A series of novel 10-substituted 3,6-diphenyl-9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione derivatives
were synthesized by condensation of compounds
with amines, which the compounds
were synthesized by
pan class="TH_term3">5-phenylcyclohexane-1,3-dionepan> and aromatic aldehydes according to Knoevenagel, Michael, and
pan class="TH_term4">cyclization reactionspan> in the presence of a very small amount of
pan class="TH_term1 TH_term3">l-prolinepan> as catalyzed at room temperature. The structures of all the synthesized compounds were characterized by IR, 1H NMR, and MS. In addition, the molecular structures of compound
have been determined by single-crystal X-ray diffraction analysis.