A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cúcuta, Colombia

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• 作者：Juan-Manuel Anaya^a ; ¹ ; ^{juan.anaya@urosario.edu.co} ; Yhojan Rodrí ; guez^a ; ¹ ; Diana M. Monsalve^a ; ¹ ; Daniel Vega^b ; Ernesto Ojeda^c ; Diana Gonzá ; lez-Bravo^a ; Mó ; nica Rodrí ; guez-Jimé ; nez^a ; Carlos A. Pinto-Dí ; az^a ; Pablo Chaparro^d ; Marí ; a L. Gunturiz^d ; Aftab A. Ansari^e ; M. Eric Gershwin^f ; ^{megershwin@ucdavis.edu} ; Nicolá ; s Molano-Gonzá ; lez^a ; Carolina Ramí ; rez-Santana^a ; Yeny Acosta-Ampudia^a
• 关键词：Zika virus ; Mycoplasma pneumoniae ; Guillain-Barré ; syndrome ; Transverse myelitis ; Epidemiology ; Public health ; Colombia
• 刊名：Journal of Autoimmunity
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：77
• 期：Complete
• 页码：123-138
• 全文大小：2725 K
• 卷排序：77

文摘

This patient-centered research confirms an increased transmission of ZIKV in Cúcuta. There was a significant increase of severe GBS and other neurological syndromes during the ZIKV outbreak. Low socioeconomic status and a high load of previous infection are associated with GBS development in people infected with ZIKV. More aggressive and efficient control systems for vector-borne viral diseases affecting humans need to be created.