A highly selective fluorescent chemosensor for NADH based on calix[4]arene dimer

详细信息    查看全文

• 作者：Reza Zadmard ; ^{zadmard@ccerci.ac.ir} ; Peyman Akbari-Moghaddam ; Shukufe Darvishi ; Maryam Mirza-Aghayan
• 关键词：Chemosensor ; NADH ; Calix[4]arene ; Fluorescence
• 刊名：Tetrahedron
• 出版年：2017
• 出版时间：2 February 2017
• 年：2017
• 卷：73
• 期：5
• 页码：604-607
• 全文大小：790 K
• 卷排序：73

文摘

A new calix[4]arene dimer (C4D) has been designed and synthesized as a fluorescent chemosensor for the recognition of NADH in aqueous media. This chemosensor showed unique selectivity toward NADH over various biomolecules, with a detection limit of 24.5 nM (16.3 μg L−1). Moreover, the stoichiometry of the C4D-NADH complex formed was found to be 1:1 and the binding constant was calculated to be 3.74 × 105 M−1.