Zinc-Catalyzed Synthesis of Conjugated Dienoates through Unusual Cross-Couplings of Zinc Carbenes with Diazo Compounds

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• 作者：Sergio Mata ; Marí ; a J. Gonzá ; lez ; Jes&uacute ; s Gonzá ; lez ; Dr. Luis A. Ló ; pez and Dr. Rubé ; n Vicente
• 刊名：Chemistry - A European Journal
• 出版年：2017
• 出版时间：January 23, 2017
• 年：2017
• 卷：23
• 期：5
• 页码：1013-1017
• 全文大小：1959K
• ISSN：1521-3765

文摘

Zinc-catalyzed selective cross-coupling of two carbene sources, such as vinyl diazo compounds and enynones, enabled the synthesis of conjugated dienoate derivatives. This reaction involved the unprecedented coupling of a zinc furyl carbene with vinyl diazo compounds through the γ-carbon. Alternatively, dienoates were also prepared by a commutative cross-coupling of zinc vinyl carbenes generated from cyclopropenes and simple diazo compounds.