Rh-Catalyzed Chemo- and Enantioselective Hydrogenation of Allylic Hydrazones

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• 作者：Qiupeng Hu ; Yanhua Hu ; Yang Liu ; Dr. Zhenfeng Zhang ; Prof. Yangang Liu and Prof. Wanbin Zhang
• 刊名：Chemistry - A European Journal
• 出版年：2017
• 出版时间：January 23, 2017
• 年：2017
• 卷：23
• 期：5
• 页码：1040-1043
• 全文大小：727K
• ISSN：1521-3765

文摘

A highly efficient P-stereogenic diphosphine–rhodium complex was applied to the chemo- and enantioselective hydrogenation of allylic hydrazones for the synthesis of chiral allylic hydrazines in 89–96 % yields and with 82–99 % ee values. This methodology was successfully applied to the preparation of versatile chiral allylic amine derivatives.