Impact of repeated asenapine treatment on FosB/ΔFosB expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat

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Impact of repeated asenapine treatment on FosB/ΔFosB expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat

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作者：Zuzana Majercikova^a ; Lubica Horvathova^a ; Jana Osacka^a ; Jan Pecenak^b ; Alexander Kiss ; Dr. ; Ph.D. ; D. Sci.^a ; ^{ueenkiss@savba.sk" class="auth_mail" title="E-mail the corresponding author}
关键词：Asenapine ; Chronic unpredictable variable mild stress (CMS) ; FosB/ΔFosB ; Rat
刊名：Brain Research Bulletin
出版年：2016
出版时间：October 2016
年：2016
卷：127
期：Complete
页码：29-37
全文大小：3097 K

文摘

•: Repeated ASE increased FosB/ΔFosB in striatum and shell of the nucleus accumbens.
•: CMS lowered ASE effect on FosB/ΔFosB in striatum and shell of the nucleus accumbens.
•: CMS itself did not affect FosB/ΔFosB expression in any of structures investigated.
•: Highest FosB/ΔFosB expression was seen in prefrontal cortex and lowest in septum.
•: ASE-induced FosB/ΔFosB may take part in brain persisting region-specific changes.

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