Intrinsic functional connectivity of insular cortex and symptoms of sickness during acute experimental inflammation

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Intrinsic functional connectivity of insular cortex and symptoms of sickness during acute experimental inflammation

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作者：Mats Lekander^a ; ^b ; ^c ; ^{Mats.Lekander@ki.se" class="auth_mail" title="E-mail the corresponding author} ; Bianka Karshikoff^a ; ^b ; ^c ; Emilia Johansson^c ; Anne Soop^d ; Peter Fransson^b ; Johan N. Lundströ ; m^c ; ^e ; ^f ; Anna Andreasson^a ; ^b ; ^g ; Martin Ingvar^b ; Predrag Petrovic^b ; John Axelsson^a ; ^b ; ^c ; ¹ ; Gustav Nilsonne^a ; ^b ; ¹
关键词：Endotoxin ; Lipopolysaccharide ; Resting state ; Intrinsic connectivity ; fMRI ; Spontaneous pain ; Sickness behavior ; Inflammation ; Interoception ; Insular cortex
刊名：Brain, Behavior, and Immunity
出版年：2016
出版时间：August 2016
年：2016
卷：56
期：Complete
页码：34-41
全文大小：894 K

文摘

•: LPS injection augmented intrinsic left anterior insula-midcingulate connectivity.
•: This connectivity correlated significantly with increased back pain.
•: The connectivity from other insular seeds were not affected.

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