Sub-micrometer 20 p>MeV protons or 45 p>MeV lithium spot irradiation enhances yields of dicentric chromosomes due to clustering of DNA double-strand breaks
文摘
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<p id="par0005">Sub-micrometer beam focusing of ions increases dicentric but not DSB yields.p>
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<p id="par0010">More ions per bunch on a grid with correspondingly increased size yield higher RBE.p>
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<p id="par0015">Experiments allow separation of role of DNA damage on the μm and nm scales.p>
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<p id="par0020">Deviation of modelling from experiments helps improve understanding of CA formation.p>
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