Flares during long-term entecavir therapy in chronic hepatitis B

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• 作者：Heng Chi ; Pauline Arends ; Jurrië ; n G P Reijnders ; Ivana Carey ; Ashley Brown ; Massimo Fasano ; David Mutimer ; Katja Deterding ; Ye H Oo ; J&ouml ; rg Petersen ; Florian van Bommel ; Robert J de Knegt ; Teresa A Santantonio ; Thomas Berg ; Tania M Welzel ; Heiner Wedemeyer ; Maria Buti ; Pierre Pradat ; Fabien Zoulim ; Bettina E Hansen ; Harry L A Janssen and for the VIRGIL Surveillance Study Group (European surveillance network for vigilance against viral resistance)
• 刊名：Journal of Gastroenterology and Hepatology
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：31
• 期：11
• 页码：1882-1887
• 全文大小：287K
• ISSN：1440-1746

文摘

The incidence and consequences of flares during first-line nucleos(t)ide analogue therapy are largely unknown. We aimed to investigate the incidence and outcome of alanine aminotransferase (ALT) flares during long-term entecavir (ETV) in chronic hepatitis B (CHB).