Cholinergic agonist reverses H1-induced memory deficit in mice

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Cholinergic agonist reverses H1-induced memory deficit in mice

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作者：C.E.M. Fernandes ^{ceduardomonici@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; K.R. Serafim ^{kelly.serafim@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; A.C.L. Gianlorenç ; o ^{acgianlorenco@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author} ; R. Mattioli ; ^{mattioli@ufscar.br" class="auth_mail" title="E-mail the corresponding author}
关键词：HA ; histamine ; HNS ; histaminergic neural system ; ACh ; acetylcholine ; EPM ; elevated plus maze ; CPA ; chlorpheniramine maleate ; SAL ; saline ; T1 ; Trial 1 ; T2 ; Trial 2 ; %OAE ; percentage of open arm entries ; %OAT ; percentage of open arm time ; OAE ; open arm entries ; EAE ; enclosed arm entries ; OAT ; open arm time ; EAT ; enclosed arm time ; TE ; total arm entries ; CT ; central area time ; NBM ; nucleus basalis magnocellularis ; BLA ; basolateral complex of the amygdala ; IA ; inhibitory avoidance
刊名：Progress in Neuropsychopharmacology & Biological Psychiatry
出版年：2017
出版时间：4 January 2017
年：2017
卷：72
期：Complete
页码：16-22
全文大小：972 K

文摘

•: Chlorpheniramine and PNU-282987 did not induce effects on anxiety in elevated plus maze.
•: The PNU-282987 per se did not produce effects on emotional memory.
•: Microinjections of PNU-282987 reverse memory deficits induced by chlorpheniramine.

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