搜索页_Bruton s tyrosine kinase

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在“ACS电子期刊”中，命中：19条，耗时：小于0.01 秒

在所有数据库中总计命中：321条

1.Discovery of Novel Bruton’s Tyrosine Kinase (BTK) Inhibitors Bearing a N,9-Diphenyl-9H-purin-2-amine Scaffold

作者：Yang Ge ; Yue Jin ; Changyuan Wang ; Jianbin Zhang ; Zeyao Tang ; Jinyong Peng ; Kexin Liu ; Yanxia Li ; Youwen Zhou ; Xiaodong Ma

刊名：ACS Medicinal Chemistry Letters

出版年：2016

2.Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis

作者：Jian Liu ; Deodial Guiadeen ; Arto Krikorian ; Xiaolei Gao ; James Wang ; Sobhana Babu Boga ; Abdul-Basit Alhassan ; Younong Yu ; Henry Vaccaro ; Shilan Liu ; Chundao Yang ; Hao Wu ; Alan Cooper ; Jos de Man ; Allard Kaptein ; Kevin Maloney ; Viktor Hornak ; Ying-Duo Gao ; Thierry O. Fischmann ; Hans Raaijmakers ; Diep Vu-Pham ; Jeremy Presland ; My Mansueto ; Zangwei Xu ; Erica Leccese ; Jie Zhang-Hoover ; Ian Knemeyer ; Charles G. Garlisi ; Nathan Bays ; Peter Stivers ; Philip E. Brandish ; Alexandra Hicks ; Ronald Kim ; Joseph A. Kozlowski

刊名：ACS Medicinal Chemistry Letters

出版年：2016

3.Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked

作者：Scott H. Watterson ; George V. De Lucca ; Qing Shi ; Charles M. Langevine ; Qingjie Liu ; Douglas G. Batt ; Myra Beaudoin Bertrand ; Hua Gong ; Jun Dai ; Shiuhang Yip ; Peng Li ; Dawn Sun ; Dauh-Rurng Wu ; Chunlei Wang ; Yingru Zhang ; Sarah C. Traeger ; Mark A. Pattoli ; Stacey Skala ; Lihong Cheng ; Mary T. Obermeier ; Rodney Vickery ; Lorell N. Discenza ; Celia J. D’Arienzo ; Yifan Zhang ; Elizabeth Heimrich ; Kathleen M. Gillooly ; Tracy L. Taylor ; Claudine Pulicicchio ; Kim W. McIntyre ; Michael A. Galella ; Andy J. Tebben ; Jodi K. Muckelbauer ; ChiehYing Chang ; Richard Rampulla ; Arvind Mathur ; Luisa Salter-Cid ; Joel C. Barrish ; Percy H. Carter ; Aberra Fura ; James R. Burke ; Joseph A. Tino

刊名：Journal of Medicinal Chemistry

出版年：2016

4.Small Molecule Reversible Inhibitors of Bruton’s Tyrosine Kinase (BTK): Structure–Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177)

作者：George V. De Lucca ; Qing Shi ; Qingjie Liu ; Douglas G. Batt ; Myra Beaudoin Bertrand ; Rick Rampulla ; Arvind Mathur ; Lorell Discenza ; Celia D’Arienzo ; Jun Dai ; Mary Obermeier ; Rodney Vickery ; Yingru Zhang ; Zheng Yang ; Punit Marathe ; Andrew J. Tebben ; Jodi K. Muckelbauer ; ChiehYing J. Chang ; Huiping Zhang ; Kathleen Gillooly ; Tracy Taylor ; Mark A. Pattoli ; Stacey Skala ; Daniel W. Kukral ; Kim W. McIntyre ; Luisa Salter-Cid ; Aberra Fura ; James R. Burke ; Joel C. Barrish ; Percy H. Carter ; Joseph A. Tino

刊名：Journal of Medicinal Chemistry

出版年：2016

5.Synthesis of Diverse 11C-Labeled PET Radiotracers via Direct Incorporation of [11C]CO2

作者：Andrew V. Mossine ; Allen F. Brooks ; Isaac M. Jackson ; Carole A. Quesada ; Phillip Sherman ; Erin L. Cole ; David J. Donnelly ; Peter J. H. Scott ; Xia Shao

刊名：Bioconjugate Chemistry

出版年：2016

6.Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors

作者：Balyn W. Zaro ; Landon R. Whitby ; Kenneth M. Lum ; Benjamin F. Cravatt

刊名：Journal of the American Chemical Society

出版年：2016

7.Label-Free Bottom-Up Proteomic Workflow for Simultaneously Assessing the Target Specificity of Covalent Drug Candidates and Their Off-Target Reactivity to Selected Proteins

作者：Yanou Yang ; Yue-Zhong Shu ; W. Griffith Humphreys

刊名：Chemical Research in Toxicology

出版年：2016

8.Fragment-Based Discovery of a Small Molecule Inhibitor of Bruton鈥檚 Tyrosine Kinase

作者：Christopher R. Smith ; Douglas R. Dougan ; Mallareddy Komandla ; Toufike Kanouni ; Beverly Knight ; J. David Lawson ; Mark Sabat ; Ewan R. Taylor ; Phong Vu ; Corey Wyrick

刊名：Journal of Medicinal Chemistry

出版年：2015

9.Structure-Based Drug Design of RN486, a Potent and Selective Bruton鈥檚 Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis

作者：Yan Lou ; Xiaochun Han ; Andreas Kuglstatter ; Rama K. Kondru ; Zachary K. Sweeney ; Michael Soth ; Joel McIntosh ; Renee Litman ; Judy Suh ; Buelent Kocer ; Dana Davis ; Jaehyeon Park ; Sandra Frauchiger ; Nolan Dewdney ; Hasim Zecic ; Joshua P. Taygerly ; Keshab Sarma ; Junbae Hong ; Ronald J. Hill ; Tobias Gabriel ; David M. Goldstein ; Timothy D. Owens

刊名：Journal of Medicinal Chemistry

出版年：2015

10.Novel Disubstituted Pyrimidines as Inhibitors of Bruton鈥檚 Tyrosine Kinase

作者：Gerard Rosse

刊名：ACS Medicinal Chemistry Letters

出版年：2015

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