rat using a physiologically based pharmacokinetic model

作者：Anne E. Loccisano^a ; ^{ALoccisano@thehamner.org} ; Jerry L. Campbell Jr^a ; John L. Butenhoff^b ; Melvin E. Andersen^a ; Harvey J. Clewell III^a

关键词：PFAAs ; collectively refers to perfluoroalkyl acid carboxylates and sulfonates ; PBPK ; model ; physiologically based pharmacokinetic model ; PFOA ; perfluorooctanoate ; PFOS ; perfluorooctane sulfonate

刊名：Reproductive Toxicology

出版年：2012

2.Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study of the Oral 纬-Secretase Inhibitor BMS-708163 (Avagacestat): Tolerability Profile, Pharmacokinetic Parameters, and Pharmacodynamic Markers

作者：Gary Tong ; MD ; PhD¹ ; ^{Gary.Tong@bms.com} ; Jun-Sheng Wang ; PhD¹ ; Oleksandr Sverdlov ; PhD² ; Shu-Pang Huang ; PhD² ; Randy Slemmon ; PhD¹ ; Robert Croop ; MD² ; Lorna Castaneda ; MS¹ ; Huidong Gu ; MS² ; Oi Wong ; BS² ; Hewei Li ; MD ; PhD² ; Robert M. Berman ; MD³ ; Christina Smith ; DPhil² ; Charles F. Albright ; PhD³ ; Randy C. Dockens ; PhD¹

关键词：avagacestat ; Alzheimer's disease ; A尾1&ndash ; 40 ; gamma-secretase inhibitor ; pharmacodynamic ; pharmacokinetic ; tolerability

刊名：Clinical Therapeutics

出版年：2012

3.Pharmacokinetic comparisons of single herb extract of Fufang Danshen preparation with different combinations of its constituent herbs in rats

作者：Shenshen Yang ; Keru Zhang ; Xia Lin ; Yuqiang Miao ; Lingkuo Meng ; Wei Chen ; Xing Tang ; ^{tangpharm@yahoo.com.cn}

关键词：Fufang Danshen preparation ; Pharmacokinetic ; UPLC&ndash ; ESI-MS/MS ; Interactions ; Compatibility

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2012

4.Pharmacokinetics of a new ivermectin/praziquantel oil suspension after intramuscular administration in pigs

作者：Shusheng Tang^a ; Linlin chen^a ; Zhaoxu Guo^a ; Xiuzhi Hu^a ; ^b ; Jiakang He^c ; Gang Wang^a ; Tingting Zhao^a ; Xilong Xiao^a ; ^{xiaoxl@cau.edu.cn}

关键词：Pharmacokinetics ; Ivermectin ; Praziquantel ; Suspension ; Pigs

刊名：Veterinary Parasitology

出版年：2012

5.Estimation of the duration after methamphetamine injection using a pharmacokinetic model in suspects who caused fatal traffic accidents

作者：Kazuo Matsubara^a ; Masaru Asari^b ; Manabu Suno^c ; Toshio Awaya^a ; Mitsuru Sugawara^d ; Tomohiro Omura^a ; ^b ; Joe Yamamoto^a ; Chikatoshi Maseda^b ; Yoshikazu Tasaki^a ; Hiroshi Shiono^b ; Keiko Shimizu^b ; ^{okeichan@asahikawa-med.ac.jp}

关键词：Methamphetamine ; Pharmacokinetic model ; Traffic accident ; Vehicular homicide

刊名：Legal Medicine

出版年：2012

6.Pharmacokinetic behavior of marbofloxacin after intravenous, subcutaneous and intramuscular administrations in llamas (Lama glama)

作者：Sonia Rubio-Langre^a ; José ; J. De Lucas^a ; Nicolá ; s J. Litterio^b ; Soledad Aguilar^b ; Juan C. Boggio^b ; Manuel I. San André ; s^a ; ^{misanand@vet.ucm.es}

关键词：Pharmacokinetic ; Marbofloxacin ; Llamas ; PK/PD integration

刊名：Small Ruminant Research

出版年：2012

7.Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model

作者：Paulo Paixã ; o^a ; ^b ; ^{ppaixao@ff.ul.pt} ; Luí ; s F. Gouveia^a ; José ; A.G. Morais^a

关键词：Physiological-based pharmacokinetic model of absorption ; In vitro&ndash ; in vivo correlation ; In silico&ndash ; in vivo correlation ; Human absolute bioavailability

刊名：International Journal of Pharmaceutics

出版年：2012

8.Liquid chromatography-electrospray quadrupole linear ion trap mass spectrometry method for the quantitation of palonosetron in human plasma and urine: Application to a pharmacokinetic study

作者：Pengfei Li ; Ping Ma ; Yan Wang ; Weihang Tong ; Jing Wang ; Cheng Wu ; Lihong Liu ; ^{hongllh@yahoo.com.cn}

关键词：Palonosetron ; LC&ndash ; MS/MS ; Pharmacokinetics

刊名：Journal of Chromatography B ; Analytical Technologies in the Biomedical and Life Sciences

出版年：2012

9.Comparative pharmacokinetics of perfluorohexanesulfonate (PFHxS) in rats, mice, and monkeys

作者：Maria Sundströ ; m^a ; ^{maria.sundstrom@mmk.su.se} ; Shu-Ching Chang^b ; ^{s.chang@mmm.com} ; Patricia E. Noker^c ; ^{noker@southernresearch.org} ; Gregory S. Gorman^c ; ^d ; ¹ ; ^{ggorman@samford.edu} ; Jill A. Hart^b ; ^{jahart@mmm.com} ; David J. Ehresman^b ; ^{djehresman@mmm.com} ; Å ; ke Bergman^a ; ^{ake.bergman@mmk.su.se} ; John L. Butenhoff^b ; ^{jlbutenhoff@mmm.com}

关键词：Perfluorohexanesulfonate ; PFHxS ; Pharmacokinetics ; Rats ; Monkeys ; Mice

刊名：Reproductive Toxicology

出版年：2012

10.Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys

作者：Shu-Ching Chang^a ; ^{s.chang@mmm.com} ; Patricia E. Noker^b ; ^{noker@southernresearch.org} ; Gregory S. Gorman^b ; ^c ; ¹ ; ^{ggorman@samford.edu} ; Sheila J. Gibson^a ; ^{sjgibson@mmm.com} ; Jill A. Hart^a ; ^{jahart@mmm.com} ; David J. Ehresman^a ; ^{djehresman@mmm.com} ; John L. Butenhoff^a ; ^{jlbutenhoff@mmm.com}

关键词：Perfluorooctanesulfonate ; PFOS ; Perfluoroalkyls ; Pharmacokinetics ; Rats ; Mice ; Monkeys

刊名：Reproductive Toxicology

出版年：2012

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