搜索页_ EGFR/HER-2 inhibitors

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在“NATURE电子期刊”中，命中：14条，耗时：0.0140261 秒

在所有数据库中总计命中：2,307条

1.Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors

作者：Yong Jia ; Cai-Hong Yun ; Eunyoung Park ; Dalia Ercan ; Mari Manuia ; Jose Juarez ; Chunxiao Xu ; Kevin Rhee ; Ting Chen ; Haikuo Zhang ; Sangeetha Palakurthi ; Jaebong Jang ; Gerald Lelais ; Michael DiDonato ; Badry Bursulaya ; Pierre-Yves Michellys ; Robert Epple ; Thomas H. Marsilje ; Matthew McNeill ; Wenshuo Lu ; Jennifer Harris ; Steven Bender ; Kwok-Kin Wong ; Pasi A. J&#228 ; nne ; Michael J. Eck

关键词：X-ray crystallography ; Cancer ; Drug discovery ; Non-small-cell lung cancer ; Kinases

刊名：Nature

出版年：2016

2.EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors

作者：Christine M. Fillmore ; Chunxiao Xu ; Pooja T. Desai ; Joanne M. Berry ; Samuel P. Rowbotham ; Yi-Jang Lin ; Haikuo Zhang ; Victor E. Marquez ; Peter S. Hammerman ; Kwok-Kin Wong ; Carla F. Kim

关键词：Prognostic markers

刊名：Nature

出版年：2015

3.YLT192, a Novel, Orally Active Bioavailable Inhibitor of VEGFR2 Signaling with Potent Antiangiogenic Activity and Antitumor Efficacy in Preclinical Models

作者：Yong Xia ; Xuejiao Song ; Deliang Li ; Tinghong Ye ; Youzhi Xu ; Hongjun Lin ; Nana Meng ; Guobo Li ; Senyi Deng ; Shuang Zhang ; Li Liu ; Yongxia Zhu ; Jun Zeng ; Qian Lei ; Youli Pan ; Yuquan Wei ; Yinglan Zhao ; Luoting Yu

关键词：Targeted therapies ; Drug development

刊名：Scientific Reports

出版年：2014

4.Electrochemical monitoring of an important biomarker and target protein: VEGFR2 in cell lysates

作者：Tianxiang Wei ; Wenwen Tu ; Bo Zhao ; Yaqian Lan ; Jianchun Bao ; Zhihui Dai

关键词：Membrane proteins ; Chemical tools

刊名：Scientific Reports

出版年：2014

5.BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer

作者：Niki Karachaliou ; Jordi Codony-Servat ; Cristina Teixid&#243 ; Sara Pilotto ; Ana Drozdowskyj ; Carles Codony-Servat ; Ana Gim&#233 ; nez-Capit&#225n ; Miguel Angel Molina-Vila ; Jordi Bertr&#225 ; n-Alamillo ; Radj Gervais ; Bartomeu Massuti ; Teresa Mor&#225n ; Margarita Majem ; Enriqueta Felip ; Enric Carcereny ; Rosario Garc&#237 ; a-Campelo ; Santiago Viteri ; Mar&#237 ; a Gonz&#225 ; lez-Cao ; Daniela Morales-Espinosa ; Alberto Verlicchi ; Elisabetta Crisetti ; Imane Chaib ; Mariacarmela Santarpia ; Jos&#233 ; Luis Ram&#237 ; rez ; Joaquim Bosch-Barrera ; Andr&#233 ; s Felipe Cardona ; Filippo de Marinis ; Guillermo L&#243 ; pez-Vivanco ; Jos&#233 ; Miguel S&#225 ; nchez ; Alain Vergnenegre ; Jos&#233 ; Javier S&#225 ; nchez Hern&#225 ; ndez ; Isabella Sperduti ; Emilio Bria ; Rafael Rosell

刊名：Scientific Reports

出版年：2015

6.Efficacy analysis of tyrosine kinase inhibitors on rare non-small cell lung cancer patients harboring complex EGFR mutations

作者：Liang Peng ; Zhi-Gang Song ; Shun-Chang Jiao

关键词：Biochemistry ; Medical research

刊名：Scientific Reports

出版年：2014

7.Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4

作者：Bryce K. Allen ; Saurabh Mehta ; Stewart W. J. Ember ; Ernst Schonbrunn ; Nagi Ayad ; Stephan C. Sch&#252 ; rer

刊名：Scientific Reports

出版年：2015

8.Therapy-induced tumour secretomes promote resistance and tumour progression

作者：Anna C. Obenauf ; Yilong Zou ; Andrew L. Ji ; Sakari Vanharanta ; Weiping Shu ; Hubing Shi ; Xiangju Kong ; Marcus C. Bosenberg ; Thomas Wiesner ; Neal Rosen ; Roger S. Lo ; Joan Massagu&#233

关键词：Cancer microenvironment ; Cancer therapeutic resistance ; Metastasis

刊名：Nature

出版年：2015

9.Epidermal Growth Factor Receptor (EGFR) Pathway Genes and Interstitial Lung Disease: An Association Study

作者：Chong Li ; Rongrong Wei ; Yava L. Jones-Hall ; Ragini Vittal ; Min Zhang ; Wanqing Liu

关键词：Risk factors ; Respiratory tract diseases

刊名：Scientific Reports

出版年：2014

10.Discovery of a series of novel phenylpiperazine derivatives as EGFR TK inhibitors

作者：Juan Sun ; Xin-Yi Wang ; Peng-Cheng Lv ; Hai-Liang Zhu

刊名：Scientific Reports

出版年：2015

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