Issue Information - Cover

详细信息    查看全文

• 刊名：Microbiology and Immunology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：60
• 期：9
• 页码：i
• 全文大小：993K
• ISSN：1348-0421

文摘

Confocal immunofluorescence image of retinal microglial cells from a C57BL/6J mouse undergoing non-ocular conditions: immunosuppression (by cyclophosphamide) and peripheral inflammation (sublethal colitis chemically-induced with dextran sulphate sodium salt), both administered systemically. Microglial cells (Iba1 positive cells, in green) present an activated state, with an elongated soma and immunoreactivity against MHCIIRT1B antibody (red fluorescence, coexpression is seen in yellow). Cells are spread through different retinal layers (outer plexiform, inner nuclear, inner plexiform and ganglion cell layers). Non-specific immunoreactivity of the secondary antibody (in red) to blood vessels is also observed. Microbiol Immunol: 60:617–625. Article link here.