Caulobacter spp: A Rare Pathogen Responsible for Paucisintomatic Persisitant Meningitis in a Glioblastoma Patient

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• 作者：Federica Penner¹ ; ^{federica.penner@gmail.com} ; Silvia Brossa² ; Anna Maria Barbui² ; Alessandro Ducati¹ ; Rossana Cavallo² ; Francesco Zenga¹
• 关键词：Caulobacter ; Complications ; Glioblastoma ; Meningitis ; Neurosurgery ; Postoperative meningitis
• 刊名：World Neurosurgery
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：96
• 期：Complete
• 页码：611.e11-611.e13
• 全文大小：812 K
• 卷排序：96

文摘

Caulobacter spp. are Gram-negative bacteria that have rarely been found to be pathogenic in humans.Case DescriptionThis report describes the first case, to our knowledge, of meningitis in an adult patient caused by Caulobacter spp. A 75-year-old man was operated for a glioblastoma with no evident signs of primary infection in the wound site. Eight days after surgery, the patient developed signs and symptoms of meningitis. Caulobacter was then isolated on 3 separate occasions in the patient's cerebrospinal fluid. Thereafter, specific antibiotic therapy began. After 2 weeks of therapy, the patient was discharged with complete resolution of any related symptoms.ConclusionsCaulobacter spp. can cause adult meningitis even where there is no evidence of surgical site infection.