IL-1B rs16944 polymorphism is related to septic shock and death

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• 作者：Marí ; a Á ; ngeles Jim&eacute ; nez-Sousa ; Luz M. Medrano ; Pilar Liu ; Raquel Almansa ; Amanda Ferná ; ndez-Rodrí ; guez ; Esther Gó ; mez-Sá ; nchez ; Lucí ; a Rico ; Marí ; a Heredia-Rodrí ; guez ; Estefaní ; a Gó ; mez-Pesquera ; Eduardo Tamayo and Salvador Resino
• 刊名：European Journal of Clinical Investigation
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：47
• 期：1
• 页码：53-62
• 全文大小：111K
• ISSN：1365-2362

文摘

IL-1β is a primary mediator of systemic inflammatory response syndrome (SIRS) and it may lead to shock septic. Our aim was to analyse whether IL-1B rs16944 polymorphism is associated with the onset of septic shock and death after major surgery.