Serum Level of Trefoil Factor 2 can Predict the Extent of Gastric Spasmolytic Polypeptide-Expressing Metaplasia in the H. pylori-Infected Gastric Cancer Relatives

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• 作者：Hsin-Yu Kuo ; Wei-Lun Chang ; Yi-Chun Yeh ; Yu-Ching Tsai ; Chung-Tai Wu ; Hsiu-Chi Cheng ; Hsiao-Bai Yang ; Cheng-Chang Lu and Bor-Shyang Sheu
• 刊名：Helicobacter
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：22
• 期：1
• 全文大小：1145K
• ISSN：1523-5378

文摘

Gastric cancer has familial clustering in incidence, and the familial relatives of gastric cancer sufferers are prone to have spasmolytic polypeptide-expressing metaplasia (SPEM), and intestinal metaplasia (IM) after H. pylori infection. This study tested whether serum pepsinogen I/II and trefoil factor family (TFF) proteins can predict SPEM or IM in the H. pylori-infected relatives of patients with gastric cancer.