Nanosized mesoporous metal-organic framework MIL-101 as a nanocarrier for photoactive hexamolybdenum cluster compounds

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• 作者：Anastasia M. Cheplakova^a ; ^b ; ¹ ; Anastasiya O. Solovieva^c ; ¹ ; Tatiana N. Pozmogova^b ; ^c ; Yuri A. Vorotnikov^a ; Konstantin A. Brylev^a ; ^b ; ^c ; Natalya A. Vorotnikova^a ; Elena V. Vorontsova^d ; Yuri V. Mironov^a ; ^b ; Alexander F. Poveshchenko^c ; Konstantin A. Kovalenko^a ; ^b ; ^{k.a.kovalenko@niic.nsc.ru} ; Michael A. Shestopalov^a ; ^b ; ^c ; ^{shtopy@niic.nsc.ru}
• 关键词：Molybdenum clusters ; MIL-101 ; Luminescence ; Singlet oxygen ; Hep-2 cells ; Phototoxicity
• 刊名：Journal of Inorganic Biochemistry
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：166
• 期：Complete
• 页码：100-107
• 全文大小：933 K
• 卷排序：166

文摘

Molybdenum clusters in mesoporous chromium terephthalate metal-organic framework. Luminescence of hybrids were investigated and compared to clusters in solutions. Cytotoxicity of all compounds were established at low level. Penetration of clusters into Hep-2 cells were observed for pyrazine-free compound. Generation of reactive oxygen species were tested in vitro and in living cells.