I₂/K₂CO₃-promoted ring-opening/cyclization/rearrangement/aromatization sequence: A powerful strategy for the synthesis of polysubstituted furans

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• 作者：Jia-Ming Liu ; Xing-Yu Liu ; Xu-Shun Qing ; Ting Wang ; Cun-De Wang ; ^{wangcd@yzu.edu.cn}
• 关键词：Donor&ndash ; acceptor cyclopropane ; 1-Cyanocyclopropane-1-carboxylate ; 4-Cyanofuran-3-carboxylate ; Domino reaction ; Cyclization
• 刊名：Chinese Chemical Letters
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：28
• 期：2
• 页码：458-462
• 全文大小：659 K
• 卷排序：28

文摘

An efficient and straightforward synthetic method has been developed for the preparation of 4-cyanofuran-3-carboxylate derivatives via iodine/potassium carbonate-promoted ring-opening/cyclization/rearrangement domino reaction of 1-cyanocyclopropane-1-carboxylates, which are a wide range of structurally interesting and pharmacologically significant compounds.