Longitudinal reproducibility of default-mode network connectivity in healthy elderly participants: A multicentric resting-state fMRI study

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Longitudinal reproducibility of default-mode network connectivity in healthy elderly participants: A multicentric resting-state fMRI study

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作者：Jorge Jovicich^a ; ¹ ; ^{jorge.jovicich@unitn.it" class="auth_mail" title="E-mail the corresponding author} ; Ludovico Minati^a ; ^af ; ¹ ; Moira Marizzoni^b ; Rocco Marchitelli^a ; Roser Sala-Llonch^c ; David Bartré ; s-Faz^c ; Jennifer Arnold^d ; Jens Benninghoff^d ; Ute Fiedler^d ; Luca Roccatagliata^e ; ^f ; Agnese Picco^g ; Flavio Nobili^g ; Oliver Blin^h ; Stephanie Bomboisⁱ ; Renaud Lopesⁱ ; Ré ; gis Bordetⁱ ; Julien Sein^j ; Jean-Philippe Ranjeva^j ; Mira Didic^k ; ^l ; Hé ; lè ; ne Gros-Dagnac^m ; ⁿ ; Pierre Payoux^m ; ⁿ ; Giada Zoccatelli^o ; Franco Alessandrini^o ; Alberto Beltramello^o ; Nú ; ria Bargalló ; ^p ; Antonio Ferretti^q ; ^r ; Massimo Caulo^q ; ^r ; Marco Aiello^s ; Carlo Cavaliere^s ; Andrea Soricelli^s ; ^t ; Lucilla Parnetti^u ; Roberto Tarducci^v ; Piero Floridi^ae ; Magda Tsolaki^w ; Manos Constantinidis^x ; Antonios Drevelegas^x ; ^y ; Paolo Maria Rossini^z ; ^aa ; Camillo Marra^ab ; Peter Schö ; nknecht^aj ; Tilman Hensch^aj ; Karl-Titus Hoffmann^ac ; Joost P. Kuijer^ai ; Pieter Jelle Visser^ah ; ^ag ; Frederik Barkhof^ah ; Giovanni B. Frisoni^b ; ^ad ; The PharmaCog Consortium
关键词：Default Mode Network ; Reproducibility ; Functional connectivity ; Multi-center ; Multi-site MRI
刊名：NeuroImage
出版年：2016
出版时间：1 January 2016
年：2016
卷：124
期：part_PA
页码：442-454
全文大小：2503 K

文摘

•: We implement a multi-site 3 T MRI protocol for resting state fMRI in 13 sites.
•: We acquire across-session test–retest (TRT) data on 64 healthy elderly participants.
•: Despite harmonization strong phantom and brain tSNR differences remain across sites.
•: TRT error of regional DMN functional connectivity is consistent across sites.
•: ICA yields more reliable DMN connectivity measurements relative to SBA.

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